id author title date pages extension mime words sentences flesch summary cache txt cord-343607-yu5n9eur Wesseling, Geertjan Occasional review: Influenza in COPD: pathogenesis, prevention, and treatment 2007-03-17 .txt text/plain 3633 206 45 Influenza viruses cause respiratory tract infections that in patients with underlying lung diseases such as chronic obstructive pulmonary disease (COPD) are associated with exacerbations and excess morbidity and mortality. Viral infections including infl uenza, respiratory syncytial virus (RSV), and many other viruses are important causes of exacerbations, excess morbidity and mortality in COPD (Wedzicha 2004; Wilkinson et al 2006) . Considering the infl uence of different respiratory viruses in stable COPD and the important role of viral infections in exacerbations, vaccination is a potentially effective way to reduce morbidity and mortality caused by exacerbations. In a randomized clinical trial, Wongsurakiat and colleagues (2004) demonstrated that infl uenza vaccination is highly effective in the prevention of acute respiratory illness related to infl uenza virus infection, regardless of severity of COPD, comorbid diseases, age, gender, or smoking status. ./cache/cord-343607-yu5n9eur.txt ./txt/cord-343607-yu5n9eur.txt