id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-048201-8qnrcgnk	Slebos, Dirk-Jan	Heme oxygenase-1 and carbon monoxide in pulmonary medicine	2003-08-07		.txt	text/plain	7600	399	37	Many studies have suggested that HO-1 acts as an inducible defense against oxidative stress, in models of inflammation, ischemia-reperfusion, hypoxia, and hyperoxia-mediated injury (reviewed in [3] ). Cell-culture studies have suggested that the protective effects of HO-1 overexpression fall within a critical range, such that the excess production of HO-1 or HO-2 may be counterprotective due to a transient excess of reactive iron generated during active heme metabolism [35, 36] . Transfer of heme oxygenase 1 cDNA by a replication-deficient adenovirus enhances interleukin-10 production from alveolar macrophages that attenuates lipopolysaccharide-induced acute lung injury in mice Heme oxygenase-1: function, regulation, and implication of a novel stress-inducible protein in oxidant-induced lung injury Raised levels of exhaled carbon monoxide are associated with an increased expression of heme oxygenase-1 in airway macrophages in asthma: a new marker of oxidative stress Exogenous administration of heme oxygenase-1 by gene transfer provides protection against hyperoxia-induced lung injury	./cache/cord-048201-8qnrcgnk.txt	./txt/cord-048201-8qnrcgnk.txt