id author title date pages extension mime words sentences flesch summary cache txt cord-334583-825kmicf Bonyah, Ebenezer Optimal control application to an Ebola model 2016-03-08 .txt text/plain 3579 214 57 Optimal control theory is applied to a system of ordinary differential equations which is modeling Ebola infection through three different routes including contact between humans and a dead body. The holding is incorporated in the model by adding a control term that may minimize the treatment failure rate of individuals with Ebola disease. The "case holding" control, u 2 (t) deals with effort needed to identify the proportion of typical Ebola exposed individuals that is known and will be put under treatment in order to reduce the number of individuals that may turn to be infectious. The term u 3 (t) deals with the effort that ensures those that are infectious both in the first and super infection stages are given treatment and monitored to take their drugs in order to minimize the number of individuals developing and dying of Ebola. In this work, mathematical model of Ebola disease with three possible routes of transmission that include prevention and two treatment measures as optimal control has been examined. ./cache/cord-334583-825kmicf.txt ./txt/cord-334583-825kmicf.txt