id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-320153-a0bqliei	Ezzeldin, Nada	Association of TNF-α –308G/A, SP-B 1580 C/T, IL-13 –1055 C/T gene polymorphisms and latent adenoviral infection with chronic obstructive pulmonary disease in an Egyptian population	2012-05-09		.txt	text/plain	3941	211	50	title: Association of TNF-α –308G/A, SP-B 1580 C/T, IL-13 –1055 C/T gene polymorphisms and latent adenoviral infection with chronic obstructive pulmonary disease in an Egyptian population In this study, we aimed to investigate the possible association of the TNF-α –308, SPB+1580, IL-13 –1055 gene polymorphisms and latent adenovirus C infection with COPD in an Egyptian population. CONCLUSIONS: The COPD is a disease caused by the interaction of combined genes and environmental influences, in the presence of smoking and latent adenovirus C infection, TNF-α –308A, SPB +1580 T and IL-13 –1055 T polymorphisms predispose to the development of COPD. Meanwhile, the genotype distribution of the IL-13 -1055 C/T polymorphism showed no signifi-cant difference between the studied groups although there was a high frequency of the homozygous T genotype in COPD patients (20%) compared to the resistant smokers (2.8%) and nonsmokers (6.7%) (Table IV, Figure 4 ).	./cache/cord-320153-a0bqliei.txt	./txt/cord-320153-a0bqliei.txt