id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-315249-yclnl87n	Read, R. C.	Infection in acute exacerbations of chronic bronchitis: a clinical perspective	1999-12-31		.txt	text/plain	2660	131	41	(1999) 93, [845] [846] [847] [848] [849] [850] Topical Reviews Infection in acute exacerbations of chronic bronchitis: a clinical perspective Introduction Chronic obstructive pulmonary disease (COPD) is characterized by irreversible airflow obstruction due to chronic bronchitis or emphysema; this is defined as a ratio of forced expiratory volume in 1 set: forced vital capacity (FEVI: FVC) of less than 70%. Therefore at the very least, even if infection with bacterial pathogens is not the cause of acute exacerbations, they are clearly flourishing in the lower airways in some of these patients, in association with an inflammatory infiltrate (as evidenced by a yield of neutrophils in sputum). influenzae isolated from sputum of patients with COPD has demonstrated that a single strain may persist for many months within the lower respiratory tract mucosa of these patients, and remains present even if there have been acute exacerbations of COPD which have been treated with antibiotics (9).	./cache/cord-315249-yclnl87n.txt	./txt/cord-315249-yclnl87n.txt