id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-004982-q9wsiimn	Rohmann, Kristina	Innate immunity in the human lung: pathogen recognition and lung disease	2010-10-09		.txt	text/plain	4190	222	39	PRRs are expressed by alveolar macrophages, lung epithelial cells and dendritic cells responsible for the first reactions to invading pathogens (Bals and Hiemstra 2004; Opitz et al. In the lung, several host cells including macrophages, dendritic cells (DCs), lung epithelial and endothelial cells express TLRs. Different combinations of TLRs can be found on different respiratory cells (see also Table 2 ) and the simultaneous activation of several TLRs might lead to a more pathogenspecific immune response (Bals and Hiemstra 2004; Krishnan et al. Activation of the TLR4 receptor complex by the recognition of LPS is followed by intracellular signal transduction including the adaptor molecule MyD88 and leading to the production and secretion of proinflammatory cytokines (Wieland et al. The pattern recognition receptor Nod1 activates CCAAT/enhancer binding protein beta signalling in lung epithelial cells Toll-like receptor 4 mediates innate immune responses to Haemophilus influenzae infection in mouse lung	./cache/cord-004982-q9wsiimn.txt	./txt/cord-004982-q9wsiimn.txt