id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-319163-d1oj15cw	Lee, Jinju	The Role of Autophagy in Eosinophilic Airway Inflammation	2019-02-04		.txt	text/plain	4082	239	35	Genetic variant in the autophagy gene ATG5 is associated with asthma pathogenesis, and autophagy regulates apoptotic pathways in epithelial cells in individuals with chronic obstructive pulmonary disease. For example, formation of double-membrane autophagosomes in fibroblasts from severe asthmatic patients has been observed by electron microscopy (18, 19) , and genetic variants of the autophagy gene Atg5 are associated with promotion of airway remodeling and loss of lung function in childhood asthma (20) . Eosinophils are a major type of inflammatory cell that play an important role in airway inflammatory diseases, including asthma (21) (22) (23) . Although evidence suggests that autophagy and eosinophils play important roles in immune responses and airway inflammation, few studies have examined the association between autophagy and eosinophils in inflammatory diseases. Eosinophilic airway inflammation: role in asthma and chronic obstructive pulmonary disease	./cache/cord-319163-d1oj15cw.txt	./txt/cord-319163-d1oj15cw.txt