id	sid	tid	token	lemma	pos
cord-017784-4r3fpmlb	1	1	key	key	JJ
cord-017784-4r3fpmlb	1	2	:	:	:
cord-017784-4r3fpmlb	1	3	cord-017784	cord-017784	NN
cord-017784-4r3fpmlb	1	4	-	-	HYPH
cord-017784-4r3fpmlb	1	5	4r3fpmlb	4r3fpmlb	CD
cord-017784-4r3fpmlb	2	1	authors	author	NNS
cord-017784-4r3fpmlb	2	2	:	:	:
cord-017784-4r3fpmlb	2	3	Foccillo	Foccillo	NNP
cord-017784-4r3fpmlb	2	4	,	,	,
cord-017784-4r3fpmlb	2	5	Giampiero	Giampiero	NNP
cord-017784-4r3fpmlb	2	6	title	title	NN
cord-017784-4r3fpmlb	2	7	:	:	:
cord-017784-4r3fpmlb	3	1	The	the	DT
cord-017784-4r3fpmlb	3	2	Infections	infection	NNS
cord-017784-4r3fpmlb	3	3	Causing	cause	VBG
cord-017784-4r3fpmlb	3	4	Acute	acute	JJ
cord-017784-4r3fpmlb	3	5	Respiratory	respiratory	JJ
cord-017784-4r3fpmlb	3	6	Failure	failure	NN
cord-017784-4r3fpmlb	3	7	in	in	IN
cord-017784-4r3fpmlb	3	8	Elderly	Elderly	NNP
cord-017784-4r3fpmlb	3	9	Patients	Patients	NNP
cord-017784-4r3fpmlb	3	10	date	date	NN
cord-017784-4r3fpmlb	3	11	:	:	:
cord-017784-4r3fpmlb	3	12	2019	2019	CD
cord-017784-4r3fpmlb	3	13	-	-	HYPH
cord-017784-4r3fpmlb	3	14	08	08	CD
cord-017784-4r3fpmlb	3	15	-	-	HYPH
cord-017784-4r3fpmlb	3	16	06	06	CD
cord-017784-4r3fpmlb	3	17	journal	journal	NN
cord-017784-4r3fpmlb	3	18	:	:	:
cord-017784-4r3fpmlb	3	19	Ventilatory	Ventilatory	NNP
cord-017784-4r3fpmlb	3	20	Support	Support	NNP
cord-017784-4r3fpmlb	3	21	and	and	CC
cord-017784-4r3fpmlb	3	22	Oxygen	Oxygen	NNP
cord-017784-4r3fpmlb	3	23	Therapy	Therapy	NNP
cord-017784-4r3fpmlb	3	24	in	in	IN
cord-017784-4r3fpmlb	3	25	Elder	Elder	NNP
cord-017784-4r3fpmlb	3	26	,	,	,
cord-017784-4r3fpmlb	3	27	Palliative	Palliative	NNP
cord-017784-4r3fpmlb	3	28	and	and	CC
cord-017784-4r3fpmlb	3	29	End	end	NN
cord-017784-4r3fpmlb	3	30	-	-	HYPH
cord-017784-4r3fpmlb	3	31	of	of	IN
cord-017784-4r3fpmlb	3	32	-	-	HYPH
cord-017784-4r3fpmlb	3	33	Life	life	NN
cord-017784-4r3fpmlb	3	34	Care	Care	NNP
cord-017784-4r3fpmlb	3	35	Patients	patient	NNS
cord-017784-4r3fpmlb	3	36	DOI	DOI	NNP
cord-017784-4r3fpmlb	3	37	:	:	:
cord-017784-4r3fpmlb	3	38	10.1007/978	10.1007/978	CD
cord-017784-4r3fpmlb	3	39	-	-	HYPH
cord-017784-4r3fpmlb	3	40	3	3	CD
cord-017784-4r3fpmlb	3	41	-	-	HYPH
cord-017784-4r3fpmlb	3	42	030	030	CD
cord-017784-4r3fpmlb	3	43	-	-	HYPH
cord-017784-4r3fpmlb	3	44	26664	26664	CD
cord-017784-4r3fpmlb	3	45	-	-	SYM
cord-017784-4r3fpmlb	3	46	6_5	6_5	CD
cord-017784-4r3fpmlb	3	47	sha	sha	NNP
cord-017784-4r3fpmlb	3	48	:	:	:
cord-017784-4r3fpmlb	3	49	95389a6df57c4ff3cb374ef521db1ec86ffbe513	95389a6df57c4ff3cb374ef521db1ec86ffbe513	CD
cord-017784-4r3fpmlb	3	50	doc_id	doc_id	CD
cord-017784-4r3fpmlb	3	51	:	:	:
cord-017784-4r3fpmlb	3	52	17784	17784	CD
cord-017784-4r3fpmlb	3	53	cord_uid	cord_uid	NNS
cord-017784-4r3fpmlb	3	54	:	:	:
cord-017784-4r3fpmlb	3	55	4r3fpmlb	4r3fpmlb	CD
cord-017784-4r3fpmlb	4	1	The	the	DT
cord-017784-4r3fpmlb	4	2	immune	immune	JJ
cord-017784-4r3fpmlb	4	3	system	system	NN
cord-017784-4r3fpmlb	4	4	of	of	IN
cord-017784-4r3fpmlb	4	5	older	old	JJR
cord-017784-4r3fpmlb	4	6	individuals	individual	NNS
cord-017784-4r3fpmlb	4	7	declines	decline	VBZ
cord-017784-4r3fpmlb	4	8	with	with	IN
cord-017784-4r3fpmlb	4	9	advancing	advance	VBG
cord-017784-4r3fpmlb	4	10	age	age	NN
cord-017784-4r3fpmlb	4	11	(	(	-LRB-
cord-017784-4r3fpmlb	4	12	“	"	``
cord-017784-4r3fpmlb	4	13	immunosenescence	immunosenescence	NNP
cord-017784-4r3fpmlb	4	14	”	"	''
cord-017784-4r3fpmlb	4	15	)	)	-RRB-
cord-017784-4r3fpmlb	5	1	increasing	increase	VBG
cord-017784-4r3fpmlb	5	2	susceptibility	susceptibility	NN
cord-017784-4r3fpmlb	5	3	to	to	IN
cord-017784-4r3fpmlb	5	4	infection	infection	NN
cord-017784-4r3fpmlb	5	5	,	,	,
cord-017784-4r3fpmlb	5	6	as	as	RB
cord-017784-4r3fpmlb	5	7	well	well	RB
cord-017784-4r3fpmlb	5	8	as	as	IN
cord-017784-4r3fpmlb	5	9	to	to	IN
cord-017784-4r3fpmlb	5	10	an	an	DT
cord-017784-4r3fpmlb	5	11	increased	increase	VBN
cord-017784-4r3fpmlb	5	12	risk	risk	NN
cord-017784-4r3fpmlb	5	13	of	of	IN
cord-017784-4r3fpmlb	5	14	a	a	DT
cord-017784-4r3fpmlb	5	15	worse	bad	JJR
cord-017784-4r3fpmlb	5	16	outcome	outcome	NN
cord-017784-4r3fpmlb	5	17	.	.	.
cord-017784-4r3fpmlb	6	1	Severe	severe	JJ
cord-017784-4r3fpmlb	6	2	community	community	NN
cord-017784-4r3fpmlb	6	3	-	-	HYPH
cord-017784-4r3fpmlb	6	4	acquired	acquire	VBN
cord-017784-4r3fpmlb	6	5	pneumonia	pneumonia	NN
cord-017784-4r3fpmlb	6	6	and	and	CC
cord-017784-4r3fpmlb	6	7	acute	acute	JJ
cord-017784-4r3fpmlb	6	8	exacerbations	exacerbation	NNS
cord-017784-4r3fpmlb	6	9	of	of	IN
cord-017784-4r3fpmlb	6	10	chronic	chronic	JJ
cord-017784-4r3fpmlb	6	11	obstructive	obstructive	JJ
cord-017784-4r3fpmlb	6	12	pulmonary	pulmonary	JJ
cord-017784-4r3fpmlb	6	13	disease	disease	NN
cord-017784-4r3fpmlb	6	14	(	(	-LRB-
cord-017784-4r3fpmlb	6	15	AECOPD	AECOPD	NNP
cord-017784-4r3fpmlb	6	16	)	)	-RRB-
cord-017784-4r3fpmlb	6	17	are	be	VBP
cord-017784-4r3fpmlb	6	18	causes	cause	NNS
cord-017784-4r3fpmlb	6	19	of	of	IN
cord-017784-4r3fpmlb	6	20	acute	acute	JJ
cord-017784-4r3fpmlb	6	21	respiratory	respiratory	JJ
cord-017784-4r3fpmlb	6	22	failure	failure	NN
cord-017784-4r3fpmlb	6	23	(	(	-LRB-
cord-017784-4r3fpmlb	6	24	ARF	ARF	NNP
cord-017784-4r3fpmlb	6	25	)	)	-RRB-
cord-017784-4r3fpmlb	6	26	in	in	IN
cord-017784-4r3fpmlb	6	27	elderly	elderly	JJ
cord-017784-4r3fpmlb	6	28	patients	patient	NNS
cord-017784-4r3fpmlb	6	29	.	.	.
cord-017784-4r3fpmlb	7	1	Non	non	JJ
cord-017784-4r3fpmlb	7	2	-	-	JJ
cord-017784-4r3fpmlb	7	3	invasive	invasive	JJ
cord-017784-4r3fpmlb	7	4	mechanical	mechanical	JJ
cord-017784-4r3fpmlb	7	5	ventilation	ventilation	NN
cord-017784-4r3fpmlb	7	6	(	(	-LRB-
cord-017784-4r3fpmlb	7	7	NIV	NIV	NNP
cord-017784-4r3fpmlb	7	8	)	)	-RRB-
cord-017784-4r3fpmlb	7	9	is	be	VBZ
cord-017784-4r3fpmlb	7	10	effective	effective	JJ
cord-017784-4r3fpmlb	7	11	in	in	IN
cord-017784-4r3fpmlb	7	12	the	the	DT
cord-017784-4r3fpmlb	7	13	treatment	treatment	NN
cord-017784-4r3fpmlb	7	14	of	of	IN
cord-017784-4r3fpmlb	7	15	patients	patient	NNS
cord-017784-4r3fpmlb	7	16	with	with	IN
cord-017784-4r3fpmlb	7	17	ARF	ARF	NNP
cord-017784-4r3fpmlb	7	18	,	,	,
cord-017784-4r3fpmlb	7	19	above	above	IN
cord-017784-4r3fpmlb	7	20	all	all	DT
cord-017784-4r3fpmlb	7	21	in	in	IN
cord-017784-4r3fpmlb	7	22	case	case	NN
cord-017784-4r3fpmlb	7	23	of	of	IN
cord-017784-4r3fpmlb	7	24	AECOPD	AECOPD	NNP
cord-017784-4r3fpmlb	7	25	.	.	.
cord-017784-4r3fpmlb	8	1	Aging	age	VBG
cord-017784-4r3fpmlb	8	2	is	be	VBZ
cord-017784-4r3fpmlb	8	3	accompanied	accompany	VBN
cord-017784-4r3fpmlb	8	4	by	by	IN
cord-017784-4r3fpmlb	8	5	profound	profound	JJ
cord-017784-4r3fpmlb	8	6	morphological	morphological	JJ
cord-017784-4r3fpmlb	8	7	and	and	CC
cord-017784-4r3fpmlb	8	8	physiological	physiological	JJ
cord-017784-4r3fpmlb	8	9	alterations	alteration	NNS
cord-017784-4r3fpmlb	8	10	.	.	.
cord-017784-4r3fpmlb	9	1	In	in	IN
cord-017784-4r3fpmlb	9	2	particular	particular	JJ
cord-017784-4r3fpmlb	9	3	,	,	,
cord-017784-4r3fpmlb	9	4	the	the	DT
cord-017784-4r3fpmlb	9	5	immune	immune	JJ
cord-017784-4r3fpmlb	9	6	system	system	NN
cord-017784-4r3fpmlb	9	7	undergoes	undergo	VBZ
cord-017784-4r3fpmlb	9	8	a	a	DT
cord-017784-4r3fpmlb	9	9	complex	complex	JJ
cord-017784-4r3fpmlb	9	10	series	series	NN
cord-017784-4r3fpmlb	9	11	of	of	IN
cord-017784-4r3fpmlb	9	12	remodeling	remodeling	NN
cord-017784-4r3fpmlb	9	13	/	/	SYM
cord-017784-4r3fpmlb	9	14	restructuring	restructuring	NN
cord-017784-4r3fpmlb	9	15	events	event	NNS
cord-017784-4r3fpmlb	9	16	,	,	,
cord-017784-4r3fpmlb	9	17	involving	involve	VBG
cord-017784-4r3fpmlb	9	18	almost	almost	RB
cord-017784-4r3fpmlb	9	19	all	all	DT
cord-017784-4r3fpmlb	9	20	compartments	compartment	NNS
cord-017784-4r3fpmlb	9	21	,	,	,
cord-017784-4r3fpmlb	9	22	both	both	DT
cord-017784-4r3fpmlb	9	23	cell	cell	NN
cord-017784-4r3fpmlb	9	24	-	-	HYPH
cord-017784-4r3fpmlb	9	25	mediated	mediate	VBN
cord-017784-4r3fpmlb	9	26	immunity	immunity	NN
cord-017784-4r3fpmlb	9	27	and	and	CC
cord-017784-4r3fpmlb	9	28	humoral	humoral	JJ
cord-017784-4r3fpmlb	9	29	immune	immune	JJ
cord-017784-4r3fpmlb	9	30	responses	response	NNS
cord-017784-4r3fpmlb	9	31	.	.	.
cord-017784-4r3fpmlb	10	1	This	this	DT
cord-017784-4r3fpmlb	10	2	process	process	NN
cord-017784-4r3fpmlb	10	3	termed	term	VBD
cord-017784-4r3fpmlb	10	4	immunosenescence	immunosenescence	JJ
cord-017784-4r3fpmlb	10	5	or	or	CC
cord-017784-4r3fpmlb	10	6	immune	immune	JJ
cord-017784-4r3fpmlb	10	7	dysregulation	dysregulation	NN
cord-017784-4r3fpmlb	10	8	,	,	,
cord-017784-4r3fpmlb	10	9	together	together	RB
cord-017784-4r3fpmlb	10	10	changes	change	NNS
cord-017784-4r3fpmlb	10	11	in	in	IN
cord-017784-4r3fpmlb	10	12	lung	lung	NN
cord-017784-4r3fpmlb	10	13	function	function	NN
cord-017784-4r3fpmlb	10	14	who	who	WP
cord-017784-4r3fpmlb	10	15	occur	occur	VBP
cord-017784-4r3fpmlb	10	16	with	with	IN
cord-017784-4r3fpmlb	10	17	advancing	advance	VBG
cord-017784-4r3fpmlb	10	18	age	age	NN
cord-017784-4r3fpmlb	10	19	,	,	,
cord-017784-4r3fpmlb	10	20	play	play	VB
cord-017784-4r3fpmlb	10	21	a	a	DT
cord-017784-4r3fpmlb	10	22	critical	critical	JJ
cord-017784-4r3fpmlb	10	23	role	role	NN
cord-017784-4r3fpmlb	10	24	in	in	IN
cord-017784-4r3fpmlb	10	25	the	the	DT
cord-017784-4r3fpmlb	10	26	manifestation	manifestation	NN
cord-017784-4r3fpmlb	10	27	of	of	IN
cord-017784-4r3fpmlb	10	28	age	age	NN
cord-017784-4r3fpmlb	10	29	-	-	HYPH
cord-017784-4r3fpmlb	10	30	related	relate	VBN
cord-017784-4r3fpmlb	10	31	pulmonary	pulmonary	JJ
cord-017784-4r3fpmlb	10	32	diseases	disease	NNS
cord-017784-4r3fpmlb	10	33	such	such	JJ
cord-017784-4r3fpmlb	10	34	as	as	IN
cord-017784-4r3fpmlb	10	35	infections	infection	NNS
cord-017784-4r3fpmlb	10	36	(	(	-LRB-
cord-017784-4r3fpmlb	10	37	i.e.	i.e.	FW
cord-017784-4r3fpmlb	10	38	,	,	,
cord-017784-4r3fpmlb	10	39	pneumonia	pneumonia	NN
cord-017784-4r3fpmlb	10	40	)	)	-RRB-
cord-017784-4r3fpmlb	10	41	,	,	,
cord-017784-4r3fpmlb	10	42	chronic	chronic	JJ
cord-017784-4r3fpmlb	10	43	obstructive	obstructive	JJ
cord-017784-4r3fpmlb	10	44	pulmonary	pulmonary	JJ
cord-017784-4r3fpmlb	10	45	disease	disease	NN
cord-017784-4r3fpmlb	10	46	(	(	-LRB-
cord-017784-4r3fpmlb	10	47	COPD	COPD	NNP
cord-017784-4r3fpmlb	10	48	)	)	-RRB-
cord-017784-4r3fpmlb	10	49	,	,	,
cord-017784-4r3fpmlb	10	50	and	and	CC
cord-017784-4r3fpmlb	10	51	increased	increase	VBD
cord-017784-4r3fpmlb	10	52	the	the	DT
cord-017784-4r3fpmlb	10	53	risk	risk	NN
cord-017784-4r3fpmlb	10	54	for	for	IN
cord-017784-4r3fpmlb	10	55	develop	develop	VB
cord-017784-4r3fpmlb	10	56	sepsis	sepsis	NN
cord-017784-4r3fpmlb	10	57	[	[	-LRB-
cord-017784-4r3fpmlb	10	58	1	1	CD
cord-017784-4r3fpmlb	10	59	]	]	-RRB-
cord-017784-4r3fpmlb	10	60	.	.	.
cord-017784-4r3fpmlb	11	1	Respiratory	respiratory	JJ
cord-017784-4r3fpmlb	11	2	failure	failure	NN
cord-017784-4r3fpmlb	11	3	is	be	VBZ
cord-017784-4r3fpmlb	11	4	not	not	RB
cord-017784-4r3fpmlb	11	5	a	a	DT
cord-017784-4r3fpmlb	11	6	disease	disease	NN
cord-017784-4r3fpmlb	11	7	per	per	FW
cord-017784-4r3fpmlb	11	8	se	se	FW
cord-017784-4r3fpmlb	11	9	but	but	CC
cord-017784-4r3fpmlb	11	10	a	a	DT
cord-017784-4r3fpmlb	11	11	consequence	consequence	NN
cord-017784-4r3fpmlb	11	12	of	of	IN
cord-017784-4r3fpmlb	11	13	the	the	DT
cord-017784-4r3fpmlb	11	14	problems	problem	NNS
cord-017784-4r3fpmlb	11	15	that	that	WDT
cord-017784-4r3fpmlb	11	16	interfere	interfere	VBP
cord-017784-4r3fpmlb	11	17	with	with	IN
cord-017784-4r3fpmlb	11	18	the	the	DT
cord-017784-4r3fpmlb	11	19	ability	ability	NN
cord-017784-4r3fpmlb	11	20	to	to	TO
cord-017784-4r3fpmlb	11	21	breathe	breathe	VB
cord-017784-4r3fpmlb	11	22	.	.	.
cord-017784-4r3fpmlb	12	1	The	the	DT
cord-017784-4r3fpmlb	12	2	term	term	NN
cord-017784-4r3fpmlb	12	3	refers	refer	VBZ
cord-017784-4r3fpmlb	12	4	to	to	IN
cord-017784-4r3fpmlb	12	5	the	the	DT
cord-017784-4r3fpmlb	12	6	inability	inability	NN
cord-017784-4r3fpmlb	12	7	to	to	TO
cord-017784-4r3fpmlb	12	8	perform	perform	VB
cord-017784-4r3fpmlb	12	9	adequately	adequately	RB
cord-017784-4r3fpmlb	12	10	the	the	DT
cord-017784-4r3fpmlb	12	11	fundamental	fundamental	JJ
cord-017784-4r3fpmlb	12	12	functions	function	NNS
cord-017784-4r3fpmlb	12	13	of	of	IN
cord-017784-4r3fpmlb	12	14	respiration	respiration	NN
cord-017784-4r3fpmlb	12	15	:	:	:
cord-017784-4r3fpmlb	12	16	to	to	TO
cord-017784-4r3fpmlb	12	17	deliver	deliver	VB
cord-017784-4r3fpmlb	12	18	oxygen	oxygen	NN
cord-017784-4r3fpmlb	12	19	to	to	IN
cord-017784-4r3fpmlb	12	20	the	the	DT
cord-017784-4r3fpmlb	12	21	blood	blood	NN
cord-017784-4r3fpmlb	12	22	and	and	CC
cord-017784-4r3fpmlb	12	23	to	to	TO
cord-017784-4r3fpmlb	12	24	eliminate	eliminate	VB
cord-017784-4r3fpmlb	12	25	carbon	carbon	NN
cord-017784-4r3fpmlb	12	26	dioxide	dioxide	NN
cord-017784-4r3fpmlb	12	27	from	from	IN
cord-017784-4r3fpmlb	12	28	it	-PRON-	PRP
cord-017784-4r3fpmlb	12	29	.	.	.
cord-017784-4r3fpmlb	13	1	Respiratory	respiratory	JJ
cord-017784-4r3fpmlb	13	2	failure	failure	NN
cord-017784-4r3fpmlb	13	3	has	have	VBZ
cord-017784-4r3fpmlb	13	4	many	many	JJ
cord-017784-4r3fpmlb	13	5	causes	cause	NNS
cord-017784-4r3fpmlb	13	6	and	and	CC
cord-017784-4r3fpmlb	13	7	can	can	MD
cord-017784-4r3fpmlb	13	8	come	come	VB
cord-017784-4r3fpmlb	13	9	on	on	RP
cord-017784-4r3fpmlb	13	10	abruptly	abruptly	RB
cord-017784-4r3fpmlb	13	11	(	(	-LRB-
cord-017784-4r3fpmlb	13	12	acute	acute	JJ
cord-017784-4r3fpmlb	13	13	respiratory	respiratory	JJ
cord-017784-4r3fpmlb	13	14	failure	failure	NN
cord-017784-4r3fpmlb	13	15	)	)	-RRB-
cord-017784-4r3fpmlb	13	16	,	,	,
cord-017784-4r3fpmlb	13	17	when	when	WRB
cord-017784-4r3fpmlb	13	18	the	the	DT
cord-017784-4r3fpmlb	13	19	underlying	underlying	JJ
cord-017784-4r3fpmlb	13	20	cause	cause	NN
cord-017784-4r3fpmlb	13	21	progresses	progress	VBZ
cord-017784-4r3fpmlb	13	22	rapidly	rapidly	RB
cord-017784-4r3fpmlb	13	23	,	,	,
cord-017784-4r3fpmlb	13	24	or	or	CC
cord-017784-4r3fpmlb	13	25	slowly	slowly	RB
cord-017784-4r3fpmlb	13	26	(	(	-LRB-
cord-017784-4r3fpmlb	13	27	chronic	chronic	JJ
cord-017784-4r3fpmlb	13	28	respiratory	respiratory	JJ
cord-017784-4r3fpmlb	13	29	failure	failure	NN
cord-017784-4r3fpmlb	13	30	)	)	-RRB-
cord-017784-4r3fpmlb	13	31	,	,	,
cord-017784-4r3fpmlb	13	32	when	when	WRB
cord-017784-4r3fpmlb	13	33	it	-PRON-	PRP
cord-017784-4r3fpmlb	13	34	is	be	VBZ
cord-017784-4r3fpmlb	13	35	associated	associate	VBN
cord-017784-4r3fpmlb	13	36	over	over	IN
cord-017784-4r3fpmlb	13	37	months	month	NNS
cord-017784-4r3fpmlb	13	38	or	or	CC
cord-017784-4r3fpmlb	13	39	even	even	RB
cord-017784-4r3fpmlb	13	40	years	year	NNS
cord-017784-4r3fpmlb	13	41	with	with	IN
cord-017784-4r3fpmlb	13	42	a	a	DT
cord-017784-4r3fpmlb	13	43	progressive	progressive	JJ
cord-017784-4r3fpmlb	13	44	underlying	underlying	JJ
cord-017784-4r3fpmlb	13	45	process	process	NN
cord-017784-4r3fpmlb	13	46	.	.	.
cord-017784-4r3fpmlb	14	1	Triggering	trigger	VBG
cord-017784-4r3fpmlb	14	2	causes	cause	NNS
cord-017784-4r3fpmlb	14	3	of	of	IN
cord-017784-4r3fpmlb	14	4	ARF	arf	NN
cord-017784-4r3fpmlb	14	5	in	in	IN
cord-017784-4r3fpmlb	14	6	advanced	advanced	JJ
cord-017784-4r3fpmlb	14	7	aged	aged	JJ
cord-017784-4r3fpmlb	14	8	patients	patient	NNS
cord-017784-4r3fpmlb	14	9	are	be	VBP
cord-017784-4r3fpmlb	14	10	especially	especially	RB
cord-017784-4r3fpmlb	14	11	acute	acute	JJ
cord-017784-4r3fpmlb	14	12	heart	heart	NN
cord-017784-4r3fpmlb	14	13	decompensation	decompensation	NN
cord-017784-4r3fpmlb	14	14	,	,	,
cord-017784-4r3fpmlb	14	15	severe	severe	JJ
cord-017784-4r3fpmlb	14	16	community	community	NN
cord-017784-4r3fpmlb	14	17	-	-	HYPH
cord-017784-4r3fpmlb	14	18	acquired	acquire	VBN
cord-017784-4r3fpmlb	14	19	pneumonia	pneumonia	NN
cord-017784-4r3fpmlb	14	20	(	(	-LRB-
cord-017784-4r3fpmlb	14	21	CAP	CAP	NNP
cord-017784-4r3fpmlb	14	22	)	)	-RRB-
cord-017784-4r3fpmlb	14	23	,	,	,
cord-017784-4r3fpmlb	14	24	acute	acute	JJ
cord-017784-4r3fpmlb	14	25	exacerbations	exacerbation	NNS
cord-017784-4r3fpmlb	14	26	of	of	IN
cord-017784-4r3fpmlb	14	27	COPD	COPD	NNP
cord-017784-4r3fpmlb	14	28	(	(	-LRB-
cord-017784-4r3fpmlb	14	29	AECOPD	AECOPD	NNP
cord-017784-4r3fpmlb	14	30	)	)	-RRB-
cord-017784-4r3fpmlb	14	31	,	,	,
cord-017784-4r3fpmlb	14	32	and	and	CC
cord-017784-4r3fpmlb	14	33	pulmonary	pulmonary	JJ
cord-017784-4r3fpmlb	14	34	embolism	embolism	NN
cord-017784-4r3fpmlb	14	35	.	.	.
cord-017784-4r3fpmlb	15	1	Pneumothorax	pneumothorax	NN
cord-017784-4r3fpmlb	15	2	,	,	,
cord-017784-4r3fpmlb	15	3	lung	lung	NN
cord-017784-4r3fpmlb	15	4	cancer	cancer	NN
cord-017784-4r3fpmlb	15	5	,	,	,
cord-017784-4r3fpmlb	15	6	severe	severe	JJ
cord-017784-4r3fpmlb	15	7	sepsis	sepsis	NN
cord-017784-4r3fpmlb	15	8	,	,	,
cord-017784-4r3fpmlb	15	9	and	and	CC
cord-017784-4r3fpmlb	15	10	acute	acute	JJ
cord-017784-4r3fpmlb	15	11	asthma	asthma	NN
cord-017784-4r3fpmlb	15	12	were	be	VBD
cord-017784-4r3fpmlb	15	13	less	less	RBR
cord-017784-4r3fpmlb	15	14	frequent	frequent	JJ
cord-017784-4r3fpmlb	15	15	(	(	-LRB-
cord-017784-4r3fpmlb	15	16	<	<	XX
cord-017784-4r3fpmlb	15	17	5	5	CD
cord-017784-4r3fpmlb	15	18	%	%	NN
cord-017784-4r3fpmlb	15	19	)	)	-RRB-
cord-017784-4r3fpmlb	16	1	[	[	-LRB-
cord-017784-4r3fpmlb	16	2	2	2	CD
cord-017784-4r3fpmlb	16	3	]	]	-RRB-
cord-017784-4r3fpmlb	16	4	.	.	.
cord-017784-4r3fpmlb	17	1	Acute	acute	JJ
cord-017784-4r3fpmlb	17	2	respiratory	respiratory	JJ
cord-017784-4r3fpmlb	17	3	failure	failure	NN
cord-017784-4r3fpmlb	17	4	is	be	VBZ
cord-017784-4r3fpmlb	17	5	a	a	DT
cord-017784-4r3fpmlb	17	6	condition	condition	NN
cord-017784-4r3fpmlb	17	7	in	in	IN
cord-017784-4r3fpmlb	17	8	which	which	WDT
cord-017784-4r3fpmlb	17	9	the	the	DT
cord-017784-4r3fpmlb	17	10	respiratory	respiratory	JJ
cord-017784-4r3fpmlb	17	11	system	system	NN
cord-017784-4r3fpmlb	17	12	fails	fail	VBZ
cord-017784-4r3fpmlb	17	13	in	in	IN
cord-017784-4r3fpmlb	17	14	one	one	CD
cord-017784-4r3fpmlb	17	15	or	or	CC
cord-017784-4r3fpmlb	17	16	both	both	DT
cord-017784-4r3fpmlb	17	17	of	of	IN
cord-017784-4r3fpmlb	17	18	its	-PRON-	PRP$
cord-017784-4r3fpmlb	17	19	gas	gas	NN
cord-017784-4r3fpmlb	17	20	functions	function	NNS
cord-017784-4r3fpmlb	17	21	,	,	,
cord-017784-4r3fpmlb	17	22	i.e.	i.e.	FW
cord-017784-4r3fpmlb	17	23	,	,	,
cord-017784-4r3fpmlb	17	24	oxygenation	oxygenation	NN
cord-017784-4r3fpmlb	17	25	(	(	-LRB-
cord-017784-4r3fpmlb	17	26	PaO	pao	NN
cord-017784-4r3fpmlb	17	27	2	2	CD
cord-017784-4r3fpmlb	17	28	<	<	XX
cord-017784-4r3fpmlb	17	29	60	60	CD
cord-017784-4r3fpmlb	17	30	mmHg	mmHg	NNS
cord-017784-4r3fpmlb	17	31	)	)	-RRB-
cord-017784-4r3fpmlb	17	32	of	of	IN
cord-017784-4r3fpmlb	17	33	and/or	and/or	CC
cord-017784-4r3fpmlb	17	34	elimination	elimination	NN
cord-017784-4r3fpmlb	17	35	of	of	IN
cord-017784-4r3fpmlb	17	36	carbon	carbon	NN
cord-017784-4r3fpmlb	17	37	dioxide	dioxide	NN
cord-017784-4r3fpmlb	17	38	(	(	-LRB-
cord-017784-4r3fpmlb	17	39	arterial	arterial	JJ
cord-017784-4r3fpmlb	17	40	carbon	carbon	NN
cord-017784-4r3fpmlb	17	41	dioxide	dioxide	NN
cord-017784-4r3fpmlb	17	42	tension	tension	NN
cord-017784-4r3fpmlb	17	43	(	(	-LRB-
cord-017784-4r3fpmlb	17	44	PaCO	paco	NN
cord-017784-4r3fpmlb	17	45	2	2	CD
cord-017784-4r3fpmlb	17	46	)	)	-RRB-
cord-017784-4r3fpmlb	17	47	>	>	NFP
cord-017784-4r3fpmlb	17	48	45	45	CD
cord-017784-4r3fpmlb	17	49	mmHg	mmHg	NNS
cord-017784-4r3fpmlb	17	50	)	)	-RRB-
cord-017784-4r3fpmlb	17	51	.	.	.
cord-017784-4r3fpmlb	18	1	In	in	IN
cord-017784-4r3fpmlb	18	2	practice	practice	NN
cord-017784-4r3fpmlb	18	3	,	,	,
cord-017784-4r3fpmlb	18	4	it	-PRON-	PRP
cord-017784-4r3fpmlb	18	5	may	may	MD
cord-017784-4r3fpmlb	18	6	be	be	VB
cord-017784-4r3fpmlb	18	7	classified	classify	VBN
cord-017784-4r3fpmlb	18	8	as	as	IN
cord-017784-4r3fpmlb	18	9	either	either	DT
cord-017784-4r3fpmlb	18	10	hypoxemic	hypoxemic	NNP
cord-017784-4r3fpmlb	18	11	or	or	CC
cord-017784-4r3fpmlb	18	12	hypercapnic	hypercapnic	NNP
cord-017784-4r3fpmlb	18	13	.	.	.
cord-017784-4r3fpmlb	19	1	Hypoxemic	hypoxemic	JJ
cord-017784-4r3fpmlb	19	2	respiratory	respiratory	JJ
cord-017784-4r3fpmlb	19	3	failure	failure	NN
cord-017784-4r3fpmlb	19	4	(	(	-LRB-
cord-017784-4r3fpmlb	19	5	type	type	NN
cord-017784-4r3fpmlb	19	6	I	i	NN
cord-017784-4r3fpmlb	19	7	)	)	-RRB-
cord-017784-4r3fpmlb	19	8	is	be	VBZ
cord-017784-4r3fpmlb	19	9	characterized	characterize	VBN
cord-017784-4r3fpmlb	19	10	by	by	IN
cord-017784-4r3fpmlb	19	11	an	an	DT
cord-017784-4r3fpmlb	19	12	arterial	arterial	JJ
cord-017784-4r3fpmlb	19	13	oxygen	oxygen	NN
cord-017784-4r3fpmlb	19	14	tension	tension	NN
cord-017784-4r3fpmlb	19	15	(	(	-LRB-
cord-017784-4r3fpmlb	19	16	PaO	PaO	NNP
cord-017784-4r3fpmlb	19	17	2	2	CD
cord-017784-4r3fpmlb	19	18	)	)	-RRB-
cord-017784-4r3fpmlb	20	1	lower	low	JJR
cord-017784-4r3fpmlb	20	2	than	than	IN
cord-017784-4r3fpmlb	20	3	60	60	CD
cord-017784-4r3fpmlb	20	4	mm	mm	NN
cord-017784-4r3fpmlb	20	5	Hg	hg	NN
cord-017784-4r3fpmlb	20	6	with	with	IN
cord-017784-4r3fpmlb	20	7	a	a	DT
cord-017784-4r3fpmlb	20	8	normal	normal	JJ
cord-017784-4r3fpmlb	20	9	or	or	CC
cord-017784-4r3fpmlb	20	10	low	low	JJ
cord-017784-4r3fpmlb	20	11	arterial	arterial	JJ
cord-017784-4r3fpmlb	20	12	carbon	carbon	NN
cord-017784-4r3fpmlb	20	13	dioxide	dioxide	NN
cord-017784-4r3fpmlb	20	14	tension	tension	NN
cord-017784-4r3fpmlb	20	15	(	(	-LRB-
cord-017784-4r3fpmlb	20	16	PaCO	paco	NN
cord-017784-4r3fpmlb	20	17	2	2	CD
cord-017784-4r3fpmlb	20	18	)	)	-RRB-
cord-017784-4r3fpmlb	20	19	.	.	.
cord-017784-4r3fpmlb	21	1	This	this	DT
cord-017784-4r3fpmlb	21	2	is	be	VBZ
cord-017784-4r3fpmlb	21	3	the	the	DT
cord-017784-4r3fpmlb	21	4	most	most	RBS
cord-017784-4r3fpmlb	21	5	common	common	JJ
cord-017784-4r3fpmlb	21	6	form	form	NN
cord-017784-4r3fpmlb	21	7	of	of	IN
cord-017784-4r3fpmlb	21	8	respiratory	respiratory	JJ
cord-017784-4r3fpmlb	21	9	failure	failure	NN
cord-017784-4r3fpmlb	21	10	,	,	,
cord-017784-4r3fpmlb	21	11	and	and	CC
cord-017784-4r3fpmlb	21	12	it	-PRON-	PRP
cord-017784-4r3fpmlb	21	13	can	can	MD
cord-017784-4r3fpmlb	21	14	be	be	VB
cord-017784-4r3fpmlb	21	15	associated	associate	VBN
cord-017784-4r3fpmlb	21	16	with	with	IN
cord-017784-4r3fpmlb	21	17	virtually	virtually	RB
cord-017784-4r3fpmlb	21	18	all	all	DT
cord-017784-4r3fpmlb	21	19	acute	acute	JJ
cord-017784-4r3fpmlb	21	20	diseases	disease	NNS
cord-017784-4r3fpmlb	21	21	of	of	IN
cord-017784-4r3fpmlb	21	22	the	the	DT
cord-017784-4r3fpmlb	21	23	lung	lung	NN
cord-017784-4r3fpmlb	21	24	,	,	,
cord-017784-4r3fpmlb	21	25	which	which	WDT
cord-017784-4r3fpmlb	21	26	generally	generally	RB
cord-017784-4r3fpmlb	21	27	involve	involve	VBP
cord-017784-4r3fpmlb	21	28	fluid	fluid	NN
cord-017784-4r3fpmlb	21	29	filling	filling	NN
cord-017784-4r3fpmlb	21	30	or	or	CC
cord-017784-4r3fpmlb	21	31	collapse	collapse	NN
cord-017784-4r3fpmlb	21	32	of	of	IN
cord-017784-4r3fpmlb	21	33	alveolar	alveolar	JJ
cord-017784-4r3fpmlb	21	34	units	unit	NNS
cord-017784-4r3fpmlb	21	35	.	.	.
cord-017784-4r3fpmlb	22	1	The	the	DT
cord-017784-4r3fpmlb	22	2	four	four	CD
cord-017784-4r3fpmlb	22	3	pathophysiological	pathophysiological	JJ
cord-017784-4r3fpmlb	22	4	mechanisms	mechanism	NNS
cord-017784-4r3fpmlb	22	5	related	relate	VBN
cord-017784-4r3fpmlb	22	6	to	to	IN
cord-017784-4r3fpmlb	22	7	hypoxemic	hypoxemic	NNP
cord-017784-4r3fpmlb	22	8	ARF	ARF	NNP
cord-017784-4r3fpmlb	22	9	are	be	VBP
cord-017784-4r3fpmlb	22	10	[	[	-LRB-
cord-017784-4r3fpmlb	22	11	3	3	CD
cord-017784-4r3fpmlb	22	12	,	,	,
cord-017784-4r3fpmlb	22	13	4	4	CD
cord-017784-4r3fpmlb	22	14	]	]	-RRB-
cord-017784-4r3fpmlb	22	15	:	:	:
cord-017784-4r3fpmlb	23	1	1	1	LS
cord-017784-4r3fpmlb	23	2	.	.	.
cord-017784-4r3fpmlb	24	1	Ventilation	ventilation	NN
cord-017784-4r3fpmlb	24	2	/	/	SYM
cord-017784-4r3fpmlb	24	3	perfusion	perfusion	NN
cord-017784-4r3fpmlb	24	4	inequality	inequality	NN
cord-017784-4r3fpmlb	24	5	which	which	WDT
cord-017784-4r3fpmlb	24	6	is	be	VBZ
cord-017784-4r3fpmlb	24	7	the	the	DT
cord-017784-4r3fpmlb	24	8	main	main	JJ
cord-017784-4r3fpmlb	24	9	mechanisms	mechanism	NNS
cord-017784-4r3fpmlb	24	10	in	in	IN
cord-017784-4r3fpmlb	24	11	an	an	DT
cord-017784-4r3fpmlb	24	12	emergency	emergency	NN
cord-017784-4r3fpmlb	24	13	setting	set	VBG
cord-017784-4r3fpmlb	24	14	(	(	-LRB-
cord-017784-4r3fpmlb	24	15	congestive	congestive	JJ
cord-017784-4r3fpmlb	24	16	heart	heart	NN
cord-017784-4r3fpmlb	24	17	failure	failure	NN
cord-017784-4r3fpmlb	24	18	or	or	CC
cord-017784-4r3fpmlb	24	19	pneumonia	pneumonia	NN
cord-017784-4r3fpmlb	24	20	)	)	-RRB-
cord-017784-4r3fpmlb	24	21	2	2	CD
cord-017784-4r3fpmlb	24	22	.	.	.
cord-017784-4r3fpmlb	25	1	Increased	increased	JJ
cord-017784-4r3fpmlb	25	2	shunt	shunt	NN
cord-017784-4r3fpmlb	25	3	(	(	-LRB-
cord-017784-4r3fpmlb	25	4	acute	acute	JJ
cord-017784-4r3fpmlb	25	5	respiratory	respiratory	JJ
cord-017784-4r3fpmlb	25	6	distress	distress	NN
cord-017784-4r3fpmlb	25	7	syndrome	syndrome	NN
cord-017784-4r3fpmlb	25	8	)	)	-RRB-
cord-017784-4r3fpmlb	25	9	3	3	CD
cord-017784-4r3fpmlb	25	10	.	.	.
cord-017784-4r3fpmlb	26	1	Alveolar	alveolar	JJ
cord-017784-4r3fpmlb	26	2	hypoventilation	hypoventilation	NN
cord-017784-4r3fpmlb	26	3	(	(	-LRB-
cord-017784-4r3fpmlb	26	4	chronic	chronic	JJ
cord-017784-4r3fpmlb	26	5	obstructive	obstructive	JJ
cord-017784-4r3fpmlb	26	6	pulmonary	pulmonary	JJ
cord-017784-4r3fpmlb	26	7	disease	disease	NN
cord-017784-4r3fpmlb	26	8	)	)	-RRB-
cord-017784-4r3fpmlb	26	9	4	4	CD
cord-017784-4r3fpmlb	26	10	.	.	.
cord-017784-4r3fpmlb	27	1	Diffusion	diffusion	NN
cord-017784-4r3fpmlb	27	2	impairment	impairment	NN
cord-017784-4r3fpmlb	27	3	(	(	-LRB-
cord-017784-4r3fpmlb	27	4	pulmonary	pulmonary	JJ
cord-017784-4r3fpmlb	27	5	fibrosis	fibrosis	NN
cord-017784-4r3fpmlb	27	6	)	)	-RRB-
cord-017784-4r3fpmlb	28	1	Hypercapnic	Hypercapnic	NNP
cord-017784-4r3fpmlb	28	2	respiratory	respiratory	JJ
cord-017784-4r3fpmlb	28	3	failure	failure	NN
cord-017784-4r3fpmlb	28	4	(	(	-LRB-
cord-017784-4r3fpmlb	28	5	type	type	NN
cord-017784-4r3fpmlb	28	6	II	II	NNP
cord-017784-4r3fpmlb	28	7	)	)	-RRB-
cord-017784-4r3fpmlb	28	8	is	be	VBZ
cord-017784-4r3fpmlb	28	9	characterized	characterize	VBN
cord-017784-4r3fpmlb	28	10	by	by	IN
cord-017784-4r3fpmlb	28	11	a	a	DT
cord-017784-4r3fpmlb	28	12	PaCO	paco	NN
cord-017784-4r3fpmlb	28	13	2	2	CD
cord-017784-4r3fpmlb	28	14	higher	high	JJR
cord-017784-4r3fpmlb	28	15	than	than	IN
cord-017784-4r3fpmlb	28	16	45	45	CD
cord-017784-4r3fpmlb	28	17	mmHg	mmHg	NNS
cord-017784-4r3fpmlb	28	18	.	.	.
cord-017784-4r3fpmlb	28	19	Hypoxemia	Hypoxemia	NNP
cord-017784-4r3fpmlb	28	20	is	be	VBZ
cord-017784-4r3fpmlb	28	21	common	common	JJ
cord-017784-4r3fpmlb	28	22	in	in	IN
cord-017784-4r3fpmlb	28	23	patients	patient	NNS
cord-017784-4r3fpmlb	28	24	with	with	IN
cord-017784-4r3fpmlb	28	25	hypercapnic	hypercapnic	NNP
cord-017784-4r3fpmlb	28	26	respiratory	respiratory	JJ
cord-017784-4r3fpmlb	28	27	failure	failure	NN
cord-017784-4r3fpmlb	28	28	who	who	WP
cord-017784-4r3fpmlb	28	29	are	be	VBP
cord-017784-4r3fpmlb	28	30	breathing	breathe	VBG
cord-017784-4r3fpmlb	28	31	room	room	NN
cord-017784-4r3fpmlb	28	32	air	air	NN
cord-017784-4r3fpmlb	28	33	.	.	.
cord-017784-4r3fpmlb	29	1	Common	common	JJ
cord-017784-4r3fpmlb	29	2	etiologies	etiology	NNS
cord-017784-4r3fpmlb	29	3	include	include	VBP
cord-017784-4r3fpmlb	29	4	drug	drug	NN
cord-017784-4r3fpmlb	29	5	overdose	overdose	NN
cord-017784-4r3fpmlb	29	6	,	,	,
cord-017784-4r3fpmlb	29	7	neuromuscular	neuromuscular	JJ
cord-017784-4r3fpmlb	29	8	disease	disease	NN
cord-017784-4r3fpmlb	29	9	,	,	,
cord-017784-4r3fpmlb	29	10	chest	chest	NN
cord-017784-4r3fpmlb	29	11	wall	wall	NN
cord-017784-4r3fpmlb	29	12	abnormalities	abnormality	NNS
cord-017784-4r3fpmlb	29	13	,	,	,
cord-017784-4r3fpmlb	29	14	and	and	CC
cord-017784-4r3fpmlb	29	15	severe	severe	JJ
cord-017784-4r3fpmlb	29	16	airway	airway	NN
cord-017784-4r3fpmlb	29	17	disorders	disorder	NNS
cord-017784-4r3fpmlb	29	18	(	(	-LRB-
cord-017784-4r3fpmlb	29	19	e.g.	e.g.	RB
cord-017784-4r3fpmlb	29	20	,	,	,
cord-017784-4r3fpmlb	29	21	chronic	chronic	JJ
cord-017784-4r3fpmlb	29	22	obstructive	obstructive	JJ
cord-017784-4r3fpmlb	29	23	pulmonary	pulmonary	JJ
cord-017784-4r3fpmlb	29	24	disease	disease	NN
cord-017784-4r3fpmlb	29	25	)	)	-RRB-
cord-017784-4r3fpmlb	29	26	.	.	.
cord-017784-4r3fpmlb	30	1	In	in	IN
cord-017784-4r3fpmlb	30	2	case	case	NN
cord-017784-4r3fpmlb	30	3	of	of	IN
cord-017784-4r3fpmlb	30	4	a	a	DT
cord-017784-4r3fpmlb	30	5	COPD	COPD	NNP
cord-017784-4r3fpmlb	30	6	exacerbation	exacerbation	NN
cord-017784-4r3fpmlb	30	7	,	,	,
cord-017784-4r3fpmlb	30	8	an	an	DT
cord-017784-4r3fpmlb	30	9	acute	acute	JJ
cord-017784-4r3fpmlb	30	10	inflammation	inflammation	NN
cord-017784-4r3fpmlb	30	11	in	in	IN
cord-017784-4r3fpmlb	30	12	the	the	DT
cord-017784-4r3fpmlb	30	13	airways	airways	NNP
cord-017784-4r3fpmlb	30	14	increases	increase	VBZ
cord-017784-4r3fpmlb	30	15	resistance	resistance	NN
cord-017784-4r3fpmlb	30	16	to	to	IN
cord-017784-4r3fpmlb	30	17	air	air	NN
cord-017784-4r3fpmlb	30	18	flow	flow	NN
cord-017784-4r3fpmlb	30	19	with	with	IN
cord-017784-4r3fpmlb	30	20	consequent	consequent	JJ
cord-017784-4r3fpmlb	30	21	air	air	NN
cord-017784-4r3fpmlb	30	22	trapping	trapping	NN
cord-017784-4r3fpmlb	30	23	.	.	.
cord-017784-4r3fpmlb	31	1	Increased	increase	VBN
cord-017784-4r3fpmlb	31	2	resistance	resistance	NN
cord-017784-4r3fpmlb	31	3	and	and	CC
cord-017784-4r3fpmlb	31	4	elastic	elastic	JJ
cord-017784-4r3fpmlb	31	5	load	load	NN
cord-017784-4r3fpmlb	31	6	due	due	JJ
cord-017784-4r3fpmlb	31	7	to	to	IN
cord-017784-4r3fpmlb	31	8	air	air	NN
cord-017784-4r3fpmlb	31	9	trapping	trapping	NN
cord-017784-4r3fpmlb	31	10	place	place	NN
cord-017784-4r3fpmlb	31	11	respiratory	respiratory	JJ
cord-017784-4r3fpmlb	31	12	muscles	muscle	NNS
cord-017784-4r3fpmlb	31	13	at	at	IN
cord-017784-4r3fpmlb	31	14	a	a	DT
cord-017784-4r3fpmlb	31	15	mechanical	mechanical	JJ
cord-017784-4r3fpmlb	31	16	disadvantage	disadvantage	NN
cord-017784-4r3fpmlb	31	17	and	and	CC
cord-017784-4r3fpmlb	31	18	increases	increase	VBZ
cord-017784-4r3fpmlb	31	19	the	the	DT
cord-017784-4r3fpmlb	31	20	work	work	NN
cord-017784-4r3fpmlb	31	21	of	of	IN
cord-017784-4r3fpmlb	31	22	breathing	breathing	NN
cord-017784-4r3fpmlb	31	23	and	and	CC
cord-017784-4r3fpmlb	31	24	leads	lead	VBZ
cord-017784-4r3fpmlb	31	25	to	to	IN
cord-017784-4r3fpmlb	31	26	ARF	ARF	NNP
cord-017784-4r3fpmlb	31	27	.	.	.
cord-017784-4r3fpmlb	32	1	Infectious	infectious	JJ
cord-017784-4r3fpmlb	32	2	factor	factor	NN
cord-017784-4r3fpmlb	32	3	such	such	JJ
cord-017784-4r3fpmlb	32	4	as	as	IN
cord-017784-4r3fpmlb	32	5	pneumonia	pneumonia	NN
cord-017784-4r3fpmlb	32	6	with	with	IN
cord-017784-4r3fpmlb	32	7	/	/	SYM
cord-017784-4r3fpmlb	32	8	without	without	IN
cord-017784-4r3fpmlb	32	9	sepsis	sepsis	NN
cord-017784-4r3fpmlb	32	10	caused	cause	VBN
cord-017784-4r3fpmlb	32	11	by	by	IN
cord-017784-4r3fpmlb	32	12	a	a	DT
cord-017784-4r3fpmlb	32	13	variety	variety	NN
cord-017784-4r3fpmlb	32	14	of	of	IN
cord-017784-4r3fpmlb	32	15	pathogens	pathogen	NNS
cord-017784-4r3fpmlb	32	16	,	,	,
cord-017784-4r3fpmlb	32	17	including	include	VBG
cord-017784-4r3fpmlb	32	18	bacteria	bacteria	NNS
cord-017784-4r3fpmlb	32	19	,	,	,
cord-017784-4r3fpmlb	32	20	viruses	virus	NNS
cord-017784-4r3fpmlb	32	21	,	,	,
cord-017784-4r3fpmlb	32	22	malaria	malaria	NN
cord-017784-4r3fpmlb	32	23	,	,	,
cord-017784-4r3fpmlb	32	24	and	and	CC
cord-017784-4r3fpmlb	32	25	fungal	fungal	NN
cord-017784-4r3fpmlb	32	26	is	be	VBZ
cord-017784-4r3fpmlb	32	27	the	the	DT
cord-017784-4r3fpmlb	32	28	medical	medical	JJ
cord-017784-4r3fpmlb	32	29	condition	condition	NN
cord-017784-4r3fpmlb	32	30	that	that	WDT
cord-017784-4r3fpmlb	32	31	is	be	VBZ
cord-017784-4r3fpmlb	32	32	most	most	RBS
cord-017784-4r3fpmlb	32	33	commonly	commonly	RB
cord-017784-4r3fpmlb	32	34	associated	associate	VBN
cord-017784-4r3fpmlb	32	35	with	with	IN
cord-017784-4r3fpmlb	32	36	acute	acute	JJ
cord-017784-4r3fpmlb	32	37	respiratory	respiratory	JJ
cord-017784-4r3fpmlb	32	38	distress	distress	NN
cord-017784-4r3fpmlb	32	39	syndrome	syndrome	NN
cord-017784-4r3fpmlb	32	40	(	(	-LRB-
cord-017784-4r3fpmlb	32	41	ARDS	ARDS	NNP
cord-017784-4r3fpmlb	32	42	)	)	-RRB-
cord-017784-4r3fpmlb	32	43	.	.	.
cord-017784-4r3fpmlb	33	1	Sepsis	sepsis	NN
cord-017784-4r3fpmlb	33	2	due	due	IN
cord-017784-4r3fpmlb	33	3	to	to	IN
cord-017784-4r3fpmlb	33	4	nonpulmonary	nonpulmonary	JJ
cord-017784-4r3fpmlb	33	5	infections	infection	NNS
cord-017784-4r3fpmlb	33	6	,	,	,
cord-017784-4r3fpmlb	33	7	aspiration	aspiration	NN
cord-017784-4r3fpmlb	33	8	of	of	IN
cord-017784-4r3fpmlb	33	9	gastric	gastric	JJ
cord-017784-4r3fpmlb	33	10	contents	content	NNS
cord-017784-4r3fpmlb	33	11	,	,	,
cord-017784-4r3fpmlb	33	12	and	and	CC
cord-017784-4r3fpmlb	33	13	major	major	JJ
cord-017784-4r3fpmlb	33	14	trauma	trauma	NN
cord-017784-4r3fpmlb	33	15	with	with	IN
cord-017784-4r3fpmlb	33	16	shock	shock	NN
cord-017784-4r3fpmlb	33	17	also	also	RB
cord-017784-4r3fpmlb	33	18	commonly	commonly	RB
cord-017784-4r3fpmlb	33	19	precipitate	precipitate	VBP
cord-017784-4r3fpmlb	33	20	the	the	DT
cord-017784-4r3fpmlb	33	21	injury	injury	NN
cord-017784-4r3fpmlb	33	22	[	[	-LRB-
cord-017784-4r3fpmlb	33	23	5	5	CD
cord-017784-4r3fpmlb	33	24	]	]	-RRB-
cord-017784-4r3fpmlb	33	25	.	.	.
cord-017784-4r3fpmlb	34	1	Since	since	IN
cord-017784-4r3fpmlb	34	2	the	the	DT
cord-017784-4r3fpmlb	34	3	same	same	JJ
cord-017784-4r3fpmlb	34	4	kinds	kind	NNS
cord-017784-4r3fpmlb	34	5	of	of	IN
cord-017784-4r3fpmlb	34	6	immune	immune	JJ
cord-017784-4r3fpmlb	34	7	cells	cell	NNS
cord-017784-4r3fpmlb	34	8	and	and	CC
cord-017784-4r3fpmlb	34	9	immune	immune	JJ
cord-017784-4r3fpmlb	34	10	proteins	protein	NNS
cord-017784-4r3fpmlb	34	11	,	,	,
cord-017784-4r3fpmlb	34	12	including	include	VBG
cord-017784-4r3fpmlb	34	13	immunoglobulins	immunoglobulin	NNS
cord-017784-4r3fpmlb	34	14	and	and	CC
cord-017784-4r3fpmlb	34	15	complements	complement	NNS
cord-017784-4r3fpmlb	34	16	,	,	,
cord-017784-4r3fpmlb	34	17	are	be	VBP
cord-017784-4r3fpmlb	34	18	observed	observe	VBN
cord-017784-4r3fpmlb	34	19	in	in	IN
cord-017784-4r3fpmlb	34	20	the	the	DT
cord-017784-4r3fpmlb	34	21	pathologic	pathologic	JJ
cord-017784-4r3fpmlb	34	22	lesions	lesion	NNS
cord-017784-4r3fpmlb	34	23	of	of	IN
cord-017784-4r3fpmlb	34	24	pneumonia	pneumonia	NN
cord-017784-4r3fpmlb	34	25	,	,	,
cord-017784-4r3fpmlb	34	26	ARDS	ARDS	NNP
cord-017784-4r3fpmlb	34	27	,	,	,
cord-017784-4r3fpmlb	34	28	and	and	CC
cord-017784-4r3fpmlb	34	29	other	other	JJ
cord-017784-4r3fpmlb	34	30	organ	organ	NN
cord-017784-4r3fpmlb	34	31	-	-	HYPH
cord-017784-4r3fpmlb	34	32	specific	specific	JJ
cord-017784-4r3fpmlb	34	33	pathologic	pathologic	JJ
cord-017784-4r3fpmlb	34	34	lesions	lesion	NNS
cord-017784-4r3fpmlb	34	35	,	,	,
cord-017784-4r3fpmlb	34	36	it	-PRON-	PRP
cord-017784-4r3fpmlb	34	37	may	may	MD
cord-017784-4r3fpmlb	34	38	be	be	VB
cord-017784-4r3fpmlb	34	39	a	a	DT
cord-017784-4r3fpmlb	34	40	reasonable	reasonable	JJ
cord-017784-4r3fpmlb	34	41	assumption	assumption	NN
cord-017784-4r3fpmlb	34	42	that	that	IN
cord-017784-4r3fpmlb	34	43	sepsis	sepsis	NN
cord-017784-4r3fpmlb	34	44	and	and	CC
cord-017784-4r3fpmlb	34	45	ARDS	ARDS	NNP
cord-017784-4r3fpmlb	34	46	have	have	VBP
cord-017784-4r3fpmlb	34	47	similar	similar	JJ
cord-017784-4r3fpmlb	34	48	underlying	underlying	JJ
cord-017784-4r3fpmlb	34	49	mechanisms	mechanism	NNS
cord-017784-4r3fpmlb	34	50	,	,	,
cord-017784-4r3fpmlb	34	51	characterized	characterize	VBN
cord-017784-4r3fpmlb	34	52	by	by	IN
cord-017784-4r3fpmlb	34	53	inflammation	inflammation	NN
cord-017784-4r3fpmlb	34	54	and	and	CC
cord-017784-4r3fpmlb	34	55	endothelial	endothelial	JJ
cord-017784-4r3fpmlb	34	56	dysfunction	dysfunction	NN
cord-017784-4r3fpmlb	34	57	[	[	-LRB-
cord-017784-4r3fpmlb	34	58	6	6	CD
cord-017784-4r3fpmlb	34	59	]	]	-RRB-
cord-017784-4r3fpmlb	34	60	.	.	.
cord-017784-4r3fpmlb	35	1	ARDS	ARDS	NNP
cord-017784-4r3fpmlb	35	2	is	be	VBZ
cord-017784-4r3fpmlb	35	3	a	a	DT
cord-017784-4r3fpmlb	35	4	heterogeneous	heterogeneous	JJ
cord-017784-4r3fpmlb	35	5	syndrome	syndrome	NN
cord-017784-4r3fpmlb	35	6	characterized	characterize	VBN
cord-017784-4r3fpmlb	35	7	by	by	IN
cord-017784-4r3fpmlb	35	8	increased	increase	VBN
cord-017784-4r3fpmlb	35	9	permeability	permeability	NN
cord-017784-4r3fpmlb	35	10	of	of	IN
cord-017784-4r3fpmlb	35	11	pulmonary	pulmonary	JJ
cord-017784-4r3fpmlb	35	12	capillary	capillary	JJ
cord-017784-4r3fpmlb	35	13	endothelial	endothelial	JJ
cord-017784-4r3fpmlb	35	14	cells	cell	NNS
cord-017784-4r3fpmlb	35	15	and	and	CC
cord-017784-4r3fpmlb	35	16	alveolar	alveolar	JJ
cord-017784-4r3fpmlb	35	17	epithelial	epithelial	JJ
cord-017784-4r3fpmlb	35	18	cells	cell	NNS
cord-017784-4r3fpmlb	35	19	,	,	,
cord-017784-4r3fpmlb	35	20	leading	lead	VBG
cord-017784-4r3fpmlb	35	21	to	to	IN
cord-017784-4r3fpmlb	35	22	hypoxemia	hypoxemia	NN
cord-017784-4r3fpmlb	35	23	that	that	WDT
cord-017784-4r3fpmlb	35	24	is	be	VBZ
cord-017784-4r3fpmlb	35	25	refractory	refractory	JJ
cord-017784-4r3fpmlb	35	26	to	to	IN
cord-017784-4r3fpmlb	35	27	usual	usual	JJ
cord-017784-4r3fpmlb	35	28	oxygen	oxygen	NN
cord-017784-4r3fpmlb	35	29	therapy	therapy	NN
cord-017784-4r3fpmlb	35	30	[	[	-LRB-
cord-017784-4r3fpmlb	35	31	7	7	CD
cord-017784-4r3fpmlb	35	32	]	]	-RRB-
cord-017784-4r3fpmlb	35	33	.	.	.
cord-017784-4r3fpmlb	36	1	The	the	DT
cord-017784-4r3fpmlb	36	2	severity	severity	NN
cord-017784-4r3fpmlb	36	3	of	of	IN
cord-017784-4r3fpmlb	36	4	ARDS	ARDS	NNP
cord-017784-4r3fpmlb	36	5	is	be	VBZ
cord-017784-4r3fpmlb	36	6	associated	associate	VBN
cord-017784-4r3fpmlb	36	7	with	with	IN
cord-017784-4r3fpmlb	36	8	poor	poor	JJ
cord-017784-4r3fpmlb	36	9	prognosis	prognosis	NN
cord-017784-4r3fpmlb	36	10	and	and	CC
cord-017784-4r3fpmlb	36	11	higher	high	JJR
cord-017784-4r3fpmlb	36	12	mortality	mortality	NN
cord-017784-4r3fpmlb	36	13	,	,	,
cord-017784-4r3fpmlb	36	14	and	and	CC
cord-017784-4r3fpmlb	36	15	,	,	,
cord-017784-4r3fpmlb	36	16	by	by	IN
cord-017784-4r3fpmlb	36	17	the	the	DT
cord-017784-4r3fpmlb	36	18	Berlin	Berlin	NNP
cord-017784-4r3fpmlb	36	19	definition	definition	NN
cord-017784-4r3fpmlb	36	20	,	,	,
cord-017784-4r3fpmlb	36	21	diagnostic	diagnostic	JJ
cord-017784-4r3fpmlb	36	22	hypoxemia	hypoxemia	NN
cord-017784-4r3fpmlb	36	23	is	be	VBZ
cord-017784-4r3fpmlb	36	24	defined	define	VBN
cord-017784-4r3fpmlb	36	25	as	as	IN
cord-017784-4r3fpmlb	36	26	decreased	decrease	VBN
cord-017784-4r3fpmlb	36	27	arterial	arterial	JJ
cord-017784-4r3fpmlb	36	28	PaO	pao	JJ
cord-017784-4r3fpmlb	36	29	2	2	CD
cord-017784-4r3fpmlb	36	30	/FiO	/fio	SYM
cord-017784-4r3fpmlb	36	31	2	2	CD
cord-017784-4r3fpmlb	36	32	ratio	ratio	NN
cord-017784-4r3fpmlb	36	33	with	with	IN
cord-017784-4r3fpmlb	36	34	parameters	parameter	NNS
cord-017784-4r3fpmlb	36	35	of	of	IN
cord-017784-4r3fpmlb	36	36	201	201	CD
cord-017784-4r3fpmlb	36	37	-	-	SYM
cord-017784-4r3fpmlb	36	38	300	300	CD
cord-017784-4r3fpmlb	36	39	mmHg	mmHg	NNS
cord-017784-4r3fpmlb	36	40	for	for	IN
cord-017784-4r3fpmlb	36	41	mild	mild	JJ
cord-017784-4r3fpmlb	36	42	ARDS	ARDS	NNP
cord-017784-4r3fpmlb	36	43	,	,	,
cord-017784-4r3fpmlb	36	44	101	101	CD
cord-017784-4r3fpmlb	36	45	-	-	SYM
cord-017784-4r3fpmlb	36	46	200	200	CD
cord-017784-4r3fpmlb	36	47	mmHg	mmHg	NNS
cord-017784-4r3fpmlb	36	48	for	for	IN
cord-017784-4r3fpmlb	36	49	moderate	moderate	JJ
cord-017784-4r3fpmlb	36	50	ARDS	ARDS	NNP
cord-017784-4r3fpmlb	36	51	,	,	,
cord-017784-4r3fpmlb	36	52	and	and	CC
cord-017784-4r3fpmlb	36	53	<	<	XX
cord-017784-4r3fpmlb	36	54	100	100	CD
cord-017784-4r3fpmlb	36	55	mmHg	mmHg	NNS
cord-017784-4r3fpmlb	36	56	for	for	IN
cord-017784-4r3fpmlb	36	57	severe	severe	JJ
cord-017784-4r3fpmlb	36	58	ARDS	ARDS	NNP
cord-017784-4r3fpmlb	36	59	[	[	-LRB-
cord-017784-4r3fpmlb	36	60	8	8	CD
cord-017784-4r3fpmlb	36	61	]	]	-RRB-
cord-017784-4r3fpmlb	36	62	.	.	.
cord-017784-4r3fpmlb	37	1	Considering	consider	VBG
cord-017784-4r3fpmlb	37	2	the	the	DT
cord-017784-4r3fpmlb	37	3	immunopathogenesis	immunopathogenesis	NN
cord-017784-4r3fpmlb	37	4	of	of	IN
cord-017784-4r3fpmlb	37	5	pneumonia	pneumonia	NN
cord-017784-4r3fpmlb	37	6	,	,	,
cord-017784-4r3fpmlb	37	7	sepsis	sepsis	NN
cord-017784-4r3fpmlb	37	8	,	,	,
cord-017784-4r3fpmlb	37	9	and	and	CC
cord-017784-4r3fpmlb	37	10	ARDS	ARDS	NNP
cord-017784-4r3fpmlb	37	11	,	,	,
cord-017784-4r3fpmlb	37	12	early	early	JJ
cord-017784-4r3fpmlb	37	13	and	and	CC
cord-017784-4r3fpmlb	37	14	appropriate	appropriate	JJ
cord-017784-4r3fpmlb	37	15	antimicrobial	antimicrobial	JJ
cord-017784-4r3fpmlb	37	16	therapy	therapy	NN
cord-017784-4r3fpmlb	37	17	is	be	VBZ
cord-017784-4r3fpmlb	37	18	critical	critical	JJ
cord-017784-4r3fpmlb	37	19	to	to	TO
cord-017784-4r3fpmlb	37	20	reduce	reduce	VB
cord-017784-4r3fpmlb	37	21	the	the	DT
cord-017784-4r3fpmlb	37	22	number	number	NN
cord-017784-4r3fpmlb	37	23	of	of	IN
cord-017784-4r3fpmlb	37	24	pathogens	pathogen	NNS
cord-017784-4r3fpmlb	37	25	and	and	CC
cord-017784-4r3fpmlb	37	26	pathogen	pathogen	NN
cord-017784-4r3fpmlb	37	27	-	-	HYPH
cord-017784-4r3fpmlb	37	28	originated	originate	VBN
cord-017784-4r3fpmlb	37	29	substances	substance	NNS
cord-017784-4r3fpmlb	37	30	,	,	,
cord-017784-4r3fpmlb	37	31	thereby	thereby	RB
cord-017784-4r3fpmlb	37	32	inducing	induce	VBG
cord-017784-4r3fpmlb	37	33	early	early	JJ
cord-017784-4r3fpmlb	37	34	recovery	recovery	NN
cord-017784-4r3fpmlb	37	35	from	from	IN
cord-017784-4r3fpmlb	37	36	the	the	DT
cord-017784-4r3fpmlb	37	37	disease	disease	NN
cord-017784-4r3fpmlb	37	38	and	and	CC
cord-017784-4r3fpmlb	37	39	better	well	JJR
cord-017784-4r3fpmlb	37	40	outcome	outcome	NN
cord-017784-4r3fpmlb	37	41	.	.	.
cord-017784-4r3fpmlb	38	1	Similarly	similarly	RB
cord-017784-4r3fpmlb	38	2	,	,	,
cord-017784-4r3fpmlb	38	3	although	although	IN
cord-017784-4r3fpmlb	38	4	the	the	DT
cord-017784-4r3fpmlb	38	5	knowledge	knowledge	NN
cord-017784-4r3fpmlb	38	6	about	about	IN
cord-017784-4r3fpmlb	38	7	the	the	DT
cord-017784-4r3fpmlb	38	8	effectiveness	effectiveness	NN
cord-017784-4r3fpmlb	38	9	of	of	IN
cord-017784-4r3fpmlb	38	10	antibiotics	antibiotic	NNS
cord-017784-4r3fpmlb	38	11	in	in	IN
cord-017784-4r3fpmlb	38	12	the	the	DT
cord-017784-4r3fpmlb	38	13	management	management	NN
cord-017784-4r3fpmlb	38	14	of	of	IN
cord-017784-4r3fpmlb	38	15	acute	acute	JJ
cord-017784-4r3fpmlb	38	16	exacerbations	exacerbation	NNS
cord-017784-4r3fpmlb	38	17	of	of	IN
cord-017784-4r3fpmlb	38	18	COPD	COPD	NNP
cord-017784-4r3fpmlb	38	19	remains	remain	VBZ
cord-017784-4r3fpmlb	38	20	limited	limit	VBN
cord-017784-4r3fpmlb	38	21	by	by	IN
cord-017784-4r3fpmlb	38	22	the	the	DT
cord-017784-4r3fpmlb	38	23	lack	lack	NN
cord-017784-4r3fpmlb	38	24	of	of	IN
cord-017784-4r3fpmlb	38	25	strong	strong	JJ
cord-017784-4r3fpmlb	38	26	evidence	evidence	NN
cord-017784-4r3fpmlb	38	27	,	,	,
cord-017784-4r3fpmlb	38	28	studies	study	NNS
cord-017784-4r3fpmlb	38	29	show	show	VBP
cord-017784-4r3fpmlb	38	30	that	that	IN
cord-017784-4r3fpmlb	38	31	early	early	JJ
cord-017784-4r3fpmlb	38	32	antibiotic	antibiotic	JJ
cord-017784-4r3fpmlb	38	33	administration	administration	NN
cord-017784-4r3fpmlb	38	34	is	be	VBZ
cord-017784-4r3fpmlb	38	35	associated	associate	VBN
cord-017784-4r3fpmlb	38	36	with	with	IN
cord-017784-4r3fpmlb	38	37	improved	improved	JJ
cord-017784-4r3fpmlb	38	38	outcomes	outcome	NNS
cord-017784-4r3fpmlb	38	39	among	among	IN
cord-017784-4r3fpmlb	38	40	patients	patient	NNS
cord-017784-4r3fpmlb	38	41	hospitalized	hospitalize	VBN
cord-017784-4r3fpmlb	38	42	for	for	IN
cord-017784-4r3fpmlb	38	43	acute	acute	JJ
cord-017784-4r3fpmlb	38	44	exacerbations	exacerbation	NNS
cord-017784-4r3fpmlb	38	45	of	of	IN
cord-017784-4r3fpmlb	38	46	COPD	COPD	NNP
cord-017784-4r3fpmlb	38	47	[	[	-LRB-
cord-017784-4r3fpmlb	38	48	9	9	CD
cord-017784-4r3fpmlb	38	49	]	]	-RRB-
cord-017784-4r3fpmlb	38	50	.	.	.
cord-017784-4r3fpmlb	39	1	Furthermore	furthermore	RB
cord-017784-4r3fpmlb	39	2	inadequate	inadequate	JJ
cord-017784-4r3fpmlb	39	3	antibiotic	antibiotic	JJ
cord-017784-4r3fpmlb	39	4	therapy	therapy	NN
cord-017784-4r3fpmlb	39	5	,	,	,
cord-017784-4r3fpmlb	39	6	which	which	WDT
cord-017784-4r3fpmlb	39	7	through	through	IN
cord-017784-4r3fpmlb	39	8	incomplete	incomplete	JJ
cord-017784-4r3fpmlb	39	9	resolution	resolution	NN
cord-017784-4r3fpmlb	39	10	of	of	IN
cord-017784-4r3fpmlb	39	11	the	the	DT
cord-017784-4r3fpmlb	39	12	initial	initial	JJ
cord-017784-4r3fpmlb	39	13	exacerbation	exacerbation	NN
cord-017784-4r3fpmlb	39	14	and	and	CC
cord-017784-4r3fpmlb	39	15	persistent	persistent	JJ
cord-017784-4r3fpmlb	39	16	bacterial	bacterial	JJ
cord-017784-4r3fpmlb	39	17	infection	infection	NN
cord-017784-4r3fpmlb	39	18	,	,	,
cord-017784-4r3fpmlb	39	19	is	be	VBZ
cord-017784-4r3fpmlb	39	20	likely	likely	JJ
cord-017784-4r3fpmlb	39	21	to	to	TO
cord-017784-4r3fpmlb	39	22	influence	influence	VB
cord-017784-4r3fpmlb	39	23	the	the	DT
cord-017784-4r3fpmlb	39	24	risk	risk	NN
cord-017784-4r3fpmlb	39	25	of	of	IN
cord-017784-4r3fpmlb	39	26	relapse	relapse	NN
cord-017784-4r3fpmlb	39	27	.	.	.
cord-017784-4r3fpmlb	40	1	Exacerbations	exacerbation	NNS
cord-017784-4r3fpmlb	40	2	of	of	IN
cord-017784-4r3fpmlb	40	3	chronic	chronic	JJ
cord-017784-4r3fpmlb	40	4	obstructive	obstructive	JJ
cord-017784-4r3fpmlb	40	5	pulmonary	pulmonary	JJ
cord-017784-4r3fpmlb	40	6	disease	disease	NN
cord-017784-4r3fpmlb	40	7	(	(	-LRB-
cord-017784-4r3fpmlb	40	8	COPD	COPD	NNP
cord-017784-4r3fpmlb	40	9	)	)	-RRB-
cord-017784-4r3fpmlb	40	10	are	be	VBP
cord-017784-4r3fpmlb	40	11	defined	define	VBN
cord-017784-4r3fpmlb	40	12	as	as	IN
cord-017784-4r3fpmlb	40	13	sustained	sustain	VBN
cord-017784-4r3fpmlb	40	14	worsening	worsen	VBG
cord-017784-4r3fpmlb	40	15	of	of	IN
cord-017784-4r3fpmlb	40	16	a	a	DT
cord-017784-4r3fpmlb	40	17	patient	patient	NN
cord-017784-4r3fpmlb	40	18	's	's	POS
cord-017784-4r3fpmlb	40	19	condition	condition	NN
cord-017784-4r3fpmlb	40	20	beyond	beyond	IN
cord-017784-4r3fpmlb	40	21	normal	normal	JJ
cord-017784-4r3fpmlb	40	22	day	day	NN
cord-017784-4r3fpmlb	40	23	-	-	HYPH
cord-017784-4r3fpmlb	40	24	to	to	IN
cord-017784-4r3fpmlb	40	25	-	-	HYPH
cord-017784-4r3fpmlb	40	26	day	day	NN
cord-017784-4r3fpmlb	40	27	variations	variation	NNS
cord-017784-4r3fpmlb	40	28	that	that	WDT
cord-017784-4r3fpmlb	40	29	is	be	VBZ
cord-017784-4r3fpmlb	40	30	acute	acute	JJ
cord-017784-4r3fpmlb	40	31	in	in	IN
cord-017784-4r3fpmlb	40	32	onset	onset	NN
cord-017784-4r3fpmlb	40	33	,	,	,
cord-017784-4r3fpmlb	40	34	and	and	CC
cord-017784-4r3fpmlb	40	35	that	that	DT
cord-017784-4r3fpmlb	40	36	may	may	MD
cord-017784-4r3fpmlb	40	37	also	also	RB
cord-017784-4r3fpmlb	40	38	require	require	VB
cord-017784-4r3fpmlb	40	39	a	a	DT
cord-017784-4r3fpmlb	40	40	change	change	NN
cord-017784-4r3fpmlb	40	41	in	in	IN
cord-017784-4r3fpmlb	40	42	medication	medication	NN
cord-017784-4r3fpmlb	40	43	and/or	and/or	CC
cord-017784-4r3fpmlb	40	44	hospitalization	hospitalization	NN
cord-017784-4r3fpmlb	40	45	[	[	-LRB-
cord-017784-4r3fpmlb	40	46	10	10	CD
cord-017784-4r3fpmlb	40	47	]	]	-RRB-
cord-017784-4r3fpmlb	40	48	.	.	.
cord-017784-4r3fpmlb	41	1	An	an	DT
cord-017784-4r3fpmlb	41	2	acute	acute	JJ
cord-017784-4r3fpmlb	41	3	COPD	COPD	NNP
cord-017784-4r3fpmlb	41	4	exacerbation	exacerbation	NN
cord-017784-4r3fpmlb	41	5	can	can	MD
cord-017784-4r3fpmlb	41	6	be	be	VB
cord-017784-4r3fpmlb	41	7	viewed	view	VBN
cord-017784-4r3fpmlb	41	8	as	as	IN
cord-017784-4r3fpmlb	41	9	an	an	DT
cord-017784-4r3fpmlb	41	10	acute	acute	JJ
cord-017784-4r3fpmlb	41	11	inflammatory	inflammatory	JJ
cord-017784-4r3fpmlb	41	12	event	event	NN
cord-017784-4r3fpmlb	41	13	superimposed	superimpose	VBN
cord-017784-4r3fpmlb	41	14	on	on	IN
cord-017784-4r3fpmlb	41	15	chronic	chronic	JJ
cord-017784-4r3fpmlb	41	16	inflammation	inflammation	NN
cord-017784-4r3fpmlb	41	17	associated	associate	VBN
cord-017784-4r3fpmlb	41	18	with	with	IN
cord-017784-4r3fpmlb	41	19	COPD	COPD	NNP
cord-017784-4r3fpmlb	41	20	.	.	.
cord-017784-4r3fpmlb	42	1	Most	Most	JJS
cord-017784-4r3fpmlb	42	2	AECOPD	AECOPD	NNS
cord-017784-4r3fpmlb	42	3	may	may	MD
cord-017784-4r3fpmlb	42	4	be	be	VB
cord-017784-4r3fpmlb	42	5	due	due	JJ
cord-017784-4r3fpmlb	42	6	to	to	IN
cord-017784-4r3fpmlb	42	7	viral	viral	JJ
cord-017784-4r3fpmlb	42	8	infection	infection	NN
cord-017784-4r3fpmlb	42	9	or	or	CC
cord-017784-4r3fpmlb	42	10	bacterial	bacterial	JJ
cord-017784-4r3fpmlb	42	11	infection	infection	NN
cord-017784-4r3fpmlb	42	12	(	(	-LRB-
cord-017784-4r3fpmlb	42	13	50	50	CD
cord-017784-4r3fpmlb	42	14	%	%	NN
cord-017784-4r3fpmlb	42	15	)	)	-RRB-
cord-017784-4r3fpmlb	42	16	,	,	,
cord-017784-4r3fpmlb	42	17	but	but	CC
cord-017784-4r3fpmlb	42	18	irritants	irritant	NNS
cord-017784-4r3fpmlb	42	19	such	such	JJ
cord-017784-4r3fpmlb	42	20	as	as	IN
cord-017784-4r3fpmlb	42	21	smoke	smoke	NN
cord-017784-4r3fpmlb	42	22	or	or	CC
cord-017784-4r3fpmlb	42	23	environmental	environmental	JJ
cord-017784-4r3fpmlb	42	24	factors	factor	NNS
cord-017784-4r3fpmlb	42	25	such	such	JJ
cord-017784-4r3fpmlb	42	26	as	as	IN
cord-017784-4r3fpmlb	42	27	low	low	JJ
cord-017784-4r3fpmlb	42	28	temperature	temperature	NN
cord-017784-4r3fpmlb	42	29	and	and	CC
cord-017784-4r3fpmlb	42	30	air	air	NN
cord-017784-4r3fpmlb	42	31	pollution	pollution	NN
cord-017784-4r3fpmlb	42	32	account	account	NN
cord-017784-4r3fpmlb	42	33	for	for	IN
cord-017784-4r3fpmlb	42	34	15	15	CD
cord-017784-4r3fpmlb	42	35	-	-	SYM
cord-017784-4r3fpmlb	42	36	20	20	CD
cord-017784-4r3fpmlb	42	37	%	%	NN
cord-017784-4r3fpmlb	42	38	of	of	IN
cord-017784-4r3fpmlb	42	39	exacerbations	exacerbation	NNS
cord-017784-4r3fpmlb	42	40	[	[	-LRB-
cord-017784-4r3fpmlb	42	41	11	11	CD
cord-017784-4r3fpmlb	42	42	]	]	-RRB-
cord-017784-4r3fpmlb	42	43	.	.	.
cord-017784-4r3fpmlb	43	1	In	in	IN
cord-017784-4r3fpmlb	43	2	patients	patient	NNS
cord-017784-4r3fpmlb	43	3	with	with	IN
cord-017784-4r3fpmlb	43	4	mild	mild	JJ
cord-017784-4r3fpmlb	43	5	disease	disease	NN
cord-017784-4r3fpmlb	43	6	,	,	,
cord-017784-4r3fpmlb	43	7	Streptococcus	streptococcus	NN
cord-017784-4r3fpmlb	43	8	pneumoniae	pneumoniae	NN
cord-017784-4r3fpmlb	43	9	,	,	,
cord-017784-4r3fpmlb	43	10	Haemophilus	haemophilus	JJ
cord-017784-4r3fpmlb	43	11	influenzae	influenzae	NN
cord-017784-4r3fpmlb	43	12	,	,	,
cord-017784-4r3fpmlb	43	13	and	and	CC
cord-017784-4r3fpmlb	43	14	Moraxella	Moraxella	NNP
cord-017784-4r3fpmlb	43	15	catarrhalis	catarrhalis	NNP
cord-017784-4r3fpmlb	43	16	are	be	VBP
cord-017784-4r3fpmlb	43	17	the	the	DT
cord-017784-4r3fpmlb	43	18	predominant	predominant	JJ
cord-017784-4r3fpmlb	43	19	microorganisms	microorganism	NNS
cord-017784-4r3fpmlb	43	20	,	,	,
cord-017784-4r3fpmlb	43	21	whereas	whereas	IN
cord-017784-4r3fpmlb	43	22	in	in	IN
cord-017784-4r3fpmlb	43	23	patients	patient	NNS
cord-017784-4r3fpmlb	43	24	with	with	IN
cord-017784-4r3fpmlb	43	25	severe	severe	JJ
cord-017784-4r3fpmlb	43	26	COPD	COPD	NNP
cord-017784-4r3fpmlb	43	27	,	,	,
cord-017784-4r3fpmlb	43	28	requiring	require	VBG
cord-017784-4r3fpmlb	43	29	mechanical	mechanical	JJ
cord-017784-4r3fpmlb	43	30	ventilation	ventilation	NN
cord-017784-4r3fpmlb	43	31	,	,	,
cord-017784-4r3fpmlb	43	32	levels	level	NNS
cord-017784-4r3fpmlb	43	33	of	of	IN
cord-017784-4r3fpmlb	43	34	these	these	DT
cord-017784-4r3fpmlb	43	35	bacteria	bacteria	NNS
cord-017784-4r3fpmlb	43	36	are	be	VBP
cord-017784-4r3fpmlb	43	37	reduced	reduce	VBN
cord-017784-4r3fpmlb	43	38	and	and	CC
cord-017784-4r3fpmlb	43	39	other	other	JJ
cord-017784-4r3fpmlb	43	40	microorganism	microorganism	NN
cord-017784-4r3fpmlb	43	41	such	such	JJ
cord-017784-4r3fpmlb	43	42	as	as	IN
cord-017784-4r3fpmlb	43	43	Haemophilus	haemophilus	JJ
cord-017784-4r3fpmlb	43	44	parainfluenzae	parainfluenzae	NNS
cord-017784-4r3fpmlb	43	45	and	and	CC
cord-017784-4r3fpmlb	43	46	Pseudomonas	Pseudomonas	NNP
cord-017784-4r3fpmlb	43	47	aeruginosa	aeruginosa	NN
cord-017784-4r3fpmlb	43	48	predominate	predominate	VBP
cord-017784-4r3fpmlb	43	49	.	.	.
cord-017784-4r3fpmlb	44	1	It	-PRON-	PRP
cord-017784-4r3fpmlb	44	2	has	have	VBZ
cord-017784-4r3fpmlb	44	3	also	also	RB
cord-017784-4r3fpmlb	44	4	been	be	VBN
cord-017784-4r3fpmlb	44	5	observed	observe	VBN
cord-017784-4r3fpmlb	44	6	that	that	IN
cord-017784-4r3fpmlb	44	7	the	the	DT
cord-017784-4r3fpmlb	44	8	severity	severity	NN
cord-017784-4r3fpmlb	44	9	of	of	IN
cord-017784-4r3fpmlb	44	10	lung	lung	NN
cord-017784-4r3fpmlb	44	11	function	function	NN
cord-017784-4r3fpmlb	44	12	,	,	,
cord-017784-4r3fpmlb	44	13	measured	measure	VBN
cord-017784-4r3fpmlb	44	14	by	by	IN
cord-017784-4r3fpmlb	44	15	FEV1	FEV1	NNP
cord-017784-4r3fpmlb	44	16	,	,	,
cord-017784-4r3fpmlb	44	17	has	have	VBZ
cord-017784-4r3fpmlb	44	18	an	an	DT
cord-017784-4r3fpmlb	44	19	impact	impact	NN
cord-017784-4r3fpmlb	44	20	on	on	IN
cord-017784-4r3fpmlb	44	21	the	the	DT
cord-017784-4r3fpmlb	44	22	microbiology	microbiology	NN
cord-017784-4r3fpmlb	44	23	of	of	IN
cord-017784-4r3fpmlb	44	24	exacerbation	exacerbation	NN
cord-017784-4r3fpmlb	44	25	[	[	-LRB-
cord-017784-4r3fpmlb	44	26	12	12	CD
cord-017784-4r3fpmlb	44	27	]	]	-RRB-
cord-017784-4r3fpmlb	44	28	.	.	.
cord-017784-4r3fpmlb	45	1	Patients	patient	NNS
cord-017784-4r3fpmlb	45	2	with	with	IN
cord-017784-4r3fpmlb	45	3	increased	increase	VBN
cord-017784-4r3fpmlb	45	4	airway	airway	JJ
cord-017784-4r3fpmlb	45	5	obstruction	obstruction	NN
cord-017784-4r3fpmlb	45	6	and	and	CC
cord-017784-4r3fpmlb	45	7	frequent	frequent	JJ
cord-017784-4r3fpmlb	45	8	exacerbations	exacerbation	NNS
cord-017784-4r3fpmlb	45	9	,	,	,
cord-017784-4r3fpmlb	45	10	the	the	DT
cord-017784-4r3fpmlb	45	11	microbiology	microbiology	NN
cord-017784-4r3fpmlb	45	12	of	of	IN
cord-017784-4r3fpmlb	45	13	the	the	DT
cord-017784-4r3fpmlb	45	14	exacerbations	exacerbation	NNS
cord-017784-4r3fpmlb	45	15	is	be	VBZ
cord-017784-4r3fpmlb	45	16	often	often	RB
cord-017784-4r3fpmlb	45	17	more	more	RBR
cord-017784-4r3fpmlb	45	18	complex	complex	JJ
cord-017784-4r3fpmlb	45	19	,	,	,
cord-017784-4r3fpmlb	45	20	with	with	IN
cord-017784-4r3fpmlb	45	21	a	a	DT
cord-017784-4r3fpmlb	45	22	predominance	predominance	NN
cord-017784-4r3fpmlb	45	23	of	of	IN
cord-017784-4r3fpmlb	45	24	Enterobacteriaceae	Enterobacteriaceae	NNP
cord-017784-4r3fpmlb	45	25	and	and	CC
cord-017784-4r3fpmlb	45	26	Pseudomonas	Pseudomonas	NNP
cord-017784-4r3fpmlb	45	27	aeruginosa	aeruginosa	NN
cord-017784-4r3fpmlb	45	28	.	.	.
cord-017784-4r3fpmlb	46	1	The	the	DT
cord-017784-4r3fpmlb	46	2	role	role	NN
cord-017784-4r3fpmlb	46	3	of	of	IN
cord-017784-4r3fpmlb	46	4	atypical	atypical	JJ
cord-017784-4r3fpmlb	46	5	microorganisms	microorganism	NNS
cord-017784-4r3fpmlb	46	6	is	be	VBZ
cord-017784-4r3fpmlb	46	7	the	the	DT
cord-017784-4r3fpmlb	46	8	subject	subject	NN
cord-017784-4r3fpmlb	46	9	of	of	IN
cord-017784-4r3fpmlb	46	10	debate	debate	NN
cord-017784-4r3fpmlb	46	11	.	.	.
cord-017784-4r3fpmlb	47	1	According	accord	VBG
cord-017784-4r3fpmlb	47	2	to	to	IN
cord-017784-4r3fpmlb	47	3	some	some	DT
cord-017784-4r3fpmlb	47	4	authors	author	NNS
cord-017784-4r3fpmlb	47	5	,	,	,
cord-017784-4r3fpmlb	47	6	there	there	EX
cord-017784-4r3fpmlb	47	7	is	be	VBZ
cord-017784-4r3fpmlb	47	8	no	no	DT
cord-017784-4r3fpmlb	47	9	association	association	NN
cord-017784-4r3fpmlb	47	10	between	between	IN
cord-017784-4r3fpmlb	47	11	the	the	DT
cord-017784-4r3fpmlb	47	12	presence	presence	NN
cord-017784-4r3fpmlb	47	13	of	of	IN
cord-017784-4r3fpmlb	47	14	organisms	organism	NNS
cord-017784-4r3fpmlb	47	15	such	such	JJ
cord-017784-4r3fpmlb	47	16	as	as	IN
cord-017784-4r3fpmlb	47	17	Chlamydia	Chlamydia	NNP
cord-017784-4r3fpmlb	47	18	pneumoniae	pneumoniae	NN
cord-017784-4r3fpmlb	47	19	,	,	,
cord-017784-4r3fpmlb	47	20	Legionella	Legionella	NNP
cord-017784-4r3fpmlb	47	21	spp	spp	NNS
cord-017784-4r3fpmlb	47	22	.	.	.
cord-017784-4r3fpmlb	48	1	,	,	,
cord-017784-4r3fpmlb	48	2	Mycoplasma	mycoplasma	NN
cord-017784-4r3fpmlb	48	3	pneumoniae	pneumoniae	NN
cord-017784-4r3fpmlb	48	4	,	,	,
cord-017784-4r3fpmlb	48	5	and	and	CC
cord-017784-4r3fpmlb	48	6	AECOPD	AECOPD	NNP
cord-017784-4r3fpmlb	48	7	[	[	-LRB-
cord-017784-4r3fpmlb	48	8	13	13	CD
cord-017784-4r3fpmlb	48	9	]	]	-RRB-
cord-017784-4r3fpmlb	48	10	.	.	.
cord-017784-4r3fpmlb	49	1	However	however	RB
cord-017784-4r3fpmlb	49	2	,	,	,
cord-017784-4r3fpmlb	49	3	in	in	IN
cord-017784-4r3fpmlb	49	4	AECB	AECB	NNP
cord-017784-4r3fpmlb	49	5	,	,	,
cord-017784-4r3fpmlb	49	6	several	several	JJ
cord-017784-4r3fpmlb	49	7	older	old	JJR
cord-017784-4r3fpmlb	49	8	studies	study	NNS
cord-017784-4r3fpmlb	49	9	and	and	CC
cord-017784-4r3fpmlb	49	10	a	a	DT
cord-017784-4r3fpmlb	49	11	few	few	JJ
cord-017784-4r3fpmlb	49	12	recent	recent	JJ
cord-017784-4r3fpmlb	49	13	studies	study	NNS
cord-017784-4r3fpmlb	49	14	have	have	VBP
cord-017784-4r3fpmlb	49	15	implicated	implicate	VBN
cord-017784-4r3fpmlb	49	16	atypical	atypical	JJ
cord-017784-4r3fpmlb	49	17	bacteria	bacteria	NNS
cord-017784-4r3fpmlb	49	18	in	in	IN
cord-017784-4r3fpmlb	49	19	only	only	RB
cord-017784-4r3fpmlb	49	20	5	5	CD
cord-017784-4r3fpmlb	49	21	-	-	SYM
cord-017784-4r3fpmlb	49	22	10	10	CD
cord-017784-4r3fpmlb	49	23	%	%	NN
cord-017784-4r3fpmlb	49	24	of	of	IN
cord-017784-4r3fpmlb	49	25	episodes	episode	NNS
cord-017784-4r3fpmlb	49	26	[	[	-LRB-
cord-017784-4r3fpmlb	49	27	14	14	CD
cord-017784-4r3fpmlb	49	28	]	]	-RRB-
cord-017784-4r3fpmlb	49	29	.	.	.
cord-017784-4r3fpmlb	50	1	Although	although	IN
cord-017784-4r3fpmlb	50	2	it	-PRON-	PRP
cord-017784-4r3fpmlb	50	3	is	be	VBZ
cord-017784-4r3fpmlb	50	4	difficult	difficult	JJ
cord-017784-4r3fpmlb	50	5	to	to	TO
cord-017784-4r3fpmlb	50	6	define	define	VB
cord-017784-4r3fpmlb	50	7	precisely	precisely	RB
cord-017784-4r3fpmlb	50	8	the	the	DT
cord-017784-4r3fpmlb	50	9	proportion	proportion	NN
cord-017784-4r3fpmlb	50	10	of	of	IN
cord-017784-4r3fpmlb	50	11	exacerbations	exacerbation	NNS
cord-017784-4r3fpmlb	50	12	caused	cause	VBN
cord-017784-4r3fpmlb	50	13	by	by	IN
cord-017784-4r3fpmlb	50	14	viruses	virus	NNS
cord-017784-4r3fpmlb	50	15	,	,	,
cord-017784-4r3fpmlb	50	16	they	-PRON-	PRP
cord-017784-4r3fpmlb	50	17	are	be	VBP
cord-017784-4r3fpmlb	50	18	often	often	RB
cord-017784-4r3fpmlb	50	19	implicated	implicate	VBN
cord-017784-4r3fpmlb	50	20	in	in	IN
cord-017784-4r3fpmlb	50	21	AECOPD	AECOPD	NNP
cord-017784-4r3fpmlb	50	22	(	(	-LRB-
cord-017784-4r3fpmlb	50	23	up	up	IN
cord-017784-4r3fpmlb	50	24	to	to	TO
cord-017784-4r3fpmlb	50	25	30	30	CD
cord-017784-4r3fpmlb	50	26	%	%	NN
cord-017784-4r3fpmlb	50	27	of	of	IN
cord-017784-4r3fpmlb	50	28	cases	case	NNS
cord-017784-4r3fpmlb	50	29	)	)	-RRB-
cord-017784-4r3fpmlb	51	1	[	[	-LRB-
cord-017784-4r3fpmlb	51	2	15	15	CD
cord-017784-4r3fpmlb	51	3	]	]	-RRB-
cord-017784-4r3fpmlb	51	4	.	.	.
cord-017784-4r3fpmlb	52	1	The	the	DT
cord-017784-4r3fpmlb	52	2	most	most	RBS
cord-017784-4r3fpmlb	52	3	common	common	JJ
cord-017784-4r3fpmlb	52	4	viruses	virus	NNS
cord-017784-4r3fpmlb	52	5	associated	associate	VBN
cord-017784-4r3fpmlb	52	6	with	with	IN
cord-017784-4r3fpmlb	52	7	exacerbations	exacerbation	NNS
cord-017784-4r3fpmlb	52	8	of	of	IN
cord-017784-4r3fpmlb	52	9	COPD	COPD	NNP
cord-017784-4r3fpmlb	52	10	are	be	VBP
cord-017784-4r3fpmlb	52	11	rhinoviruses	rhinovirus	NNS
cord-017784-4r3fpmlb	52	12	,	,	,
cord-017784-4r3fpmlb	52	13	but	but	CC
cord-017784-4r3fpmlb	52	14	in	in	IN
cord-017784-4r3fpmlb	52	15	more	more	RBR
cord-017784-4r3fpmlb	52	16	severe	severe	JJ
cord-017784-4r3fpmlb	52	17	exacerbations	exacerbation	NNS
cord-017784-4r3fpmlb	52	18	requiring	require	VBG
cord-017784-4r3fpmlb	52	19	hospitalization	hospitalization	NN
cord-017784-4r3fpmlb	52	20	,	,	,
cord-017784-4r3fpmlb	52	21	influenza	influenza	NN
cord-017784-4r3fpmlb	52	22	virus	virus	NN
cord-017784-4r3fpmlb	52	23	is	be	VBZ
cord-017784-4r3fpmlb	52	24	more	more	RBR
cord-017784-4r3fpmlb	52	25	common	common	JJ
cord-017784-4r3fpmlb	52	26	.	.	.
cord-017784-4r3fpmlb	53	1	Viral	viral	JJ
cord-017784-4r3fpmlb	53	2	infection	infection	NN
cord-017784-4r3fpmlb	53	3	may	may	MD
cord-017784-4r3fpmlb	53	4	,	,	,
cord-017784-4r3fpmlb	53	5	also	also	RB
cord-017784-4r3fpmlb	53	6	,	,	,
cord-017784-4r3fpmlb	53	7	facilitate	facilitate	VB
cord-017784-4r3fpmlb	53	8	subsequent	subsequent	JJ
cord-017784-4r3fpmlb	53	9	bacterial	bacterial	JJ
cord-017784-4r3fpmlb	53	10	infection	infection	NN
cord-017784-4r3fpmlb	53	11	or	or	CC
cord-017784-4r3fpmlb	53	12	increase	increase	VB
cord-017784-4r3fpmlb	53	13	the	the	DT
cord-017784-4r3fpmlb	53	14	number	number	NN
cord-017784-4r3fpmlb	53	15	of	of	IN
cord-017784-4r3fpmlb	53	16	bacteria	bacteria	NNS
cord-017784-4r3fpmlb	53	17	already	already	RB
cord-017784-4r3fpmlb	53	18	present	present	JJ
cord-017784-4r3fpmlb	53	19	in	in	IN
cord-017784-4r3fpmlb	53	20	the	the	DT
cord-017784-4r3fpmlb	53	21	lower	low	JJR
cord-017784-4r3fpmlb	53	22	airways	airway	NNS
cord-017784-4r3fpmlb	53	23	.	.	.
cord-017784-4r3fpmlb	54	1	The	the	DT
cord-017784-4r3fpmlb	54	2	use	use	NN
cord-017784-4r3fpmlb	54	3	of	of	IN
cord-017784-4r3fpmlb	54	4	antibiotics	antibiotic	NNS
cord-017784-4r3fpmlb	54	5	in	in	IN
cord-017784-4r3fpmlb	54	6	exacerbations	exacerbation	NNS
cord-017784-4r3fpmlb	54	7	COPD	COPD	NNP
cord-017784-4r3fpmlb	54	8	remains	remain	VBZ
cord-017784-4r3fpmlb	54	9	controversial	controversial	JJ
cord-017784-4r3fpmlb	54	10	;	;	:
cord-017784-4r3fpmlb	54	11	therefore	therefore	RB
cord-017784-4r3fpmlb	54	12	,	,	,
cord-017784-4r3fpmlb	54	13	in	in	IN
cord-017784-4r3fpmlb	54	14	the	the	DT
cord-017784-4r3fpmlb	54	15	era	era	NN
cord-017784-4r3fpmlb	54	16	of	of	IN
cord-017784-4r3fpmlb	54	17	antibiotic	antibiotic	JJ
cord-017784-4r3fpmlb	54	18	resistance	resistance	NN
cord-017784-4r3fpmlb	54	19	,	,	,
cord-017784-4r3fpmlb	54	20	the	the	DT
cord-017784-4r3fpmlb	54	21	identification	identification	NN
cord-017784-4r3fpmlb	54	22	of	of	IN
cord-017784-4r3fpmlb	54	23	clinical	clinical	JJ
cord-017784-4r3fpmlb	54	24	characteristics	characteristic	NNS
cord-017784-4r3fpmlb	54	25	that	that	WDT
cord-017784-4r3fpmlb	54	26	identify	identify	VBP
cord-017784-4r3fpmlb	54	27	patients	patient	NNS
cord-017784-4r3fpmlb	54	28	with	with	IN
cord-017784-4r3fpmlb	54	29	AECOPD	AECOPD	NNP
cord-017784-4r3fpmlb	54	30	that	that	WDT
cord-017784-4r3fpmlb	54	31	can	can	MD
cord-017784-4r3fpmlb	54	32	be	be	VB
cord-017784-4r3fpmlb	54	33	safely	safely	RB
cord-017784-4r3fpmlb	54	34	treated	treat	VBN
cord-017784-4r3fpmlb	54	35	without	without	IN
cord-017784-4r3fpmlb	54	36	antibiotics	antibiotic	NNS
cord-017784-4r3fpmlb	54	37	is	be	VBZ
cord-017784-4r3fpmlb	54	38	extremely	extremely	RB
cord-017784-4r3fpmlb	54	39	important	important	JJ
cord-017784-4r3fpmlb	54	40	.	.	.
cord-017784-4r3fpmlb	55	1	There	there	EX
cord-017784-4r3fpmlb	55	2	is	be	VBZ
cord-017784-4r3fpmlb	55	3	evidence	evidence	NN
cord-017784-4r3fpmlb	55	4	supporting	support	VBG
cord-017784-4r3fpmlb	55	5	the	the	DT
cord-017784-4r3fpmlb	55	6	use	use	NN
cord-017784-4r3fpmlb	55	7	antibiotics	antibiotic	NNS
cord-017784-4r3fpmlb	55	8	in	in	IN
cord-017784-4r3fpmlb	55	9	exacerbations	exacerbation	NNS
cord-017784-4r3fpmlb	55	10	when	when	WRB
cord-017784-4r3fpmlb	55	11	patients	patient	NNS
cord-017784-4r3fpmlb	55	12	have	have	VBP
cord-017784-4r3fpmlb	55	13	clinical	clinical	JJ
cord-017784-4r3fpmlb	55	14	signs	sign	NNS
cord-017784-4r3fpmlb	55	15	of	of	IN
cord-017784-4r3fpmlb	55	16	a	a	DT
cord-017784-4r3fpmlb	55	17	bacterial	bacterial	JJ
cord-017784-4r3fpmlb	55	18	infection	infection	NN
cord-017784-4r3fpmlb	55	19	,	,	,
cord-017784-4r3fpmlb	55	20	e.g.	e.g.	RB
cord-017784-4r3fpmlb	55	21	,	,	,
cord-017784-4r3fpmlb	55	22	increased	increase	VBN
cord-017784-4r3fpmlb	55	23	sputum	sputum	NN
cord-017784-4r3fpmlb	55	24	purulence	purulence	NN
cord-017784-4r3fpmlb	55	25	,	,	,
cord-017784-4r3fpmlb	55	26	especially	especially	RB
cord-017784-4r3fpmlb	55	27	when	when	WRB
cord-017784-4r3fpmlb	55	28	there	there	EX
cord-017784-4r3fpmlb	55	29	are	be	VBP
cord-017784-4r3fpmlb	55	30	changes	change	NNS
cord-017784-4r3fpmlb	55	31	in	in	IN
cord-017784-4r3fpmlb	55	32	the	the	DT
cord-017784-4r3fpmlb	55	33	color	color	NN
cord-017784-4r3fpmlb	55	34	of	of	IN
cord-017784-4r3fpmlb	55	35	sputum	sputum	NN
cord-017784-4r3fpmlb	55	36	[	[	-LRB-
cord-017784-4r3fpmlb	55	37	16	16	CD
cord-017784-4r3fpmlb	55	38	]	]	-RRB-
cord-017784-4r3fpmlb	55	39	.	.	.
cord-017784-4r3fpmlb	56	1	Antibiotics	antibiotic	NNS
cord-017784-4r3fpmlb	56	2	are	be	VBP
cord-017784-4r3fpmlb	56	3	also	also	RB
cord-017784-4r3fpmlb	56	4	recommended	recommend	VBN
cord-017784-4r3fpmlb	56	5	for	for	IN
cord-017784-4r3fpmlb	56	6	patients	patient	NNS
cord-017784-4r3fpmlb	56	7	with	with	IN
cord-017784-4r3fpmlb	56	8	exacerbations	exacerbation	NNS
cord-017784-4r3fpmlb	56	9	requiring	require	VBG
cord-017784-4r3fpmlb	56	10	mechanical	mechanical	JJ
cord-017784-4r3fpmlb	56	11	ventilation	ventilation	NN
cord-017784-4r3fpmlb	56	12	,	,	,
cord-017784-4r3fpmlb	56	13	as	as	IN
cord-017784-4r3fpmlb	56	14	this	this	DT
cord-017784-4r3fpmlb	56	15	has	have	VBZ
cord-017784-4r3fpmlb	56	16	been	be	VBN
cord-017784-4r3fpmlb	56	17	shown	show	VBN
cord-017784-4r3fpmlb	56	18	significantly	significantly	RB
cord-017784-4r3fpmlb	56	19	to	to	TO
cord-017784-4r3fpmlb	56	20	reduce	reduce	VB
cord-017784-4r3fpmlb	56	21	mortality	mortality	NN
cord-017784-4r3fpmlb	56	22	and	and	CC
cord-017784-4r3fpmlb	56	23	the	the	DT
cord-017784-4r3fpmlb	56	24	risk	risk	NN
cord-017784-4r3fpmlb	56	25	of	of	IN
cord-017784-4r3fpmlb	56	26	secondary	secondary	JJ
cord-017784-4r3fpmlb	56	27	pneumonia	pneumonia	NN
cord-017784-4r3fpmlb	56	28	.	.	.
cord-017784-4r3fpmlb	57	1	In	in	IN
cord-017784-4r3fpmlb	57	2	summary	summary	NN
cord-017784-4r3fpmlb	57	3	,	,	,
cord-017784-4r3fpmlb	57	4	antibiotics	antibiotic	NNS
cord-017784-4r3fpmlb	57	5	should	should	MD
cord-017784-4r3fpmlb	57	6	be	be	VB
cord-017784-4r3fpmlb	57	7	given	give	VBN
cord-017784-4r3fpmlb	57	8	to	to	IN
cord-017784-4r3fpmlb	57	9	patients	patient	NNS
cord-017784-4r3fpmlb	57	10	with	with	IN
cord-017784-4r3fpmlb	57	11	exacerbations	exacerbation	NNS
cord-017784-4r3fpmlb	57	12	of	of	IN
cord-017784-4r3fpmlb	57	13	COPD	COPD	NNP
cord-017784-4r3fpmlb	57	14	who	who	WP
cord-017784-4r3fpmlb	57	15	have	have	VBP
cord-017784-4r3fpmlb	57	16	three	three	CD
cord-017784-4r3fpmlb	57	17	cardinal	cardinal	JJ
cord-017784-4r3fpmlb	57	18	symptoms	symptom	NNS
cord-017784-4r3fpmlb	57	19	:	:	:
cord-017784-4r3fpmlb	57	20	increase	increase	VB
cord-017784-4r3fpmlb	57	21	in	in	IN
cord-017784-4r3fpmlb	57	22	dyspnea	dyspnea	NN
cord-017784-4r3fpmlb	57	23	,	,	,
cord-017784-4r3fpmlb	57	24	sputum	sputum	NN
cord-017784-4r3fpmlb	57	25	volume	volume	NN
cord-017784-4r3fpmlb	57	26	,	,	,
cord-017784-4r3fpmlb	57	27	and	and	CC
cord-017784-4r3fpmlb	57	28	sputum	sputum	NN
cord-017784-4r3fpmlb	57	29	purulence	purulence	NN
cord-017784-4r3fpmlb	57	30	;	;	:
cord-017784-4r3fpmlb	57	31	have	have	VB
cord-017784-4r3fpmlb	57	32	two	two	CD
cord-017784-4r3fpmlb	57	33	of	of	IN
cord-017784-4r3fpmlb	57	34	the	the	DT
cord-017784-4r3fpmlb	57	35	cardinal	cardinal	JJ
cord-017784-4r3fpmlb	57	36	symptoms	symptom	NNS
cord-017784-4r3fpmlb	57	37	if	if	IN
cord-017784-4r3fpmlb	57	38	increased	increase	VBN
cord-017784-4r3fpmlb	57	39	purulence	purulence	NN
cord-017784-4r3fpmlb	57	40	of	of	IN
cord-017784-4r3fpmlb	57	41	sputum	sputum	NN
cord-017784-4r3fpmlb	57	42	is	be	VBZ
cord-017784-4r3fpmlb	57	43	one	one	CD
cord-017784-4r3fpmlb	57	44	of	of	IN
cord-017784-4r3fpmlb	57	45	the	the	DT
cord-017784-4r3fpmlb	57	46	two	two	CD
cord-017784-4r3fpmlb	57	47	symptoms	symptom	NNS
cord-017784-4r3fpmlb	57	48	;	;	:
cord-017784-4r3fpmlb	57	49	or	or	CC
cord-017784-4r3fpmlb	57	50	require	require	VB
cord-017784-4r3fpmlb	57	51	mechanical	mechanical	JJ
cord-017784-4r3fpmlb	57	52	ventilation	ventilation	NN
cord-017784-4r3fpmlb	57	53	(	(	-LRB-
cord-017784-4r3fpmlb	57	54	invasive	invasive	JJ
cord-017784-4r3fpmlb	57	55	or	or	CC
cord-017784-4r3fpmlb	57	56	non	non	JJ
cord-017784-4r3fpmlb	57	57	-	-	JJ
cord-017784-4r3fpmlb	57	58	invasive	invasive	JJ
cord-017784-4r3fpmlb	57	59	)	)	-RRB-
cord-017784-4r3fpmlb	57	60	[	[	-LRB-
cord-017784-4r3fpmlb	57	61	10	10	CD
cord-017784-4r3fpmlb	57	62	]	]	-RRB-
cord-017784-4r3fpmlb	57	63	.	.	.
cord-017784-4r3fpmlb	58	1	(	(	-LRB-
cord-017784-4r3fpmlb	58	2	Table	table	NN
cord-017784-4r3fpmlb	58	3	5	5	CD
cord-017784-4r3fpmlb	58	4	.	.	.
cord-017784-4r3fpmlb	58	5	 	 	_SP
cord-017784-4r3fpmlb	59	1	After	after	IN
cord-017784-4r3fpmlb	59	2	the	the	DT
cord-017784-4r3fpmlb	59	3	decision	decision	NN
cord-017784-4r3fpmlb	59	4	to	to	TO
cord-017784-4r3fpmlb	59	5	initiate	initiate	VB
cord-017784-4r3fpmlb	59	6	empirical	empirical	JJ
cord-017784-4r3fpmlb	59	7	antibiotic	antibiotic	JJ
cord-017784-4r3fpmlb	59	8	therapy	therapy	NN
cord-017784-4r3fpmlb	59	9	,	,	,
cord-017784-4r3fpmlb	59	10	the	the	DT
cord-017784-4r3fpmlb	59	11	choice	choice	NN
cord-017784-4r3fpmlb	59	12	of	of	IN
cord-017784-4r3fpmlb	59	13	empirical	empirical	JJ
cord-017784-4r3fpmlb	59	14	antibiotic	antibiotic	JJ
cord-017784-4r3fpmlb	59	15	regimen	regimen	NN
cord-017784-4r3fpmlb	59	16	most	most	RBS
cord-017784-4r3fpmlb	59	17	appropriate	appropriate	JJ
cord-017784-4r3fpmlb	59	18	for	for	IN
cord-017784-4r3fpmlb	59	19	treating	treat	VBG
cord-017784-4r3fpmlb	59	20	an	an	DT
cord-017784-4r3fpmlb	59	21	episode	episode	NN
cord-017784-4r3fpmlb	59	22	of	of	IN
cord-017784-4r3fpmlb	59	23	AECOPD	AECOPD	NNP
cord-017784-4r3fpmlb	59	24	should	should	MD
cord-017784-4r3fpmlb	59	25	be	be	VB
cord-017784-4r3fpmlb	59	26	based	base	VBN
cord-017784-4r3fpmlb	59	27	on	on	IN
cord-017784-4r3fpmlb	59	28	the	the	DT
cord-017784-4r3fpmlb	59	29	following	follow	VBG
cord-017784-4r3fpmlb	59	30	:	:	:
cord-017784-4r3fpmlb	59	31	1	1	CD
cord-017784-4r3fpmlb	59	32	.	.	.
cord-017784-4r3fpmlb	60	1	The	the	DT
cord-017784-4r3fpmlb	60	2	severity	severity	NN
cord-017784-4r3fpmlb	60	3	of	of	IN
cord-017784-4r3fpmlb	60	4	COPD	COPD	NNP
cord-017784-4r3fpmlb	60	5	,	,	,
cord-017784-4r3fpmlb	60	6	established	establish	VBN
cord-017784-4r3fpmlb	60	7	by	by	IN
cord-017784-4r3fpmlb	60	8	FEV1	FEV1	NNP
cord-017784-4r3fpmlb	60	9	and	and	CC
cord-017784-4r3fpmlb	60	10	the	the	DT
cord-017784-4r3fpmlb	60	11	history	history	NN
cord-017784-4r3fpmlb	60	12	of	of	IN
cord-017784-4r3fpmlb	60	13	more	more	JJR
cord-017784-4r3fpmlb	60	14	than	than	IN
cord-017784-4r3fpmlb	60	15	three	three	CD
cord-017784-4r3fpmlb	60	16	exacerbations	exacerbation	NNS
cord-017784-4r3fpmlb	60	17	in	in	IN
cord-017784-4r3fpmlb	60	18	the	the	DT
cord-017784-4r3fpmlb	60	19	previous	previous	JJ
cord-017784-4r3fpmlb	60	20	12	12	CD
cord-017784-4r3fpmlb	60	21	months	month	NNS
cord-017784-4r3fpmlb	60	22	.	.	.
cord-017784-4r3fpmlb	61	1	2	2	LS
cord-017784-4r3fpmlb	61	2	.	.	.
cord-017784-4r3fpmlb	62	1	The	the	DT
cord-017784-4r3fpmlb	62	2	patients	patient	NNS
cord-017784-4r3fpmlb	62	3	age	age	NN
cord-017784-4r3fpmlb	62	4	(	(	-LRB-
cord-017784-4r3fpmlb	62	5	≥	≥	CD
cord-017784-4r3fpmlb	62	6	or	or	CC
cord-017784-4r3fpmlb	62	7	<	<	XX
cord-017784-4r3fpmlb	62	8	65	65	CD
cord-017784-4r3fpmlb	62	9	years	year	NNS
cord-017784-4r3fpmlb	62	10	)	)	-RRB-
cord-017784-4r3fpmlb	62	11	.	.	.
cord-017784-4r3fpmlb	63	1	3	3	LS
cord-017784-4r3fpmlb	63	2	.	.	.
cord-017784-4r3fpmlb	64	1	Significant	significant	JJ
cord-017784-4r3fpmlb	64	2	comorbidity	comorbidity	NN
cord-017784-4r3fpmlb	64	3	(	(	-LRB-
cord-017784-4r3fpmlb	64	4	diabetes	diabetes	NN
cord-017784-4r3fpmlb	64	5	mellitus	mellitus	NN
cord-017784-4r3fpmlb	64	6	,	,	,
cord-017784-4r3fpmlb	64	7	liver	liver	NN
cord-017784-4r3fpmlb	64	8	cirrhosis	cirrhosis	NN
cord-017784-4r3fpmlb	64	9	,	,	,
cord-017784-4r3fpmlb	64	10	chronic	chronic	JJ
cord-017784-4r3fpmlb	64	11	renal	renal	JJ
cord-017784-4r3fpmlb	64	12	failure	failure	NN
cord-017784-4r3fpmlb	64	13	,	,	,
cord-017784-4r3fpmlb	64	14	or	or	CC
cord-017784-4r3fpmlb	64	15	heart	heart	NN
cord-017784-4r3fpmlb	64	16	disease	disease	NN
cord-017784-4r3fpmlb	64	17	)	)	-RRB-
cord-017784-4r3fpmlb	64	18	.	.	.
cord-017784-4r3fpmlb	65	1	4	4	LS
cord-017784-4r3fpmlb	65	2	.	.	.
cord-017784-4r3fpmlb	66	1	The	the	DT
cord-017784-4r3fpmlb	66	2	risk	risk	NN
cord-017784-4r3fpmlb	66	3	of	of	IN
cord-017784-4r3fpmlb	66	4	infection	infection	NN
cord-017784-4r3fpmlb	66	5	due	due	JJ
cord-017784-4r3fpmlb	66	6	to	to	IN
cord-017784-4r3fpmlb	66	7	P.	P.	NNP
cord-017784-4r3fpmlb	66	8	aeruginosa	aeruginosa	NNP
cord-017784-4r3fpmlb	66	9	,	,	,
cord-017784-4r3fpmlb	66	10	which	which	WDT
cord-017784-4r3fpmlb	66	11	must	must	MD
cord-017784-4r3fpmlb	66	12	be	be	VB
cord-017784-4r3fpmlb	66	13	considered	consider	VBN
cord-017784-4r3fpmlb	66	14	in	in	IN
cord-017784-4r3fpmlb	66	15	the	the	DT
cord-017784-4r3fpmlb	66	16	presence	presence	NN
cord-017784-4r3fpmlb	66	17	of	of	IN
cord-017784-4r3fpmlb	66	18	two	two	CD
cord-017784-4r3fpmlb	66	19	of	of	IN
cord-017784-4r3fpmlb	66	20	the	the	DT
cord-017784-4r3fpmlb	66	21	following	follow	VBG
cord-017784-4r3fpmlb	66	22	risk	risk	NN
cord-017784-4r3fpmlb	66	23	factors	factor	NNS
cord-017784-4r3fpmlb	66	24	:	:	:
cord-017784-4r3fpmlb	66	25	recent	recent	JJ
cord-017784-4r3fpmlb	66	26	hospitalization	hospitalization	NN
cord-017784-4r3fpmlb	66	27	,	,	,
cord-017784-4r3fpmlb	66	28	frequent	frequent	JJ
cord-017784-4r3fpmlb	66	29	(	(	-LRB-
cord-017784-4r3fpmlb	66	30	>	>	NFP
cord-017784-4r3fpmlb	66	31	4	4	CD
cord-017784-4r3fpmlb	66	32	times	time	NNS
cord-017784-4r3fpmlb	66	33	/	/	SYM
cord-017784-4r3fpmlb	66	34	year	year	NN
cord-017784-4r3fpmlb	66	35	)	)	-RRB-
cord-017784-4r3fpmlb	66	36	or	or	CC
cord-017784-4r3fpmlb	66	37	recent	recent	JJ
cord-017784-4r3fpmlb	66	38	(	(	-LRB-
cord-017784-4r3fpmlb	66	39	within	within	IN
cord-017784-4r3fpmlb	66	40	the	the	DT
cord-017784-4r3fpmlb	66	41	previous	previous	JJ
cord-017784-4r3fpmlb	66	42	3	3	CD
cord-017784-4r3fpmlb	66	43	months	month	NNS
cord-017784-4r3fpmlb	66	44	)	)	-RRB-
cord-017784-4r3fpmlb	66	45	administration	administration	NN
cord-017784-4r3fpmlb	66	46	of	of	IN
cord-017784-4r3fpmlb	66	47	antibiotics	antibiotic	NNS
cord-017784-4r3fpmlb	66	48	,	,	,
cord-017784-4r3fpmlb	66	49	severe	severe	JJ
cord-017784-4r3fpmlb	66	50	disease	disease	NN
cord-017784-4r3fpmlb	66	51	(	(	-LRB-
cord-017784-4r3fpmlb	66	52	FEV1	FEV1	NNP
cord-017784-4r3fpmlb	66	53	<	<	XX
cord-017784-4r3fpmlb	66	54	30	30	CD
cord-017784-4r3fpmlb	66	55	%	%	NN
cord-017784-4r3fpmlb	66	56	)	)	-RRB-
cord-017784-4r3fpmlb	66	57	,	,	,
cord-017784-4r3fpmlb	66	58	or	or	CC
cord-017784-4r3fpmlb	66	59	the	the	DT
cord-017784-4r3fpmlb	66	60	use	use	NN
cord-017784-4r3fpmlb	66	61	of	of	IN
cord-017784-4r3fpmlb	66	62	oral	oral	JJ
cord-017784-4r3fpmlb	66	63	corticosteroids	corticosteroid	NNS
cord-017784-4r3fpmlb	66	64	(	(	-LRB-
cord-017784-4r3fpmlb	66	65	>	>	NFP
cord-017784-4r3fpmlb	66	66	10	10	CD
cord-017784-4r3fpmlb	66	67	mg	mg	NN
cord-017784-4r3fpmlb	66	68	of	of	IN
cord-017784-4r3fpmlb	66	69	prednisone	prednisone	NNP
cord-017784-4r3fpmlb	66	70	daily	daily	RB
cord-017784-4r3fpmlb	66	71	in	in	IN
cord-017784-4r3fpmlb	66	72	the	the	DT
cord-017784-4r3fpmlb	66	73	previous	previous	JJ
cord-017784-4r3fpmlb	66	74	2	2	CD
cord-017784-4r3fpmlb	66	75	weeks	week	NNS
cord-017784-4r3fpmlb	66	76	)	)	-RRB-
cord-017784-4r3fpmlb	66	77	.	.	.
cord-017784-4r3fpmlb	67	1	Between	between	IN
cord-017784-4r3fpmlb	67	2	10	10	CD
cord-017784-4r3fpmlb	67	3	%	%	NN
cord-017784-4r3fpmlb	67	4	and	and	CC
cord-017784-4r3fpmlb	67	5	20	20	CD
cord-017784-4r3fpmlb	67	6	%	%	NN
cord-017784-4r3fpmlb	67	7	of	of	IN
cord-017784-4r3fpmlb	67	8	patients	patient	NNS
cord-017784-4r3fpmlb	67	9	with	with	IN
cord-017784-4r3fpmlb	67	10	moderate	moderate	JJ
cord-017784-4r3fpmlb	67	11	to	to	IN
cord-017784-4r3fpmlb	67	12	severe	severe	JJ
cord-017784-4r3fpmlb	67	13	exacerbations	exacerbation	NNS
cord-017784-4r3fpmlb	67	14	do	do	VBP
cord-017784-4r3fpmlb	67	15	not	not	RB
cord-017784-4r3fpmlb	67	16	respond	respond	VB
cord-017784-4r3fpmlb	67	17	to	to	IN
cord-017784-4r3fpmlb	67	18	initial	initial	JJ
cord-017784-4r3fpmlb	67	19	empirical	empirical	JJ
cord-017784-4r3fpmlb	67	20	therapy	therapy	NN
cord-017784-4r3fpmlb	67	21	and	and	CC
cord-017784-4r3fpmlb	67	22	require	require	VB
cord-017784-4r3fpmlb	67	23	a	a	DT
cord-017784-4r3fpmlb	67	24	change	change	NN
cord-017784-4r3fpmlb	67	25	of	of	IN
cord-017784-4r3fpmlb	67	26	antibiotic	antibiotic	NN
cord-017784-4r3fpmlb	67	27	.	.	.
cord-017784-4r3fpmlb	68	1	In	in	IN
cord-017784-4r3fpmlb	68	2	these	these	DT
cord-017784-4r3fpmlb	68	3	cases	case	NNS
cord-017784-4r3fpmlb	68	4	,	,	,
cord-017784-4r3fpmlb	68	5	the	the	DT
cord-017784-4r3fpmlb	68	6	infection	infection	NN
cord-017784-4r3fpmlb	68	7	can	can	MD
cord-017784-4r3fpmlb	68	8	be	be	VB
cord-017784-4r3fpmlb	68	9	caused	cause	VBN
cord-017784-4r3fpmlb	68	10	by	by	IN
cord-017784-4r3fpmlb	68	11	Staphylococcus	Staphylococcus	NNP
cord-017784-4r3fpmlb	68	12	aureus	aureus	NN
cord-017784-4r3fpmlb	68	13	,	,	,
cord-017784-4r3fpmlb	68	14	P.	P.	NNP
cord-017784-4r3fpmlb	68	15	aeruginosa	aeruginosa	NN
cord-017784-4r3fpmlb	68	16	,	,	,
cord-017784-4r3fpmlb	68	17	or	or	CC
cord-017784-4r3fpmlb	68	18	some	some	DT
cord-017784-4r3fpmlb	68	19	atypical	atypical	JJ
cord-017784-4r3fpmlb	68	20	microorganism	microorganism	NN
cord-017784-4r3fpmlb	68	21	not	not	RB
cord-017784-4r3fpmlb	68	22	covered	cover	VBN
cord-017784-4r3fpmlb	68	23	by	by	IN
cord-017784-4r3fpmlb	68	24	the	the	DT
cord-017784-4r3fpmlb	68	25	initial	initial	JJ
cord-017784-4r3fpmlb	68	26	regimen	regimen	NN
cord-017784-4r3fpmlb	68	27	or	or	CC
cord-017784-4r3fpmlb	68	28	because	because	IN
cord-017784-4r3fpmlb	68	29	of	of	IN
cord-017784-4r3fpmlb	68	30	resistant	resistant	JJ
cord-017784-4r3fpmlb	68	31	organisms	organism	NNS
cord-017784-4r3fpmlb	68	32	(	(	-LRB-
cord-017784-4r3fpmlb	68	33	such	such	JJ
cord-017784-4r3fpmlb	68	34	as	as	IN
cord-017784-4r3fpmlb	68	35	S.	S.	NNP
cord-017784-4r3fpmlb	68	36	pneumoniae	pneumoniae	NN
cord-017784-4r3fpmlb	68	37	)	)	-RRB-
cord-017784-4r3fpmlb	68	38	;	;	:
cord-017784-4r3fpmlb	68	39	hence	hence	RB
cord-017784-4r3fpmlb	68	40	,	,	,
cord-017784-4r3fpmlb	68	41	a	a	DT
cord-017784-4r3fpmlb	68	42	microbiological	microbiological	JJ
cord-017784-4r3fpmlb	68	43	assessment	assessment	NN
cord-017784-4r3fpmlb	68	44	would	would	MD
cord-017784-4r3fpmlb	68	45	help	help	VB
cord-017784-4r3fpmlb	68	46	to	to	TO
cord-017784-4r3fpmlb	68	47	adjust	adjust	VB
cord-017784-4r3fpmlb	68	48	the	the	DT
cord-017784-4r3fpmlb	68	49	antibiotic	antibiotic	JJ
cord-017784-4r3fpmlb	68	50	treatment	treatment	NN
cord-017784-4r3fpmlb	68	51	of	of	IN
cord-017784-4r3fpmlb	68	52	second	second	JJ
cord-017784-4r3fpmlb	68	53	choice	choice	NN
cord-017784-4r3fpmlb	68	54	[	[	-LRB-
cord-017784-4r3fpmlb	68	55	17	17	CD
cord-017784-4r3fpmlb	68	56	]	]	-RRB-
cord-017784-4r3fpmlb	68	57	.	.	.
cord-017784-4r3fpmlb	69	1	There	there	EX
cord-017784-4r3fpmlb	69	2	are	be	VBP
cord-017784-4r3fpmlb	69	3	not	not	RB
cord-017784-4r3fpmlb	69	4	enough	enough	JJ
cord-017784-4r3fpmlb	69	5	data	datum	NNS
cord-017784-4r3fpmlb	69	6	concerning	concern	VBG
cord-017784-4r3fpmlb	69	7	the	the	DT
cord-017784-4r3fpmlb	69	8	role	role	NN
cord-017784-4r3fpmlb	69	9	of	of	IN
cord-017784-4r3fpmlb	69	10	antiviral	antiviral	JJ
cord-017784-4r3fpmlb	69	11	therapy	therapy	NN
cord-017784-4r3fpmlb	69	12	in	in	IN
cord-017784-4r3fpmlb	69	13	respiratory	respiratory	JJ
cord-017784-4r3fpmlb	69	14	failure	failure	NN
cord-017784-4r3fpmlb	69	15	due	due	IN
cord-017784-4r3fpmlb	69	16	to	to	IN
cord-017784-4r3fpmlb	69	17	COPD	COPD	NNP
cord-017784-4r3fpmlb	69	18	.	.	.
cord-017784-4r3fpmlb	70	1	There	there	EX
cord-017784-4r3fpmlb	70	2	are	be	VBP
cord-017784-4r3fpmlb	70	3	no	no	DT
cord-017784-4r3fpmlb	70	4	standard	standard	JJ
cord-017784-4r3fpmlb	70	5	procedures	procedure	NNS
cord-017784-4r3fpmlb	70	6	that	that	WDT
cord-017784-4r3fpmlb	70	7	determine	determine	VBP
cord-017784-4r3fpmlb	70	8	the	the	DT
cord-017784-4r3fpmlb	70	9	dose	dose	NN
cord-017784-4r3fpmlb	70	10	and	and	CC
cord-017784-4r3fpmlb	70	11	duration	duration	NN
cord-017784-4r3fpmlb	70	12	of	of	IN
cord-017784-4r3fpmlb	70	13	antibiotic	antibiotic	JJ
cord-017784-4r3fpmlb	70	14	treatment	treatment	NN
cord-017784-4r3fpmlb	70	15	in	in	IN
cord-017784-4r3fpmlb	70	16	patients	patient	NNS
cord-017784-4r3fpmlb	70	17	with	with	IN
cord-017784-4r3fpmlb	70	18	AECOPD	AECOPD	NNP
cord-017784-4r3fpmlb	70	19	.	.	.
cord-017784-4r3fpmlb	71	1	Therefore	therefore	RB
cord-017784-4r3fpmlb	71	2	,	,	,
cord-017784-4r3fpmlb	71	3	several	several	JJ
cord-017784-4r3fpmlb	71	4	studies	study	NNS
cord-017784-4r3fpmlb	71	5	demonstrate	demonstrate	VBP
cord-017784-4r3fpmlb	71	6	that	that	IN
cord-017784-4r3fpmlb	71	7	short	short	JJ
cord-017784-4r3fpmlb	71	8	-	-	HYPH
cord-017784-4r3fpmlb	71	9	term	term	NN
cord-017784-4r3fpmlb	71	10	antibiotic	antibiotic	JJ
cord-017784-4r3fpmlb	71	11	use	use	NN
cord-017784-4r3fpmlb	71	12	is	be	VBZ
cord-017784-4r3fpmlb	71	13	associated	associate	VBN
cord-017784-4r3fpmlb	71	14	with	with	IN
cord-017784-4r3fpmlb	71	15	very	very	RB
cord-017784-4r3fpmlb	71	16	important	important	JJ
cord-017784-4r3fpmlb	71	17	advantages	advantage	NNS
cord-017784-4r3fpmlb	71	18	such	such	JJ
cord-017784-4r3fpmlb	71	19	as	as	IN
cord-017784-4r3fpmlb	71	20	reduction	reduction	NN
cord-017784-4r3fpmlb	71	21	of	of	IN
cord-017784-4r3fpmlb	71	22	exposure	exposure	NN
cord-017784-4r3fpmlb	71	23	that	that	WDT
cord-017784-4r3fpmlb	71	24	will	will	MD
cord-017784-4r3fpmlb	71	25	result	result	VB
cord-017784-4r3fpmlb	71	26	in	in	IN
cord-017784-4r3fpmlb	71	27	decreased	decrease	VBN
cord-017784-4r3fpmlb	71	28	bacterial	bacterial	JJ
cord-017784-4r3fpmlb	71	29	resistance	resistance	NN
cord-017784-4r3fpmlb	71	30	,	,	,
cord-017784-4r3fpmlb	71	31	enhanced	enhanced	JJ
cord-017784-4r3fpmlb	71	32	compliance	compliance	NN
cord-017784-4r3fpmlb	71	33	,	,	,
cord-017784-4r3fpmlb	71	34	and	and	CC
cord-017784-4r3fpmlb	71	35	decreased	decrease	VBD
cord-017784-4r3fpmlb	71	36	side	side	JJ
cord-017784-4r3fpmlb	71	37	effects	effect	NNS
cord-017784-4r3fpmlb	71	38	.	.	.
cord-017784-4r3fpmlb	72	1	The	the	DT
cord-017784-4r3fpmlb	72	2	recommended	recommend	VBN
cord-017784-4r3fpmlb	72	3	length	length	NN
cord-017784-4r3fpmlb	72	4	of	of	IN
cord-017784-4r3fpmlb	72	5	antibiotics	antibiotic	NNS
cord-017784-4r3fpmlb	72	6	therapy	therapy	NN
cord-017784-4r3fpmlb	72	7	is	be	VBZ
cord-017784-4r3fpmlb	72	8	5	5	CD
cord-017784-4r3fpmlb	72	9	-	-	SYM
cord-017784-4r3fpmlb	72	10	7	7	CD
cord-017784-4r3fpmlb	72	11	days	day	NNS
cord-017784-4r3fpmlb	72	12	[	[	-LRB-
cord-017784-4r3fpmlb	72	13	10	10	CD
cord-017784-4r3fpmlb	72	14	]	]	-RRB-
cord-017784-4r3fpmlb	72	15	.	.	.
cord-017784-4r3fpmlb	73	1	The	the	DT
cord-017784-4r3fpmlb	73	2	incidence	incidence	NN
cord-017784-4r3fpmlb	73	3	of	of	IN
cord-017784-4r3fpmlb	73	4	community	community	NN
cord-017784-4r3fpmlb	73	5	-	-	HYPH
cord-017784-4r3fpmlb	73	6	acquired	acquire	VBN
cord-017784-4r3fpmlb	73	7	pneumonia	pneumonia	NN
cord-017784-4r3fpmlb	73	8	increases	increase	VBZ
cord-017784-4r3fpmlb	73	9	with	with	IN
cord-017784-4r3fpmlb	73	10	age	age	NN
cord-017784-4r3fpmlb	73	11	,	,	,
cord-017784-4r3fpmlb	73	12	reaching	reach	VBG
cord-017784-4r3fpmlb	73	13	25	25	CD
cord-017784-4r3fpmlb	73	14	-	-	SYM
cord-017784-4r3fpmlb	73	15	44	44	CD
cord-017784-4r3fpmlb	73	16	cases	case	NNS
cord-017784-4r3fpmlb	73	17	per	per	IN
cord-017784-4r3fpmlb	73	18	1000	1000	CD
cord-017784-4r3fpmlb	73	19	inhabitants	inhabitant	NNS
cord-017784-4r3fpmlb	73	20	/	/	SYM
cord-017784-4r3fpmlb	73	21	year	year	NN
cord-017784-4r3fpmlb	73	22	in	in	IN
cord-017784-4r3fpmlb	73	23	the	the	DT
cord-017784-4r3fpmlb	73	24	population	population	NN
cord-017784-4r3fpmlb	73	25	over	over	IN
cord-017784-4r3fpmlb	73	26	the	the	DT
cord-017784-4r3fpmlb	73	27	age	age	NN
cord-017784-4r3fpmlb	73	28	of	of	IN
cord-017784-4r3fpmlb	73	29	65	65	CD
cord-017784-4r3fpmlb	73	30	years	year	NNS
cord-017784-4r3fpmlb	73	31	,	,	,
cord-017784-4r3fpmlb	73	32	up	up	IN
cord-017784-4r3fpmlb	73	33	to	to	TO
cord-017784-4r3fpmlb	73	34	four	four	CD
cord-017784-4r3fpmlb	73	35	times	time	NNS
cord-017784-4r3fpmlb	73	36	that	that	DT
cord-017784-4r3fpmlb	73	37	of	of	IN
cord-017784-4r3fpmlb	73	38	younger	young	JJR
cord-017784-4r3fpmlb	73	39	patients	patient	NNS
cord-017784-4r3fpmlb	73	40	[	[	-LRB-
cord-017784-4r3fpmlb	73	41	18	18	CD
cord-017784-4r3fpmlb	73	42	]	]	-RRB-
cord-017784-4r3fpmlb	73	43	.	.	.
cord-017784-4r3fpmlb	74	1	Elderly	elderly	JJ
cord-017784-4r3fpmlb	74	2	patients	patient	NNS
cord-017784-4r3fpmlb	74	3	are	be	VBP
cord-017784-4r3fpmlb	74	4	more	more	RBR
cord-017784-4r3fpmlb	74	5	predisposed	predisposed	JJ
cord-017784-4r3fpmlb	74	6	to	to	IN
cord-017784-4r3fpmlb	74	7	pneumonia	pneumonia	NN
cord-017784-4r3fpmlb	74	8	because	because	IN
cord-017784-4r3fpmlb	74	9	of	of	IN
cord-017784-4r3fpmlb	74	10	their	-PRON-	PRP$
cord-017784-4r3fpmlb	74	11	impaired	impair	VBN
cord-017784-4r3fpmlb	74	12	gag	gag	NN
cord-017784-4r3fpmlb	74	13	reflex	reflex	NN
cord-017784-4r3fpmlb	74	14	,	,	,
cord-017784-4r3fpmlb	74	15	decreased	decrease	VBD
cord-017784-4r3fpmlb	74	16	mucociliary	mucociliary	JJ
cord-017784-4r3fpmlb	74	17	function	function	NN
cord-017784-4r3fpmlb	74	18	,	,	,
cord-017784-4r3fpmlb	74	19	waning	wane	VBG
cord-017784-4r3fpmlb	74	20	immunity	immunity	NN
cord-017784-4r3fpmlb	74	21	,	,	,
cord-017784-4r3fpmlb	74	22	impaired	impair	VBN
cord-017784-4r3fpmlb	74	23	febrile	febrile	JJ
cord-017784-4r3fpmlb	74	24	response	response	NN
cord-017784-4r3fpmlb	74	25	,	,	,
cord-017784-4r3fpmlb	74	26	and	and	CC
cord-017784-4r3fpmlb	74	27	chronic	chronic	JJ
cord-017784-4r3fpmlb	74	28	disease	disease	NN
cord-017784-4r3fpmlb	74	29	(	(	-LRB-
cord-017784-4r3fpmlb	74	30	diabetes	diabetes	NN
cord-017784-4r3fpmlb	74	31	mellitus	mellitus	NN
cord-017784-4r3fpmlb	74	32	,	,	,
cord-017784-4r3fpmlb	74	33	chronic	chronic	JJ
cord-017784-4r3fpmlb	74	34	obstructive	obstructive	JJ
cord-017784-4r3fpmlb	74	35	pulmonary	pulmonary	JJ
cord-017784-4r3fpmlb	74	36	disease	disease	NN
cord-017784-4r3fpmlb	74	37	,	,	,
cord-017784-4r3fpmlb	74	38	chronic	chronic	JJ
cord-017784-4r3fpmlb	74	39	heart	heart	NN
cord-017784-4r3fpmlb	74	40	failure	failure	NN
cord-017784-4r3fpmlb	74	41	,	,	,
cord-017784-4r3fpmlb	74	42	cancer	cancer	NN
cord-017784-4r3fpmlb	74	43	and	and	CC
cord-017784-4r3fpmlb	74	44	chronic	chronic	JJ
cord-017784-4r3fpmlb	74	45	renal	renal	JJ
cord-017784-4r3fpmlb	74	46	insufficiency	insufficiency	NN
cord-017784-4r3fpmlb	74	47	)	)	-RRB-
cord-017784-4r3fpmlb	74	48	.	.	.
cord-017784-4r3fpmlb	75	1	Furthermore	furthermore	RB
cord-017784-4r3fpmlb	75	2	,	,	,
cord-017784-4r3fpmlb	75	3	central	central	JJ
cord-017784-4r3fpmlb	75	4	nervous	nervous	JJ
cord-017784-4r3fpmlb	75	5	system	system	NN
cord-017784-4r3fpmlb	75	6	disorders	disorder	NNS
cord-017784-4r3fpmlb	75	7	and/or	and/or	CC
cord-017784-4r3fpmlb	75	8	an	an	DT
cord-017784-4r3fpmlb	75	9	impaired	impaired	JJ
cord-017784-4r3fpmlb	75	10	gag	gag	NN
cord-017784-4r3fpmlb	75	11	reflex	reflex	NN
cord-017784-4r3fpmlb	75	12	predispose	predispose	VB
cord-017784-4r3fpmlb	75	13	elderly	elderly	JJ
cord-017784-4r3fpmlb	75	14	patients	patient	NNS
cord-017784-4r3fpmlb	75	15	to	to	IN
cord-017784-4r3fpmlb	75	16	aspiration	aspiration	NN
cord-017784-4r3fpmlb	75	17	pneumonia	pneumonia	NN
cord-017784-4r3fpmlb	75	18	.	.	.
cord-017784-4r3fpmlb	76	1	With	with	IN
cord-017784-4r3fpmlb	76	2	respect	respect	NN
cord-017784-4r3fpmlb	76	3	to	to	IN
cord-017784-4r3fpmlb	76	4	the	the	DT
cord-017784-4r3fpmlb	76	5	youngest	young	JJS
cord-017784-4r3fpmlb	76	6	population	population	NN
cord-017784-4r3fpmlb	76	7	,	,	,
cord-017784-4r3fpmlb	76	8	pneumonia	pneumonia	NN
cord-017784-4r3fpmlb	76	9	in	in	IN
cord-017784-4r3fpmlb	76	10	the	the	DT
cord-017784-4r3fpmlb	76	11	elderly	elderly	JJ
cord-017784-4r3fpmlb	76	12	subjects	subject	NNS
cord-017784-4r3fpmlb	76	13	is	be	VBZ
cord-017784-4r3fpmlb	76	14	more	more	RBR
cord-017784-4r3fpmlb	76	15	severe	severe	JJ
cord-017784-4r3fpmlb	76	16	,	,	,
cord-017784-4r3fpmlb	76	17	requires	require	VBZ
cord-017784-4r3fpmlb	76	18	often	often	RB
cord-017784-4r3fpmlb	76	19	hospitalization	hospitalization	NN
cord-017784-4r3fpmlb	76	20	,	,	,
cord-017784-4r3fpmlb	76	21	and	and	CC
cord-017784-4r3fpmlb	76	22	is	be	VBZ
cord-017784-4r3fpmlb	76	23	characterized	characterize	VBN
cord-017784-4r3fpmlb	76	24	by	by	IN
cord-017784-4r3fpmlb	76	25	a	a	DT
cord-017784-4r3fpmlb	76	26	longer	long	JJR
cord-017784-4r3fpmlb	76	27	length	length	NN
cord-017784-4r3fpmlb	76	28	of	of	IN
cord-017784-4r3fpmlb	76	29	stay	stay	NN
cord-017784-4r3fpmlb	76	30	and	and	CC
cord-017784-4r3fpmlb	76	31	by	by	IN
cord-017784-4r3fpmlb	76	32	greater	great	JJR
cord-017784-4r3fpmlb	76	33	mortality	mortality	NN
cord-017784-4r3fpmlb	76	34	,	,	,
cord-017784-4r3fpmlb	76	35	particularly	particularly	RB
cord-017784-4r3fpmlb	76	36	in	in	IN
cord-017784-4r3fpmlb	76	37	patients	patient	NNS
cord-017784-4r3fpmlb	76	38	with	with	IN
cord-017784-4r3fpmlb	76	39	comorbidities	comorbiditie	NNS
cord-017784-4r3fpmlb	76	40	[	[	-LRB-
cord-017784-4r3fpmlb	76	41	19	19	CD
cord-017784-4r3fpmlb	76	42	]	]	-RRB-
cord-017784-4r3fpmlb	76	43	.	.	.
cord-017784-4r3fpmlb	77	1	It	-PRON-	PRP
cord-017784-4r3fpmlb	77	2	is	be	VBZ
cord-017784-4r3fpmlb	77	3	important	important	JJ
cord-017784-4r3fpmlb	77	4	to	to	TO
cord-017784-4r3fpmlb	77	5	remember	remember	VB
cord-017784-4r3fpmlb	77	6	that	that	IN
cord-017784-4r3fpmlb	77	7	clinical	clinical	JJ
cord-017784-4r3fpmlb	77	8	presentation	presentation	NN
cord-017784-4r3fpmlb	77	9	of	of	IN
cord-017784-4r3fpmlb	77	10	pneumonia	pneumonia	NN
cord-017784-4r3fpmlb	77	11	in	in	IN
cord-017784-4r3fpmlb	77	12	the	the	DT
cord-017784-4r3fpmlb	77	13	elderly	elderly	JJ
cord-017784-4r3fpmlb	77	14	may	may	MD
cord-017784-4r3fpmlb	77	15	be	be	VB
cord-017784-4r3fpmlb	77	16	subtle	subtle	JJ
cord-017784-4r3fpmlb	77	17	and	and	CC
cord-017784-4r3fpmlb	77	18	may	may	MD
cord-017784-4r3fpmlb	77	19	be	be	VB
cord-017784-4r3fpmlb	77	20	afebrile	afebrile	JJ
cord-017784-4r3fpmlb	77	21	.	.	.
cord-017784-4r3fpmlb	78	1	Altered	alter	VBN
cord-017784-4r3fpmlb	78	2	mental	mental	JJ
cord-017784-4r3fpmlb	78	3	status	status	NN
cord-017784-4r3fpmlb	78	4	,	,	,
cord-017784-4r3fpmlb	78	5	a	a	DT
cord-017784-4r3fpmlb	78	6	sudden	sudden	JJ
cord-017784-4r3fpmlb	78	7	decline	decline	NN
cord-017784-4r3fpmlb	78	8	in	in	IN
cord-017784-4r3fpmlb	78	9	functional	functional	JJ
cord-017784-4r3fpmlb	78	10	capacity	capacity	NN
cord-017784-4r3fpmlb	78	11	,	,	,
cord-017784-4r3fpmlb	78	12	worsening	worsen	VBG
cord-017784-4r3fpmlb	78	13	of	of	IN
cord-017784-4r3fpmlb	78	14	underlying	underlie	VBG
cord-017784-4r3fpmlb	78	15	diseases	disease	NNS
cord-017784-4r3fpmlb	78	16	,	,	,
cord-017784-4r3fpmlb	78	17	and	and	CC
cord-017784-4r3fpmlb	78	18	falls	fall	VBZ
cord-017784-4r3fpmlb	78	19	may	may	MD
cord-017784-4r3fpmlb	78	20	be	be	VB
cord-017784-4r3fpmlb	78	21	the	the	DT
cord-017784-4r3fpmlb	78	22	only	only	JJ
cord-017784-4r3fpmlb	78	23	findings	finding	NNS
cord-017784-4r3fpmlb	78	24	.	.	.
cord-017784-4r3fpmlb	79	1	As	as	IN
cord-017784-4r3fpmlb	79	2	stated	state	VBN
cord-017784-4r3fpmlb	79	3	by	by	IN
cord-017784-4r3fpmlb	79	4	Sir	Sir	NNP
cord-017784-4r3fpmlb	79	5	William	William	NNP
cord-017784-4r3fpmlb	79	6	Osler	Osler	NNP
cord-017784-4r3fpmlb	79	7	[	[	-LRB-
cord-017784-4r3fpmlb	79	8	20	20	CD
cord-017784-4r3fpmlb	79	9	]	]	-RRB-
cord-017784-4r3fpmlb	79	10	"	"	``
cord-017784-4r3fpmlb	79	11	in	in	IN
cord-017784-4r3fpmlb	79	12	old	old	JJ
cord-017784-4r3fpmlb	79	13	age	age	NN
cord-017784-4r3fpmlb	79	14	,	,	,
cord-017784-4r3fpmlb	79	15	pneumonia	pneumonia	NN
cord-017784-4r3fpmlb	79	16	may	may	MD
cord-017784-4r3fpmlb	79	17	be	be	VB
cord-017784-4r3fpmlb	79	18	latent	latent	JJ
cord-017784-4r3fpmlb	79	19	,	,	,
cord-017784-4r3fpmlb	79	20	coming	come	VBG
cord-017784-4r3fpmlb	79	21	on	on	RP
cord-017784-4r3fpmlb	79	22	without	without	IN
cord-017784-4r3fpmlb	79	23	chill	chill	NN
cord-017784-4r3fpmlb	79	24	,	,	,
cord-017784-4r3fpmlb	79	25	the	the	DT
cord-017784-4r3fpmlb	79	26	cough	cough	NN
cord-017784-4r3fpmlb	79	27	and	and	CC
cord-017784-4r3fpmlb	79	28	expectoration	expectoration	NN
cord-017784-4r3fpmlb	79	29	are	be	VBP
cord-017784-4r3fpmlb	79	30	slight	slight	JJ
cord-017784-4r3fpmlb	79	31	,	,	,
cord-017784-4r3fpmlb	79	32	the	the	DT
cord-017784-4r3fpmlb	79	33	physical	physical	JJ
cord-017784-4r3fpmlb	79	34	signs	sign	NNS
cord-017784-4r3fpmlb	79	35	ill	ill	RB
cord-017784-4r3fpmlb	79	36	defined	defined	JJ
cord-017784-4r3fpmlb	79	37	and	and	CC
cord-017784-4r3fpmlb	79	38	changeable	changeable	JJ
cord-017784-4r3fpmlb	79	39	,	,	,
cord-017784-4r3fpmlb	79	40	and	and	CC
cord-017784-4r3fpmlb	79	41	the	the	DT
cord-017784-4r3fpmlb	79	42	constitutional	constitutional	JJ
cord-017784-4r3fpmlb	79	43	symptoms	symptom	NNS
cord-017784-4r3fpmlb	79	44	out	out	IN
cord-017784-4r3fpmlb	79	45	of	of	IN
cord-017784-4r3fpmlb	79	46	all	all	DT
cord-017784-4r3fpmlb	79	47	proportion	proportion	NN
cord-017784-4r3fpmlb	79	48	.	.	.
cord-017784-4r3fpmlb	80	1	"	"	''
cord-017784-4r3fpmlb	81	1	As	as	IN
cord-017784-4r3fpmlb	81	2	with	with	IN
cord-017784-4r3fpmlb	81	3	any	any	DT
cord-017784-4r3fpmlb	81	4	infectious	infectious	JJ
cord-017784-4r3fpmlb	81	5	disease	disease	NN
cord-017784-4r3fpmlb	81	6	,	,	,
cord-017784-4r3fpmlb	81	7	identifying	identify	VBG
cord-017784-4r3fpmlb	81	8	the	the	DT
cord-017784-4r3fpmlb	81	9	causative	causative	JJ
cord-017784-4r3fpmlb	81	10	agent	agent	NN
cord-017784-4r3fpmlb	81	11	in	in	IN
cord-017784-4r3fpmlb	81	12	CAP	CAP	NNP
cord-017784-4r3fpmlb	81	13	can	can	MD
cord-017784-4r3fpmlb	81	14	be	be	VB
cord-017784-4r3fpmlb	81	15	extremely	extremely	RB
cord-017784-4r3fpmlb	81	16	useful	useful	JJ
cord-017784-4r3fpmlb	81	17	in	in	IN
cord-017784-4r3fpmlb	81	18	guiding	guide	VBG
cord-017784-4r3fpmlb	81	19	antimicrobial	antimicrobial	JJ
cord-017784-4r3fpmlb	81	20	therapy	therapy	NN
cord-017784-4r3fpmlb	81	21	.	.	.
cord-017784-4r3fpmlb	82	1	Unfortunately	unfortunately	RB
cord-017784-4r3fpmlb	82	2	,	,	,
cord-017784-4r3fpmlb	82	3	despite	despite	IN
cord-017784-4r3fpmlb	82	4	the	the	DT
cord-017784-4r3fpmlb	82	5	use	use	NN
cord-017784-4r3fpmlb	82	6	of	of	IN
cord-017784-4r3fpmlb	82	7	more	more	RBR
cord-017784-4r3fpmlb	82	8	sensitive	sensitive	JJ
cord-017784-4r3fpmlb	82	9	and	and	CC
cord-017784-4r3fpmlb	82	10	specific	specific	JJ
cord-017784-4r3fpmlb	82	11	diagnostic	diagnostic	JJ
cord-017784-4r3fpmlb	82	12	methods	method	NNS
cord-017784-4r3fpmlb	82	13	to	to	TO
cord-017784-4r3fpmlb	82	14	define	define	VB
cord-017784-4r3fpmlb	82	15	an	an	DT
cord-017784-4r3fpmlb	82	16	etiologic	etiologic	JJ
cord-017784-4r3fpmlb	82	17	pathogen	pathogen	NN
cord-017784-4r3fpmlb	82	18	in	in	IN
cord-017784-4r3fpmlb	82	19	community	community	NN
cord-017784-4r3fpmlb	82	20	-	-	HYPH
cord-017784-4r3fpmlb	82	21	acquired	acquire	VBN
cord-017784-4r3fpmlb	82	22	pneumonia	pneumonia	NN
cord-017784-4r3fpmlb	82	23	requiring	require	VBG
cord-017784-4r3fpmlb	82	24	hospitalization	hospitalization	NN
cord-017784-4r3fpmlb	82	25	,	,	,
cord-017784-4r3fpmlb	82	26	in	in	IN
cord-017784-4r3fpmlb	82	27	the	the	DT
cord-017784-4r3fpmlb	82	28	majority	majority	NN
cord-017784-4r3fpmlb	82	29	of	of	IN
cord-017784-4r3fpmlb	82	30	patients	patient	NNS
cord-017784-4r3fpmlb	82	31	,	,	,
cord-017784-4r3fpmlb	82	32	a	a	DT
cord-017784-4r3fpmlb	82	33	microbiologic	microbiologic	JJ
cord-017784-4r3fpmlb	82	34	diagnosis	diagnosis	NN
cord-017784-4r3fpmlb	82	35	can	can	MD
cord-017784-4r3fpmlb	82	36	not	not	RB
cord-017784-4r3fpmlb	82	37	be	be	VB
cord-017784-4r3fpmlb	82	38	made	make	VBN
cord-017784-4r3fpmlb	82	39	[	[	-LRB-
cord-017784-4r3fpmlb	82	40	21	21	CD
cord-017784-4r3fpmlb	82	41	]	]	-RRB-
cord-017784-4r3fpmlb	82	42	.	.	.
cord-017784-4r3fpmlb	83	1	In	in	IN
cord-017784-4r3fpmlb	83	2	most	most	JJS
cord-017784-4r3fpmlb	83	3	cases	case	NNS
cord-017784-4r3fpmlb	83	4	,	,	,
cord-017784-4r3fpmlb	83	5	the	the	DT
cord-017784-4r3fpmlb	83	6	microbiologic	microbiologic	JJ
cord-017784-4r3fpmlb	83	7	patterns	pattern	NNS
cord-017784-4r3fpmlb	83	8	observed	observe	VBN
cord-017784-4r3fpmlb	83	9	in	in	IN
cord-017784-4r3fpmlb	83	10	the	the	DT
cord-017784-4r3fpmlb	83	11	elderly	elderly	JJ
cord-017784-4r3fpmlb	83	12	do	do	VBP
cord-017784-4r3fpmlb	83	13	not	not	RB
cord-017784-4r3fpmlb	83	14	differ	differ	VB
cord-017784-4r3fpmlb	83	15	significantly	significantly	RB
cord-017784-4r3fpmlb	83	16	from	from	IN
cord-017784-4r3fpmlb	83	17	those	those	DT
cord-017784-4r3fpmlb	83	18	observed	observe	VBN
cord-017784-4r3fpmlb	83	19	in	in	IN
cord-017784-4r3fpmlb	83	20	younger	young	JJR
cord-017784-4r3fpmlb	83	21	populations	population	NNS
cord-017784-4r3fpmlb	83	22	although	although	IN
cord-017784-4r3fpmlb	83	23	with	with	IN
cord-017784-4r3fpmlb	83	24	a	a	DT
cord-017784-4r3fpmlb	83	25	different	different	JJ
cord-017784-4r3fpmlb	83	26	age	age	NN
cord-017784-4r3fpmlb	83	27	-	-	HYPH
cord-017784-4r3fpmlb	83	28	related	relate	VBN
cord-017784-4r3fpmlb	83	29	distribution	distribution	NN
cord-017784-4r3fpmlb	83	30	.	.	.
cord-017784-4r3fpmlb	84	1	Streptococcus	streptococcus	NN
cord-017784-4r3fpmlb	84	2	pneumoniae	pneumoniae	NN
cord-017784-4r3fpmlb	84	3	is	be	VBZ
cord-017784-4r3fpmlb	84	4	still	still	RB
cord-017784-4r3fpmlb	84	5	the	the	DT
cord-017784-4r3fpmlb	84	6	most	most	RBS
cord-017784-4r3fpmlb	84	7	important	important	JJ
cord-017784-4r3fpmlb	84	8	pathogen	pathogen	NN
cord-017784-4r3fpmlb	84	9	in	in	IN
cord-017784-4r3fpmlb	84	10	younger	young	JJR
cord-017784-4r3fpmlb	84	11	as	as	RB
cord-017784-4r3fpmlb	84	12	well	well	RB
cord-017784-4r3fpmlb	84	13	as	as	IN
cord-017784-4r3fpmlb	84	14	older	old	JJR
cord-017784-4r3fpmlb	84	15	adults	adult	NNS
cord-017784-4r3fpmlb	84	16	and	and	CC
cord-017784-4r3fpmlb	84	17	the	the	DT
cord-017784-4r3fpmlb	84	18	incidence	incidence	NN
cord-017784-4r3fpmlb	84	19	of	of	IN
cord-017784-4r3fpmlb	84	20	pneumococcal	pneumococcal	JJ
cord-017784-4r3fpmlb	84	21	pneumonia	pneumonia	NN
cord-017784-4r3fpmlb	84	22	generally	generally	RB
cord-017784-4r3fpmlb	84	23	increases	increase	VBZ
cord-017784-4r3fpmlb	84	24	with	with	IN
cord-017784-4r3fpmlb	84	25	age	age	NN
cord-017784-4r3fpmlb	84	26	.	.	.
cord-017784-4r3fpmlb	85	1	Haemophilus	haemophilus	JJ
cord-017784-4r3fpmlb	85	2	influenzae	influenzae	NN
cord-017784-4r3fpmlb	85	3	is	be	VBZ
cord-017784-4r3fpmlb	85	4	relatively	relatively	RB
cord-017784-4r3fpmlb	85	5	more	more	RBR
cord-017784-4r3fpmlb	85	6	common	common	JJ
cord-017784-4r3fpmlb	85	7	in	in	IN
cord-017784-4r3fpmlb	85	8	elderly	elderly	JJ
cord-017784-4r3fpmlb	85	9	patients	patient	NNS
cord-017784-4r3fpmlb	85	10	than	than	IN
cord-017784-4r3fpmlb	85	11	in	in	IN
cord-017784-4r3fpmlb	85	12	non	non	JJ
cord-017784-4r3fpmlb	85	13	-	-	JJ
cord-017784-4r3fpmlb	85	14	elderly	elderly	JJ
cord-017784-4r3fpmlb	85	15	adults	adult	NNS
cord-017784-4r3fpmlb	85	16	and	and	CC
cord-017784-4r3fpmlb	85	17	are	be	VBP
cord-017784-4r3fpmlb	85	18	the	the	DT
cord-017784-4r3fpmlb	85	19	second	second	JJ
cord-017784-4r3fpmlb	85	20	most	most	RBS
cord-017784-4r3fpmlb	85	21	frequently	frequently	RB
cord-017784-4r3fpmlb	85	22	identified	identify	VBN
cord-017784-4r3fpmlb	85	23	microorganisms	microorganism	NNS
cord-017784-4r3fpmlb	85	24	,	,	,
cord-017784-4r3fpmlb	85	25	while	while	IN
cord-017784-4r3fpmlb	85	26	Moraxella	Moraxella	NNP
cord-017784-4r3fpmlb	85	27	catarrhalis	catarrhalis	NNP
cord-017784-4r3fpmlb	85	28	is	be	VBZ
cord-017784-4r3fpmlb	85	29	of	of	IN
cord-017784-4r3fpmlb	85	30	particular	particular	JJ
cord-017784-4r3fpmlb	85	31	importance	importance	NN
cord-017784-4r3fpmlb	85	32	as	as	IN
cord-017784-4r3fpmlb	85	33	a	a	DT
cord-017784-4r3fpmlb	85	34	cause	cause	NN
cord-017784-4r3fpmlb	85	35	of	of	IN
cord-017784-4r3fpmlb	85	36	community	community	NN
cord-017784-4r3fpmlb	85	37	-	-	HYPH
cord-017784-4r3fpmlb	85	38	acquired	acquire	VBN
cord-017784-4r3fpmlb	85	39	pneumonia	pneumonia	NN
cord-017784-4r3fpmlb	85	40	in	in	IN
cord-017784-4r3fpmlb	85	41	patients	patient	NNS
cord-017784-4r3fpmlb	85	42	with	with	IN
cord-017784-4r3fpmlb	85	43	chronic	chronic	JJ
cord-017784-4r3fpmlb	85	44	bronchitis	bronchitis	NN
cord-017784-4r3fpmlb	85	45	.	.	.
cord-017784-4r3fpmlb	86	1	The	the	DT
cord-017784-4r3fpmlb	86	2	most	most	RBS
cord-017784-4r3fpmlb	86	3	discernible	discernible	JJ
cord-017784-4r3fpmlb	86	4	differences	difference	NNS
cord-017784-4r3fpmlb	86	5	between	between	IN
cord-017784-4r3fpmlb	86	6	the	the	DT
cord-017784-4r3fpmlb	86	7	two	two	CD
cord-017784-4r3fpmlb	86	8	groups	group	NNS
cord-017784-4r3fpmlb	86	9	were	be	VBD
cord-017784-4r3fpmlb	86	10	Gram	gram	NN
cord-017784-4r3fpmlb	86	11	-	-	HYPH
cord-017784-4r3fpmlb	86	12	negatives	negative	NNS
cord-017784-4r3fpmlb	86	13	,	,	,
cord-017784-4r3fpmlb	86	14	especially	especially	RB
cord-017784-4r3fpmlb	86	15	Enterobacteriaceae	Enterobacteriaceae	NNP
cord-017784-4r3fpmlb	86	16	were	be	VBD
cord-017784-4r3fpmlb	86	17	found	find	VBN
cord-017784-4r3fpmlb	86	18	more	more	RBR
cord-017784-4r3fpmlb	86	19	frequently	frequently	RB
cord-017784-4r3fpmlb	86	20	in	in	IN
cord-017784-4r3fpmlb	86	21	the	the	DT
cord-017784-4r3fpmlb	86	22	elderly	elderly	JJ
cord-017784-4r3fpmlb	86	23	,	,	,
cord-017784-4r3fpmlb	86	24	whereas	whereas	IN
cord-017784-4r3fpmlb	86	25	certain	certain	JJ
cord-017784-4r3fpmlb	86	26	atypical	atypical	JJ
cord-017784-4r3fpmlb	86	27	pathogens	pathogen	NNS
cord-017784-4r3fpmlb	86	28	(	(	-LRB-
cord-017784-4r3fpmlb	86	29	Legionella	Legionella	NNP
cord-017784-4r3fpmlb	86	30	pneumophila	pneumophila	NN
cord-017784-4r3fpmlb	86	31	,	,	,
cord-017784-4r3fpmlb	86	32	Mycoplasma	mycoplasma	NN
cord-017784-4r3fpmlb	86	33	pneumoniae	pneumoniae	NN
cord-017784-4r3fpmlb	86	34	,	,	,
cord-017784-4r3fpmlb	86	35	and	and	CC
cord-017784-4r3fpmlb	86	36	Coxiella	Coxiella	NNP
cord-017784-4r3fpmlb	86	37	burnetii	burnetii	NNP
cord-017784-4r3fpmlb	86	38	)	)	-RRB-
cord-017784-4r3fpmlb	86	39	were	be	VBD
cord-017784-4r3fpmlb	86	40	more	more	RBR
cord-017784-4r3fpmlb	86	41	frequent	frequent	JJ
cord-017784-4r3fpmlb	86	42	in	in	IN
cord-017784-4r3fpmlb	86	43	younger	young	JJR
cord-017784-4r3fpmlb	86	44	patient	patient	JJ
cord-017784-4r3fpmlb	86	45	[	[	-LRB-
cord-017784-4r3fpmlb	86	46	22	22	CD
cord-017784-4r3fpmlb	86	47	]	]	-RRB-
cord-017784-4r3fpmlb	86	48	.	.	.
cord-017784-4r3fpmlb	87	1	Among	among	IN
cord-017784-4r3fpmlb	87	2	the	the	DT
cord-017784-4r3fpmlb	87	3	atypical	atypical	JJ
cord-017784-4r3fpmlb	87	4	bacteria	bacteria	NNS
cord-017784-4r3fpmlb	87	5	,	,	,
cord-017784-4r3fpmlb	87	6	Chlamydophila	Chlamydophila	NNP
cord-017784-4r3fpmlb	87	7	pneumoniae	pneumoniae	NN
cord-017784-4r3fpmlb	87	8	is	be	VBZ
cord-017784-4r3fpmlb	87	9	the	the	DT
cord-017784-4r3fpmlb	87	10	most	most	RBS
cord-017784-4r3fpmlb	87	11	common	common	JJ
cord-017784-4r3fpmlb	87	12	agent	agent	NN
cord-017784-4r3fpmlb	87	13	,	,	,
cord-017784-4r3fpmlb	87	14	while	while	IN
cord-017784-4r3fpmlb	87	15	Mycoplasma	Mycoplasma	NNP
cord-017784-4r3fpmlb	87	16	pneumoniae	pneumoniae	NN
cord-017784-4r3fpmlb	87	17	is	be	VBZ
cord-017784-4r3fpmlb	87	18	less	less	RBR
cord-017784-4r3fpmlb	87	19	frequently	frequently	RB
cord-017784-4r3fpmlb	87	20	associated	associate	VBN
cord-017784-4r3fpmlb	87	21	with	with	IN
cord-017784-4r3fpmlb	87	22	CAP	cap	NN
cord-017784-4r3fpmlb	87	23	in	in	IN
cord-017784-4r3fpmlb	87	24	this	this	DT
cord-017784-4r3fpmlb	87	25	age	age	NN
cord-017784-4r3fpmlb	87	26	group	group	NN
cord-017784-4r3fpmlb	87	27	.	.	.
cord-017784-4r3fpmlb	88	1	Although	although	IN
cord-017784-4r3fpmlb	88	2	uncommon	uncommon	JJ
cord-017784-4r3fpmlb	88	3	,	,	,
cord-017784-4r3fpmlb	88	4	Legionella	Legionella	NNP
cord-017784-4r3fpmlb	88	5	pneumophila	pneumophila	NN
cord-017784-4r3fpmlb	88	6	should	should	MD
cord-017784-4r3fpmlb	88	7	be	be	VB
cord-017784-4r3fpmlb	88	8	considered	consider	VBN
cord-017784-4r3fpmlb	88	9	in	in	IN
cord-017784-4r3fpmlb	88	10	elderly	elderly	JJ
cord-017784-4r3fpmlb	88	11	adults	adult	NNS
cord-017784-4r3fpmlb	88	12	presenting	present	VBG
cord-017784-4r3fpmlb	88	13	with	with	IN
cord-017784-4r3fpmlb	88	14	atypical	atypical	JJ
cord-017784-4r3fpmlb	88	15	symptoms	symptom	NNS
cord-017784-4r3fpmlb	88	16	(	(	-LRB-
cord-017784-4r3fpmlb	88	17	e.g.	e.g.	RB
cord-017784-4r3fpmlb	88	18	,	,	,
cord-017784-4r3fpmlb	88	19	headache	headache	NN
cord-017784-4r3fpmlb	88	20	,	,	,
cord-017784-4r3fpmlb	88	21	weakness	weakness	NN
cord-017784-4r3fpmlb	88	22	,	,	,
cord-017784-4r3fpmlb	88	23	altered	alter	VBN
cord-017784-4r3fpmlb	88	24	mental	mental	JJ
cord-017784-4r3fpmlb	88	25	status	status	NN
cord-017784-4r3fpmlb	88	26	,	,	,
cord-017784-4r3fpmlb	88	27	gastrointestinal	gastrointestinal	JJ
cord-017784-4r3fpmlb	88	28	disturbances	disturbance	NNS
cord-017784-4r3fpmlb	88	29	,	,	,
cord-017784-4r3fpmlb	88	30	or	or	CC
cord-017784-4r3fpmlb	88	31	bradycardia	bradycardia	JJ
cord-017784-4r3fpmlb	88	32	in	in	IN
cord-017784-4r3fpmlb	88	33	the	the	DT
cord-017784-4r3fpmlb	88	34	setting	setting	NN
cord-017784-4r3fpmlb	88	35	of	of	IN
cord-017784-4r3fpmlb	88	36	a	a	DT
cord-017784-4r3fpmlb	88	37	paucity	paucity	NN
cord-017784-4r3fpmlb	88	38	of	of	IN
cord-017784-4r3fpmlb	88	39	respiratory	respiratory	JJ
cord-017784-4r3fpmlb	88	40	symptoms	symptom	NNS
cord-017784-4r3fpmlb	88	41	)	)	-RRB-
cord-017784-4r3fpmlb	88	42	or	or	CC
cord-017784-4r3fpmlb	88	43	those	those	DT
cord-017784-4r3fpmlb	88	44	with	with	IN
cord-017784-4r3fpmlb	88	45	severe	severe	JJ
cord-017784-4r3fpmlb	88	46	pneumonia	pneumonia	NN
cord-017784-4r3fpmlb	88	47	.	.	.
cord-017784-4r3fpmlb	89	1	Gram	gram	NN
cord-017784-4r3fpmlb	89	2	-	-	HYPH
cord-017784-4r3fpmlb	89	3	negative	negative	JJ
cord-017784-4r3fpmlb	89	4	organisms	organism	NNS
cord-017784-4r3fpmlb	89	5	are	be	VBP
cord-017784-4r3fpmlb	89	6	an	an	DT
cord-017784-4r3fpmlb	89	7	uncommon	uncommon	JJ
cord-017784-4r3fpmlb	89	8	cause	cause	NN
cord-017784-4r3fpmlb	89	9	of	of	IN
cord-017784-4r3fpmlb	89	10	CAP	cap	NN
cord-017784-4r3fpmlb	89	11	.	.	.
cord-017784-4r3fpmlb	90	1	However	however	RB
cord-017784-4r3fpmlb	90	2	,	,	,
cord-017784-4r3fpmlb	90	3	in	in	IN
cord-017784-4r3fpmlb	90	4	severely	severely	RB
cord-017784-4r3fpmlb	90	5	debilitated	debilitated	JJ
cord-017784-4r3fpmlb	90	6	or	or	CC
cord-017784-4r3fpmlb	90	7	chronically	chronically	RB
cord-017784-4r3fpmlb	90	8	ill	ill	JJ
cord-017784-4r3fpmlb	90	9	elderly	elderly	JJ
cord-017784-4r3fpmlb	90	10	patients	patient	NNS
cord-017784-4r3fpmlb	90	11	from	from	IN
cord-017784-4r3fpmlb	90	12	the	the	DT
cord-017784-4r3fpmlb	90	13	community	community	NN
cord-017784-4r3fpmlb	90	14	,	,	,
cord-017784-4r3fpmlb	90	15	a	a	DT
cord-017784-4r3fpmlb	90	16	high	high	JJ
cord-017784-4r3fpmlb	90	17	index	index	NN
cord-017784-4r3fpmlb	90	18	of	of	IN
cord-017784-4r3fpmlb	90	19	suspicion	suspicion	NN
cord-017784-4r3fpmlb	90	20	for	for	IN
cord-017784-4r3fpmlb	90	21	Gram	gram	NN
cord-017784-4r3fpmlb	90	22	-	-	HYPH
cord-017784-4r3fpmlb	90	23	negative	negative	JJ
cord-017784-4r3fpmlb	90	24	bacilli	bacilli	NN
cord-017784-4r3fpmlb	90	25	may	may	MD
cord-017784-4r3fpmlb	90	26	be	be	VB
cord-017784-4r3fpmlb	90	27	warranted	warrant	VBN
cord-017784-4r3fpmlb	90	28	,	,	,
cord-017784-4r3fpmlb	90	29	especially	especially	RB
cord-017784-4r3fpmlb	90	30	in	in	IN
cord-017784-4r3fpmlb	90	31	those	those	DT
cord-017784-4r3fpmlb	90	32	who	who	WP
cord-017784-4r3fpmlb	90	33	fail	fail	VBP
cord-017784-4r3fpmlb	90	34	to	to	TO
cord-017784-4r3fpmlb	90	35	improve	improve	VB
cord-017784-4r3fpmlb	90	36	on	on	IN
cord-017784-4r3fpmlb	90	37	standard	standard	JJ
cord-017784-4r3fpmlb	90	38	therapy	therapy	NN
cord-017784-4r3fpmlb	90	39	.	.	.
cord-017784-4r3fpmlb	91	1	The	the	DT
cord-017784-4r3fpmlb	91	2	probability	probability	NN
cord-017784-4r3fpmlb	91	3	of	of	IN
cord-017784-4r3fpmlb	91	4	MRSA	MRSA	NNP
cord-017784-4r3fpmlb	91	5	in	in	IN
cord-017784-4r3fpmlb	91	6	patients	patient	NNS
cord-017784-4r3fpmlb	91	7	hospitalized	hospitalize	VBN
cord-017784-4r3fpmlb	91	8	in	in	IN
cord-017784-4r3fpmlb	91	9	conventional	conventional	JJ
cord-017784-4r3fpmlb	91	10	wards	ward	NNS
cord-017784-4r3fpmlb	91	11	is	be	VBZ
cord-017784-4r3fpmlb	91	12	low	low	JJ
cord-017784-4r3fpmlb	91	13	being	be	VBG
cord-017784-4r3fpmlb	91	14	more	more	RBR
cord-017784-4r3fpmlb	91	15	frequent	frequent	JJ
cord-017784-4r3fpmlb	91	16	in	in	IN
cord-017784-4r3fpmlb	91	17	severe	severe	JJ
cord-017784-4r3fpmlb	91	18	CAP	cap	NN
cord-017784-4r3fpmlb	91	19	understood	understand	VBD
cord-017784-4r3fpmlb	91	20	as	as	IN
cord-017784-4r3fpmlb	91	21	the	the	DT
cord-017784-4r3fpmlb	91	22	need	need	NN
cord-017784-4r3fpmlb	91	23	for	for	IN
cord-017784-4r3fpmlb	91	24	admission	admission	NN
cord-017784-4r3fpmlb	91	25	in	in	IN
cord-017784-4r3fpmlb	91	26	an	an	DT
cord-017784-4r3fpmlb	91	27	intensive	intensive	JJ
cord-017784-4r3fpmlb	91	28	care	care	NN
cord-017784-4r3fpmlb	91	29	unit	unit	NN
cord-017784-4r3fpmlb	91	30	(	(	-LRB-
cord-017784-4r3fpmlb	91	31	ICU	ICU	NNP
cord-017784-4r3fpmlb	91	32	)	)	-RRB-
cord-017784-4r3fpmlb	91	33	.	.	.
cord-017784-4r3fpmlb	92	1	Thus	thus	RB
cord-017784-4r3fpmlb	92	2	,	,	,
cord-017784-4r3fpmlb	92	3	in	in	IN
cord-017784-4r3fpmlb	92	4	the	the	DT
cord-017784-4r3fpmlb	92	5	presence	presence	NN
cord-017784-4r3fpmlb	92	6	of	of	IN
cord-017784-4r3fpmlb	92	7	less	less	JJR
cord-017784-4r3fpmlb	92	8	than	than	IN
cord-017784-4r3fpmlb	92	9	two	two	CD
cord-017784-4r3fpmlb	92	10	factors	factor	NNS
cord-017784-4r3fpmlb	92	11	of	of	IN
cord-017784-4r3fpmlb	92	12	multiresistance	multiresistance	NN
cord-017784-4r3fpmlb	92	13	(	(	-LRB-
cord-017784-4r3fpmlb	92	14	severe	severe	JJ
cord-017784-4r3fpmlb	92	15	pneumonia	pneumonia	NN
cord-017784-4r3fpmlb	92	16	,	,	,
cord-017784-4r3fpmlb	92	17	hospitalization	hospitalization	NN
cord-017784-4r3fpmlb	92	18	in	in	IN
cord-017784-4r3fpmlb	92	19	the	the	DT
cord-017784-4r3fpmlb	92	20	previous	previous	JJ
cord-017784-4r3fpmlb	92	21	90	90	CD
cord-017784-4r3fpmlb	92	22	days	day	NNS
cord-017784-4r3fpmlb	92	23	,	,	,
cord-017784-4r3fpmlb	92	24	living	live	VBG
cord-017784-4r3fpmlb	92	25	in	in	IN
cord-017784-4r3fpmlb	92	26	a	a	DT
cord-017784-4r3fpmlb	92	27	residence	residence	NN
cord-017784-4r3fpmlb	92	28	,	,	,
cord-017784-4r3fpmlb	92	29	severe	severe	JJ
cord-017784-4r3fpmlb	92	30	basal	basal	NN
cord-017784-4r3fpmlb	92	31	dependence	dependence	NN
cord-017784-4r3fpmlb	92	32	for	for	IN
cord-017784-4r3fpmlb	92	33	basic	basic	JJ
cord-017784-4r3fpmlb	92	34	daily	daily	JJ
cord-017784-4r3fpmlb	92	35	life	life	NN
cord-017784-4r3fpmlb	92	36	activities	activity	NNS
cord-017784-4r3fpmlb	92	37	,	,	,
cord-017784-4r3fpmlb	92	38	immunodepression	immunodepression	NN
cord-017784-4r3fpmlb	92	39	,	,	,
cord-017784-4r3fpmlb	92	40	or	or	CC
cord-017784-4r3fpmlb	92	41	the	the	DT
cord-017784-4r3fpmlb	92	42	taking	taking	NN
cord-017784-4r3fpmlb	92	43	of	of	IN
cord-017784-4r3fpmlb	92	44	antibiotics	antibiotic	NNS
cord-017784-4r3fpmlb	92	45	in	in	IN
cord-017784-4r3fpmlb	92	46	the	the	DT
cord-017784-4r3fpmlb	92	47	previous	previous	JJ
cord-017784-4r3fpmlb	92	48	6	6	CD
cord-017784-4r3fpmlb	92	49	months	month	NNS
cord-017784-4r3fpmlb	92	50	)	)	-RRB-
cord-017784-4r3fpmlb	93	1	coverage	coverage	NN
cord-017784-4r3fpmlb	93	2	against	against	IN
cord-017784-4r3fpmlb	93	3	MRSA	MRSA	NNP
cord-017784-4r3fpmlb	93	4	should	should	MD
cord-017784-4r3fpmlb	93	5	be	be	VB
cord-017784-4r3fpmlb	93	6	included	include	VBN
cord-017784-4r3fpmlb	93	7	if	if	IN
cord-017784-4r3fpmlb	93	8	the	the	DT
cord-017784-4r3fpmlb	93	9	patient	patient	NN
cord-017784-4r3fpmlb	93	10	presents	present	VBZ
cord-017784-4r3fpmlb	93	11	severe	severe	JJ
cord-017784-4r3fpmlb	93	12	disease	disease	NN
cord-017784-4r3fpmlb	93	13	.	.	.
cord-017784-4r3fpmlb	94	1	Pseudomonas	Pseudomonas	NNP
cord-017784-4r3fpmlb	94	2	aeruginosa	aeruginosa	NN
cord-017784-4r3fpmlb	94	3	is	be	VBZ
cord-017784-4r3fpmlb	94	4	not	not	RB
cord-017784-4r3fpmlb	94	5	a	a	DT
cord-017784-4r3fpmlb	94	6	frequent	frequent	JJ
cord-017784-4r3fpmlb	94	7	pathogen	pathogen	NN
cord-017784-4r3fpmlb	94	8	in	in	IN
cord-017784-4r3fpmlb	94	9	CAP	cap	NN
cord-017784-4r3fpmlb	94	10	;	;	:
cord-017784-4r3fpmlb	94	11	factors	factor	NNS
cord-017784-4r3fpmlb	94	12	increasing	increase	VBG
cord-017784-4r3fpmlb	94	13	the	the	DT
cord-017784-4r3fpmlb	94	14	likelihood	likelihood	NN
cord-017784-4r3fpmlb	94	15	for	for	IN
cord-017784-4r3fpmlb	94	16	Pseudomonas	Pseudomonas	NNP
cord-017784-4r3fpmlb	94	17	infection	infection	NN
cord-017784-4r3fpmlb	94	18	are	be	VBP
cord-017784-4r3fpmlb	94	19	structural	structural	JJ
cord-017784-4r3fpmlb	94	20	lung	lung	NN
cord-017784-4r3fpmlb	94	21	disease	disease	NN
cord-017784-4r3fpmlb	94	22	such	such	JJ
cord-017784-4r3fpmlb	94	23	as	as	IN
cord-017784-4r3fpmlb	94	24	bronchiectasis	bronchiectasis	NN
cord-017784-4r3fpmlb	94	25	or	or	CC
cord-017784-4r3fpmlb	94	26	severe	severe	JJ
cord-017784-4r3fpmlb	94	27	COPD	COPD	NNP
cord-017784-4r3fpmlb	94	28	with	with	IN
cord-017784-4r3fpmlb	94	29	FEV1	FEV1	NNP
cord-017784-4r3fpmlb	94	30	<	<	XX
cord-017784-4r3fpmlb	94	31	35	35	CD
cord-017784-4r3fpmlb	94	32	%	%	NN
cord-017784-4r3fpmlb	94	33	,	,	,
cord-017784-4r3fpmlb	94	34	severe	severe	JJ
cord-017784-4r3fpmlb	94	35	pneumonia	pneumonia	NN
cord-017784-4r3fpmlb	94	36	requiring	require	VBG
cord-017784-4r3fpmlb	94	37	ICU	ICU	NNP
cord-017784-4r3fpmlb	94	38	admission	admission	NN
cord-017784-4r3fpmlb	94	39	,	,	,
cord-017784-4r3fpmlb	94	40	frequent	frequent	JJ
cord-017784-4r3fpmlb	94	41	or	or	CC
cord-017784-4r3fpmlb	94	42	recent	recent	JJ
cord-017784-4r3fpmlb	94	43	use	use	NN
cord-017784-4r3fpmlb	94	44	of	of	IN
cord-017784-4r3fpmlb	94	45	antibiotics	antibiotic	NNS
cord-017784-4r3fpmlb	94	46	,	,	,
cord-017784-4r3fpmlb	94	47	recent	recent	JJ
cord-017784-4r3fpmlb	94	48	hospital	hospital	NN
cord-017784-4r3fpmlb	94	49	admission	admission	NN
cord-017784-4r3fpmlb	94	50	and	and	CC
cord-017784-4r3fpmlb	94	51	steroid	steroid	NN
cord-017784-4r3fpmlb	94	52	use	use	NN
cord-017784-4r3fpmlb	94	53	.	.	.
cord-017784-4r3fpmlb	95	1	Aspiration	Aspiration	NNP
cord-017784-4r3fpmlb	95	2	pneumonia	pneumonia	NN
cord-017784-4r3fpmlb	95	3	refers	refer	VBZ
cord-017784-4r3fpmlb	95	4	to	to	IN
cord-017784-4r3fpmlb	95	5	an	an	DT
cord-017784-4r3fpmlb	95	6	infection	infection	NN
cord-017784-4r3fpmlb	95	7	that	that	WDT
cord-017784-4r3fpmlb	95	8	develops	develop	VBZ
cord-017784-4r3fpmlb	95	9	after	after	IN
cord-017784-4r3fpmlb	95	10	the	the	DT
cord-017784-4r3fpmlb	95	11	entrance	entrance	NN
cord-017784-4r3fpmlb	95	12	of	of	IN
cord-017784-4r3fpmlb	95	13	pathologic	pathologic	JJ
cord-017784-4r3fpmlb	95	14	oropharyngeal	oropharyngeal	JJ
cord-017784-4r3fpmlb	95	15	microbes	microbe	NNS
cord-017784-4r3fpmlb	95	16	into	into	IN
cord-017784-4r3fpmlb	95	17	the	the	DT
cord-017784-4r3fpmlb	95	18	lung	lung	NN
cord-017784-4r3fpmlb	95	19	.	.	.
cord-017784-4r3fpmlb	96	1	Major	major	JJ
cord-017784-4r3fpmlb	96	2	risk	risk	NN
cord-017784-4r3fpmlb	96	3	factors	factor	NNS
cord-017784-4r3fpmlb	96	4	for	for	IN
cord-017784-4r3fpmlb	96	5	aspiration	aspiration	NN
cord-017784-4r3fpmlb	96	6	include	include	VBP
cord-017784-4r3fpmlb	96	7	depressed	depressed	JJ
cord-017784-4r3fpmlb	96	8	consciousness	consciousness	NN
cord-017784-4r3fpmlb	96	9	,	,	,
cord-017784-4r3fpmlb	96	10	compromised	compromise	VBN
cord-017784-4r3fpmlb	96	11	airway	airway	NN
cord-017784-4r3fpmlb	96	12	defenses	defense	NNS
cord-017784-4r3fpmlb	96	13	,	,	,
cord-017784-4r3fpmlb	96	14	dysphagia	dysphagia	NN
cord-017784-4r3fpmlb	96	15	,	,	,
cord-017784-4r3fpmlb	96	16	gastroesophageal	gastroesophageal	JJ
cord-017784-4r3fpmlb	96	17	reflux	reflux	NN
cord-017784-4r3fpmlb	96	18	disease	disease	NN
cord-017784-4r3fpmlb	96	19	,	,	,
cord-017784-4r3fpmlb	96	20	and	and	CC
cord-017784-4r3fpmlb	96	21	recurrent	recurrent	JJ
cord-017784-4r3fpmlb	96	22	vomiting	vomiting	NN
cord-017784-4r3fpmlb	96	23	.	.	.
cord-017784-4r3fpmlb	97	1	Most	Most	JJS
cord-017784-4r3fpmlb	97	2	patients	patient	NNS
cord-017784-4r3fpmlb	97	3	with	with	IN
cord-017784-4r3fpmlb	97	4	communityacquired	communityacquired	JJ
cord-017784-4r3fpmlb	97	5	aspiration	aspiration	NN
cord-017784-4r3fpmlb	97	6	pneumonia	pneumonia	NN
cord-017784-4r3fpmlb	97	7	have	have	VBP
cord-017784-4r3fpmlb	97	8	a	a	DT
cord-017784-4r3fpmlb	97	9	mixed	mixed	JJ
cord-017784-4r3fpmlb	97	10	infection	infection	NN
cord-017784-4r3fpmlb	97	11	with	with	IN
cord-017784-4r3fpmlb	97	12	anaerobic	anaerobic	JJ
cord-017784-4r3fpmlb	97	13	and	and	CC
cord-017784-4r3fpmlb	97	14	aerobic	aerobic	JJ
cord-017784-4r3fpmlb	97	15	bacteria	bacteria	NNS
cord-017784-4r3fpmlb	97	16	,	,	,
cord-017784-4r3fpmlb	97	17	whereas	whereas	IN
cord-017784-4r3fpmlb	97	18	those	those	DT
cord-017784-4r3fpmlb	97	19	with	with	IN
cord-017784-4r3fpmlb	97	20	hospital	hospital	NN
cord-017784-4r3fpmlb	97	21	-	-	HYPH
cord-017784-4r3fpmlb	97	22	acquired	acquire	VBN
cord-017784-4r3fpmlb	97	23	pneumonia	pneumonia	NN
cord-017784-4r3fpmlb	97	24	will	will	MD
cord-017784-4r3fpmlb	97	25	more	more	RBR
cord-017784-4r3fpmlb	97	26	likely	likely	RB
cord-017784-4r3fpmlb	97	27	have	have	VB
cord-017784-4r3fpmlb	97	28	Gram	gram	NN
cord-017784-4r3fpmlb	97	29	-	-	HYPH
cord-017784-4r3fpmlb	97	30	negative	negative	JJ
cord-017784-4r3fpmlb	97	31	infections	infection	NNS
cord-017784-4r3fpmlb	97	32	,	,	,
cord-017784-4r3fpmlb	97	33	including	include	VBG
cord-017784-4r3fpmlb	97	34	Pseudomonas	Pseudomonas	NNP
cord-017784-4r3fpmlb	97	35	aeruginosa	aeruginosa	NN
cord-017784-4r3fpmlb	97	36	[	[	-LRB-
cord-017784-4r3fpmlb	97	37	23	23	CD
cord-017784-4r3fpmlb	97	38	]	]	-RRB-
cord-017784-4r3fpmlb	97	39	.	.	.
cord-017784-4r3fpmlb	98	1	In	in	IN
cord-017784-4r3fpmlb	98	2	regard	regard	NN
cord-017784-4r3fpmlb	98	3	to	to	IN
cord-017784-4r3fpmlb	98	4	viral	viral	JJ
cord-017784-4r3fpmlb	98	5	etiology	etiology	NN
cord-017784-4r3fpmlb	98	6	,	,	,
cord-017784-4r3fpmlb	98	7	the	the	DT
cord-017784-4r3fpmlb	98	8	influenza	influenza	NN
cord-017784-4r3fpmlb	98	9	virus	virus	NN
cord-017784-4r3fpmlb	98	10	and	and	CC
cord-017784-4r3fpmlb	98	11	respiratory	respiratory	JJ
cord-017784-4r3fpmlb	98	12	syncytial	syncytial	JJ
cord-017784-4r3fpmlb	98	13	virus	virus	NN
cord-017784-4r3fpmlb	98	14	are	be	VBP
cord-017784-4r3fpmlb	98	15	most	most	RBS
cord-017784-4r3fpmlb	98	16	important	important	JJ
cord-017784-4r3fpmlb	98	17	cause	cause	NN
cord-017784-4r3fpmlb	98	18	of	of	IN
cord-017784-4r3fpmlb	98	19	pneumonia	pneumonia	NN
cord-017784-4r3fpmlb	98	20	in	in	IN
cord-017784-4r3fpmlb	98	21	the	the	DT
cord-017784-4r3fpmlb	98	22	elderly	elderly	JJ
cord-017784-4r3fpmlb	98	23	,	,	,
cord-017784-4r3fpmlb	98	24	often	often	RB
cord-017784-4r3fpmlb	98	25	within	within	IN
cord-017784-4r3fpmlb	98	26	the	the	DT
cord-017784-4r3fpmlb	98	27	context	context	NN
cord-017784-4r3fpmlb	98	28	of	of	IN
cord-017784-4r3fpmlb	98	29	epidemic	epidemic	NN
cord-017784-4r3fpmlb	98	30	outbreaks	outbreak	NNS
cord-017784-4r3fpmlb	98	31	and	and	CC
cord-017784-4r3fpmlb	98	32	may	may	MD
cord-017784-4r3fpmlb	98	33	cause	cause	VB
cord-017784-4r3fpmlb	98	34	both	both	DT
cord-017784-4r3fpmlb	98	35	viral	viral	JJ
cord-017784-4r3fpmlb	98	36	primary	primary	JJ
cord-017784-4r3fpmlb	98	37	pneumonias	pneumonia	NNS
cord-017784-4r3fpmlb	98	38	such	such	JJ
cord-017784-4r3fpmlb	98	39	as	as	IN
cord-017784-4r3fpmlb	98	40	bacterial	bacterial	JJ
cord-017784-4r3fpmlb	98	41	superinfection	superinfection	NN
cord-017784-4r3fpmlb	98	42	by	by	IN
cord-017784-4r3fpmlb	98	43	S.	S.	NNP
cord-017784-4r3fpmlb	98	44	pneumoniae	pneumoniae	NN
cord-017784-4r3fpmlb	98	45	,	,	,
cord-017784-4r3fpmlb	98	46	S.	S.	NNP
cord-017784-4r3fpmlb	98	47	aureus	aureus	NN
cord-017784-4r3fpmlb	98	48	,	,	,
cord-017784-4r3fpmlb	98	49	and	and	CC
cord-017784-4r3fpmlb	98	50	Haemophilus	haemophilus	JJ
cord-017784-4r3fpmlb	98	51	influenzae	influenzae	NN
cord-017784-4r3fpmlb	98	52	.	.	.
cord-017784-4r3fpmlb	99	1	(	(	-LRB-
cord-017784-4r3fpmlb	99	2	Table	table	NN
cord-017784-4r3fpmlb	99	3	5	5	CD
cord-017784-4r3fpmlb	99	4	.	.	.
cord-017784-4r3fpmlb	99	5	 	 	_SP
cord-017784-4r3fpmlb	100	1	Antimicrobials	antimicrobial	NNS
cord-017784-4r3fpmlb	100	2	are	be	VBP
cord-017784-4r3fpmlb	100	3	the	the	DT
cord-017784-4r3fpmlb	100	4	cornerstone	cornerstone	NN
cord-017784-4r3fpmlb	100	5	of	of	IN
cord-017784-4r3fpmlb	100	6	therapy	therapy	NN
cord-017784-4r3fpmlb	100	7	for	for	IN
cord-017784-4r3fpmlb	100	8	CAP	cap	NN
cord-017784-4r3fpmlb	100	9	in	in	IN
cord-017784-4r3fpmlb	100	10	any	any	DT
cord-017784-4r3fpmlb	100	11	population	population	NN
cord-017784-4r3fpmlb	100	12	,	,	,
cord-017784-4r3fpmlb	100	13	but	but	CC
cord-017784-4r3fpmlb	100	14	limited	limited	JJ
cord-017784-4r3fpmlb	100	15	data	datum	NNS
cord-017784-4r3fpmlb	100	16	are	be	VBP
cord-017784-4r3fpmlb	100	17	available	available	JJ
cord-017784-4r3fpmlb	100	18	regarding	regard	VBG
cord-017784-4r3fpmlb	100	19	the	the	DT
cord-017784-4r3fpmlb	100	20	specific	specific	JJ
cord-017784-4r3fpmlb	100	21	treatments	treatment	NNS
cord-017784-4r3fpmlb	100	22	for	for	IN
cord-017784-4r3fpmlb	100	23	elderly	elderly	JJ
cord-017784-4r3fpmlb	100	24	patients	patient	NNS
cord-017784-4r3fpmlb	100	25	.	.	.
cord-017784-4r3fpmlb	101	1	The	the	DT
cord-017784-4r3fpmlb	101	2	only	only	JJ
cord-017784-4r3fpmlb	101	3	guidelines	guideline	NNS
cord-017784-4r3fpmlb	101	4	for	for	IN
cord-017784-4r3fpmlb	101	5	the	the	DT
cord-017784-4r3fpmlb	101	6	management	management	NN
cord-017784-4r3fpmlb	101	7	of	of	IN
cord-017784-4r3fpmlb	101	8	community	community	NN
cord-017784-4r3fpmlb	101	9	-	-	HYPH
cord-017784-4r3fpmlb	101	10	acquired	acquire	VBN
cord-017784-4r3fpmlb	101	11	pneumonia	pneumonia	NN
cord-017784-4r3fpmlb	101	12	in	in	IN
cord-017784-4r3fpmlb	101	13	the	the	DT
cord-017784-4r3fpmlb	101	14	elderly	elderly	JJ
cord-017784-4r3fpmlb	101	15	patient	patient	NN
cord-017784-4r3fpmlb	101	16	are	be	VBP
cord-017784-4r3fpmlb	101	17	published	publish	VBN
cord-017784-4r3fpmlb	101	18	in	in	IN
cord-017784-4r3fpmlb	101	19	the	the	DT
cord-017784-4r3fpmlb	101	20	year	year	NN
cord-017784-4r3fpmlb	101	21	2014	2014	CD
cord-017784-4r3fpmlb	101	22	in	in	IN
cord-017784-4r3fpmlb	101	23	Spanish	Spanish	NNP
cord-017784-4r3fpmlb	101	24	[	[	-LRB-
cord-017784-4r3fpmlb	101	25	24	24	CD
cord-017784-4r3fpmlb	101	26	]	]	-RRB-
cord-017784-4r3fpmlb	101	27	.	.	.
cord-017784-4r3fpmlb	102	1	Initial	initial	JJ
cord-017784-4r3fpmlb	102	2	antibiotic	antibiotic	JJ
cord-017784-4r3fpmlb	102	3	selection	selection	NN
cord-017784-4r3fpmlb	102	4	for	for	IN
cord-017784-4r3fpmlb	102	5	CAP	CAP	NNP
cord-017784-4r3fpmlb	102	6	is	be	VBZ
cord-017784-4r3fpmlb	102	7	often	often	RB
cord-017784-4r3fpmlb	102	8	empirical	empirical	JJ
cord-017784-4r3fpmlb	102	9	,	,	,
cord-017784-4r3fpmlb	102	10	as	as	IN
cord-017784-4r3fpmlb	102	11	the	the	DT
cord-017784-4r3fpmlb	102	12	causative	causative	JJ
cord-017784-4r3fpmlb	102	13	pathogen	pathogen	NN
cord-017784-4r3fpmlb	102	14	can	can	MD
cord-017784-4r3fpmlb	102	15	not	not	RB
cord-017784-4r3fpmlb	102	16	be	be	VB
cord-017784-4r3fpmlb	102	17	predicted	predict	VBN
cord-017784-4r3fpmlb	102	18	from	from	IN
cord-017784-4r3fpmlb	102	19	clinical	clinical	JJ
cord-017784-4r3fpmlb	102	20	laboratory	laboratory	NN
cord-017784-4r3fpmlb	102	21	or	or	CC
cord-017784-4r3fpmlb	102	22	radiological	radiological	JJ
cord-017784-4r3fpmlb	102	23	findings	finding	NNS
cord-017784-4r3fpmlb	102	24	and	and	CC
cord-017784-4r3fpmlb	102	25	therapy	therapy	NN
cord-017784-4r3fpmlb	102	26	must	must	MD
cord-017784-4r3fpmlb	102	27	be	be	VB
cord-017784-4r3fpmlb	102	28	started	start	VBN
cord-017784-4r3fpmlb	102	29	swiftly	swiftly	RB
cord-017784-4r3fpmlb	102	30	as	as	RB
cord-017784-4r3fpmlb	102	31	rapid	rapid	JJ
cord-017784-4r3fpmlb	102	32	antibiotic	antibiotic	JJ
cord-017784-4r3fpmlb	102	33	delivery	delivery	NN
cord-017784-4r3fpmlb	102	34	is	be	VBZ
cord-017784-4r3fpmlb	102	35	associated	associate	VBN
cord-017784-4r3fpmlb	102	36	with	with	IN
cord-017784-4r3fpmlb	102	37	a	a	DT
cord-017784-4r3fpmlb	102	38	better	well	JJR
cord-017784-4r3fpmlb	102	39	outcome	outcome	NN
cord-017784-4r3fpmlb	102	40	[	[	-LRB-
cord-017784-4r3fpmlb	102	41	25	25	CD
cord-017784-4r3fpmlb	102	42	]	]	-RRB-
cord-017784-4r3fpmlb	102	43	.	.	.
cord-017784-4r3fpmlb	103	1	Empirical	empirical	JJ
cord-017784-4r3fpmlb	103	2	antimicrobial	antimicrobial	JJ
cord-017784-4r3fpmlb	103	3	therapy	therapy	NN
cord-017784-4r3fpmlb	103	4	must	must	MD
cord-017784-4r3fpmlb	103	5	include	include	VB
cord-017784-4r3fpmlb	103	6	coverage	coverage	NN
cord-017784-4r3fpmlb	103	7	for	for	IN
cord-017784-4r3fpmlb	103	8	the	the	DT
cord-017784-4r3fpmlb	103	9	most	most	RBS
cord-017784-4r3fpmlb	103	10	prevalent	prevalent	JJ
cord-017784-4r3fpmlb	103	11	pathogens	pathogen	NNS
cord-017784-4r3fpmlb	103	12	and	and	CC
cord-017784-4r3fpmlb	103	13	should	should	MD
cord-017784-4r3fpmlb	103	14	be	be	VB
cord-017784-4r3fpmlb	103	15	based	base	VBN
cord-017784-4r3fpmlb	103	16	on	on	IN
cord-017784-4r3fpmlb	103	17	several	several	JJ
cord-017784-4r3fpmlb	103	18	aspects	aspect	NNS
cord-017784-4r3fpmlb	103	19	such	such	JJ
cord-017784-4r3fpmlb	103	20	as	as	IN
cord-017784-4r3fpmlb	103	21	the	the	DT
cord-017784-4r3fpmlb	103	22	severity	severity	NN
cord-017784-4r3fpmlb	103	23	of	of	IN
cord-017784-4r3fpmlb	103	24	diseases	disease	NNS
cord-017784-4r3fpmlb	103	25	,	,	,
cord-017784-4r3fpmlb	103	26	local	local	JJ
cord-017784-4r3fpmlb	103	27	patterns	pattern	NNS
cord-017784-4r3fpmlb	103	28	of	of	IN
cord-017784-4r3fpmlb	103	29	antimicrobial	antimicrobial	JJ
cord-017784-4r3fpmlb	103	30	resistances	resistance	NNS
cord-017784-4r3fpmlb	103	31	,	,	,
cord-017784-4r3fpmlb	103	32	multi	multi	JJ
cord-017784-4r3fpmlb	103	33	-	-	JJ
cord-017784-4r3fpmlb	103	34	drug	drug	JJ
cord-017784-4r3fpmlb	103	35	-	-	HYPH
cord-017784-4r3fpmlb	103	36	resistant	resistant	JJ
cord-017784-4r3fpmlb	103	37	risk	risk	NN
cord-017784-4r3fpmlb	103	38	factors	factor	NNS
cord-017784-4r3fpmlb	103	39	,	,	,
cord-017784-4r3fpmlb	103	40	and	and	CC
cord-017784-4r3fpmlb	103	41	drug	drug	NN
cord-017784-4r3fpmlb	103	42	allergies	allergy	NNS
cord-017784-4r3fpmlb	103	43	.	.	.
cord-017784-4r3fpmlb	104	1	International	international	JJ
cord-017784-4r3fpmlb	104	2	guidelines	guideline	NNS
cord-017784-4r3fpmlb	104	3	agree	agree	VBP
cord-017784-4r3fpmlb	104	4	that	that	IN
cord-017784-4r3fpmlb	104	5	patients	patient	NNS
cord-017784-4r3fpmlb	104	6	hospitalized	hospitalize	VBN
cord-017784-4r3fpmlb	104	7	with	with	IN
cord-017784-4r3fpmlb	104	8	non	non	JJ
cord-017784-4r3fpmlb	104	9	-	-	JJ
cord-017784-4r3fpmlb	104	10	severe	severe	JJ
cord-017784-4r3fpmlb	104	11	CAP	cap	NN
cord-017784-4r3fpmlb	104	12	should	should	MD
cord-017784-4r3fpmlb	104	13	be	be	VB
cord-017784-4r3fpmlb	104	14	started	start	VBN
cord-017784-4r3fpmlb	104	15	on	on	IN
cord-017784-4r3fpmlb	104	16	empirical	empirical	JJ
cord-017784-4r3fpmlb	104	17	combination	combination	NN
cord-017784-4r3fpmlb	104	18	therapy	therapy	NN
cord-017784-4r3fpmlb	104	19	using	use	VBG
cord-017784-4r3fpmlb	104	20	a	a	DT
cord-017784-4r3fpmlb	104	21	β	β	NN
cord-017784-4r3fpmlb	104	22	-	-	HYPH
cord-017784-4r3fpmlb	104	23	lactam	lactam	NNP
cord-017784-4r3fpmlb	104	24	plus	plus	CC
cord-017784-4r3fpmlb	104	25	a	a	DT
cord-017784-4r3fpmlb	104	26	macrolide	macrolide	NN
cord-017784-4r3fpmlb	104	27	or	or	CC
cord-017784-4r3fpmlb	104	28	a	a	DT
cord-017784-4r3fpmlb	104	29	respiratory	respiratory	JJ
cord-017784-4r3fpmlb	104	30	fluoroquinolone	fluoroquinolone	NN
cord-017784-4r3fpmlb	104	31	alone	alone	RB
cord-017784-4r3fpmlb	104	32	(	(	-LRB-
cord-017784-4r3fpmlb	104	33	levofloxacin	levofloxacin	NNP
cord-017784-4r3fpmlb	104	34	,	,	,
cord-017784-4r3fpmlb	104	35	moxifloxacin	moxifloxacin	NNS
cord-017784-4r3fpmlb	104	36	,	,	,
cord-017784-4r3fpmlb	104	37	and	and	CC
cord-017784-4r3fpmlb	104	38	gatifloxacin	gatifloxacin	NNP
cord-017784-4r3fpmlb	104	39	)	)	-RRB-
cord-017784-4r3fpmlb	104	40	.	.	.
cord-017784-4r3fpmlb	105	1	The	the	DT
cord-017784-4r3fpmlb	105	2	respiratory	respiratory	JJ
cord-017784-4r3fpmlb	105	3	quinolones	quinolone	NNS
cord-017784-4r3fpmlb	105	4	are	be	VBP
cord-017784-4r3fpmlb	105	5	quinolones	quinolone	NNS
cord-017784-4r3fpmlb	105	6	that	that	WDT
cord-017784-4r3fpmlb	105	7	are	be	VBP
cord-017784-4r3fpmlb	105	8	highly	highly	RB
cord-017784-4r3fpmlb	105	9	active	active	JJ
cord-017784-4r3fpmlb	105	10	against	against	IN
cord-017784-4r3fpmlb	105	11	both	both	CC
cord-017784-4r3fpmlb	105	12	the	the	DT
cord-017784-4r3fpmlb	105	13	typical	typical	JJ
cord-017784-4r3fpmlb	105	14	and	and	CC
cord-017784-4r3fpmlb	105	15	atypical	atypical	JJ
cord-017784-4r3fpmlb	105	16	respiratory	respiratory	JJ
cord-017784-4r3fpmlb	105	17	pathogens	pathogen	NNS
cord-017784-4r3fpmlb	105	18	causing	cause	VBG
cord-017784-4r3fpmlb	105	19	CAP	cap	NN
cord-017784-4r3fpmlb	105	20	.	.	.
cord-017784-4r3fpmlb	106	1	Because	because	IN
cord-017784-4r3fpmlb	106	2	ciprofloxacin	ciprofloxacin	NN
cord-017784-4r3fpmlb	106	3	is	be	VBZ
cord-017784-4r3fpmlb	106	4	relatively	relatively	RB
cord-017784-4r3fpmlb	106	5	inactive	inactive	JJ
cord-017784-4r3fpmlb	106	6	against	against	IN
cord-017784-4r3fpmlb	106	7	Streptococcus	streptococcus	NN
cord-017784-4r3fpmlb	106	8	pneumoniae	pneumoniae	NN
cord-017784-4r3fpmlb	106	9	,	,	,
cord-017784-4r3fpmlb	106	10	even	even	RB
cord-017784-4r3fpmlb	106	11	though	though	IN
cord-017784-4r3fpmlb	106	12	it	-PRON-	PRP
cord-017784-4r3fpmlb	106	13	is	be	VBZ
cord-017784-4r3fpmlb	106	14	active	active	JJ
cord-017784-4r3fpmlb	106	15	against	against	IN
cord-017784-4r3fpmlb	106	16	the	the	DT
cord-017784-4r3fpmlb	106	17	atypical	atypical	JJ
cord-017784-4r3fpmlb	106	18	pathogens	pathogen	NNS
cord-017784-4r3fpmlb	106	19	,	,	,
cord-017784-4r3fpmlb	106	20	it	-PRON-	PRP
cord-017784-4r3fpmlb	106	21	is	be	VBZ
cord-017784-4r3fpmlb	106	22	not	not	RB
cord-017784-4r3fpmlb	106	23	termed	term	VBN
cord-017784-4r3fpmlb	106	24	a	a	DT
cord-017784-4r3fpmlb	106	25	"	"	``
cord-017784-4r3fpmlb	106	26	respiratory	respiratory	JJ
cord-017784-4r3fpmlb	106	27	quinolone	quinolone	NN
cord-017784-4r3fpmlb	106	28	.	.	.
cord-017784-4r3fpmlb	106	29	"	"	''
cord-017784-4r3fpmlb	107	1	In	in	IN
cord-017784-4r3fpmlb	107	2	patients	patient	NNS
cord-017784-4r3fpmlb	107	3	with	with	IN
cord-017784-4r3fpmlb	107	4	severe	severe	JJ
cord-017784-4r3fpmlb	107	5	community	community	NN
cord-017784-4r3fpmlb	107	6	-	-	HYPH
cord-017784-4r3fpmlb	107	7	acquired	acquire	VBN
cord-017784-4r3fpmlb	107	8	pneumonia	pneumonia	NN
cord-017784-4r3fpmlb	107	9	(	(	-LRB-
cord-017784-4r3fpmlb	107	10	admission	admission	NN
cord-017784-4r3fpmlb	107	11	in	in	IN
cord-017784-4r3fpmlb	107	12	ICU	ICU	NNP
cord-017784-4r3fpmlb	107	13	or	or	CC
cord-017784-4r3fpmlb	107	14	intermediate	intermediate	JJ
cord-017784-4r3fpmlb	107	15	care	care	NN
cord-017784-4r3fpmlb	107	16	)	)	-RRB-
cord-017784-4r3fpmlb	107	17	,	,	,
cord-017784-4r3fpmlb	107	18	the	the	DT
cord-017784-4r3fpmlb	107	19	guidelines	guideline	NNS
cord-017784-4r3fpmlb	107	20	recommend	recommend	VBP
cord-017784-4r3fpmlb	107	21	a	a	DT
cord-017784-4r3fpmlb	107	22	minimum	minimum	NN
cord-017784-4r3fpmlb	107	23	of	of	IN
cord-017784-4r3fpmlb	107	24	a	a	DT
cord-017784-4r3fpmlb	107	25	β	β	NN
cord-017784-4r3fpmlb	107	26	-	-	HYPH
cord-017784-4r3fpmlb	107	27	lactam	lactam	NNS
cord-017784-4r3fpmlb	107	28	plus	plus	CC
cord-017784-4r3fpmlb	107	29	either	either	CC
cord-017784-4r3fpmlb	107	30	a	a	DT
cord-017784-4r3fpmlb	107	31	macrolide	macrolide	NN
cord-017784-4r3fpmlb	107	32	or	or	CC
cord-017784-4r3fpmlb	107	33	a	a	DT
cord-017784-4r3fpmlb	107	34	quinolone	quinolone	NN
cord-017784-4r3fpmlb	107	35	.	.	.
cord-017784-4r3fpmlb	108	1	The	the	DT
cord-017784-4r3fpmlb	108	2	combination	combination	NN
cord-017784-4r3fpmlb	108	3	treatment	treatment	NN
cord-017784-4r3fpmlb	108	4	offers	offer	VBZ
cord-017784-4r3fpmlb	108	5	an	an	DT
cord-017784-4r3fpmlb	108	6	advantage	advantage	NN
cord-017784-4r3fpmlb	108	7	over	over	IN
cord-017784-4r3fpmlb	108	8	monotherapy	monotherapy	NN
cord-017784-4r3fpmlb	108	9	by	by	IN
cord-017784-4r3fpmlb	108	10	expanding	expand	VBG
cord-017784-4r3fpmlb	108	11	the	the	DT
cord-017784-4r3fpmlb	108	12	antimicrobial	antimicrobial	JJ
cord-017784-4r3fpmlb	108	13	coverage	coverage	NN
cord-017784-4r3fpmlb	108	14	and	and	CC
cord-017784-4r3fpmlb	108	15	probably	probably	RB
cord-017784-4r3fpmlb	108	16	by	by	IN
cord-017784-4r3fpmlb	108	17	immunomodulation	immunomodulation	NNP
cord-017784-4r3fpmlb	108	18	(	(	-LRB-
cord-017784-4r3fpmlb	108	19	macrolides	macrolide	NNS
cord-017784-4r3fpmlb	108	20	,	,	,
cord-017784-4r3fpmlb	108	21	quinolones	quinolones	NNP
cord-017784-4r3fpmlb	108	22	)	)	-RRB-
cord-017784-4r3fpmlb	108	23	.	.	.
cord-017784-4r3fpmlb	109	1	In	in	IN
cord-017784-4r3fpmlb	109	2	severe	severe	JJ
cord-017784-4r3fpmlb	109	3	patients	patient	NNS
cord-017784-4r3fpmlb	109	4	with	with	IN
cord-017784-4r3fpmlb	109	5	risk	risk	NN
cord-017784-4r3fpmlb	109	6	factors	factor	NNS
cord-017784-4r3fpmlb	109	7	for	for	IN
cord-017784-4r3fpmlb	109	8	MRSA	MRSA	NNP
cord-017784-4r3fpmlb	109	9	vancomycin	vancomycin	NNS
cord-017784-4r3fpmlb	109	10	or	or	CC
cord-017784-4r3fpmlb	109	11	linezolid	linezolid	NN
cord-017784-4r3fpmlb	109	12	should	should	MD
cord-017784-4r3fpmlb	109	13	be	be	VB
cord-017784-4r3fpmlb	109	14	added	add	VBN
cord-017784-4r3fpmlb	109	15	.	.	.
cord-017784-4r3fpmlb	110	1	CAP	cap	NN
cord-017784-4r3fpmlb	110	2	patients	patient	NNS
cord-017784-4r3fpmlb	110	3	with	with	IN
cord-017784-4r3fpmlb	110	4	risk	risk	NN
cord-017784-4r3fpmlb	110	5	factors	factor	NNS
cord-017784-4r3fpmlb	110	6	for	for	IN
cord-017784-4r3fpmlb	110	7	P.	p.	NN
cord-017784-4r3fpmlb	110	8	aeruginosa	aeruginosa	NN
cord-017784-4r3fpmlb	110	9	should	should	MD
cord-017784-4r3fpmlb	110	10	receive	receive	VB
cord-017784-4r3fpmlb	110	11	empirical	empirical	JJ
cord-017784-4r3fpmlb	110	12	combination	combination	NN
cord-017784-4r3fpmlb	110	13	therapy	therapy	NN
cord-017784-4r3fpmlb	110	14	as	as	IN
cord-017784-4r3fpmlb	110	15	an	an	DT
cord-017784-4r3fpmlb	110	16	antipneumococcal	antipneumococcal	JJ
cord-017784-4r3fpmlb	110	17	anti	anti	JJ
cord-017784-4r3fpmlb	110	18	-	-	JJ
cord-017784-4r3fpmlb	110	19	pseudomonal	pseudomonal	JJ
cord-017784-4r3fpmlb	110	20	β	β	NN
cord-017784-4r3fpmlb	110	21	-	-	HYPH
cord-017784-4r3fpmlb	110	22	lactam	lactam	NNP
cord-017784-4r3fpmlb	110	23	plus	plus	CC
cord-017784-4r3fpmlb	110	24	either	either	CC
cord-017784-4r3fpmlb	110	25	ciprofloxacin	ciprofloxacin	NN
cord-017784-4r3fpmlb	110	26	or	or	CC
cord-017784-4r3fpmlb	110	27	high	high	JJ
cord-017784-4r3fpmlb	110	28	-	-	HYPH
cord-017784-4r3fpmlb	110	29	dose	dose	NN
cord-017784-4r3fpmlb	110	30	levofloxacin	levofloxacin	NNS
cord-017784-4r3fpmlb	110	31	or	or	CC
cord-017784-4r3fpmlb	110	32	the	the	DT
cord-017784-4r3fpmlb	110	33	above	above	JJ
cord-017784-4r3fpmlb	110	34	β	β	NN
cord-017784-4r3fpmlb	110	35	-	-	HYPH
cord-017784-4r3fpmlb	110	36	lactam	lactam	NNP
cord-017784-4r3fpmlb	110	37	plus	plus	CC
cord-017784-4r3fpmlb	110	38	an	an	DT
cord-017784-4r3fpmlb	110	39	aminoglycoside	aminoglycoside	NN
cord-017784-4r3fpmlb	110	40	and	and	CC
cord-017784-4r3fpmlb	110	41	azithromycin	azithromycin	NN
cord-017784-4r3fpmlb	110	42	is	be	VBZ
cord-017784-4r3fpmlb	110	43	an	an	DT
cord-017784-4r3fpmlb	110	44	appropriate	appropriate	JJ
cord-017784-4r3fpmlb	110	45	regimen	regimen	NN
cord-017784-4r3fpmlb	110	46	.	.	.
cord-017784-4r3fpmlb	111	1	In	in	IN
cord-017784-4r3fpmlb	111	2	patients	patient	NNS
cord-017784-4r3fpmlb	111	3	with	with	IN
cord-017784-4r3fpmlb	111	4	risk	risk	NN
cord-017784-4r3fpmlb	111	5	factors	factor	NNS
cord-017784-4r3fpmlb	111	6	of	of	IN
cord-017784-4r3fpmlb	111	7	aspiration	aspiration	NN
cord-017784-4r3fpmlb	111	8	,	,	,
cord-017784-4r3fpmlb	111	9	an	an	DT
cord-017784-4r3fpmlb	111	10	antibiotic	antibiotic	NN
cord-017784-4r3fpmlb	111	11	should	should	MD
cord-017784-4r3fpmlb	111	12	be	be	VB
cord-017784-4r3fpmlb	111	13	used	use	VBN
cord-017784-4r3fpmlb	111	14	which	which	WDT
cord-017784-4r3fpmlb	111	15	should	should	MD
cord-017784-4r3fpmlb	111	16	also	also	RB
cord-017784-4r3fpmlb	111	17	cover	cover	VB
cord-017784-4r3fpmlb	111	18	S.	S.	NNP
cord-017784-4r3fpmlb	111	19	pneumoniae	pneumoniae	NN
cord-017784-4r3fpmlb	111	20	and	and	CC
cord-017784-4r3fpmlb	111	21	be	be	VB
cord-017784-4r3fpmlb	111	22	effective	effective	JJ
cord-017784-4r3fpmlb	111	23	against	against	IN
cord-017784-4r3fpmlb	111	24	anaerobes	anaerobe	NNS
cord-017784-4r3fpmlb	111	25	and	and	CC
cord-017784-4r3fpmlb	111	26	Enterobacteriaceae	Enterobacteriaceae	NNP
cord-017784-4r3fpmlb	111	27	since	since	IN
cord-017784-4r3fpmlb	111	28	these	these	DT
cord-017784-4r3fpmlb	111	29	may	may	MD
cord-017784-4r3fpmlb	111	30	be	be	VB
cord-017784-4r3fpmlb	111	31	the	the	DT
cord-017784-4r3fpmlb	111	32	causal	causal	JJ
cord-017784-4r3fpmlb	111	33	microorganisms	microorganism	NNS
cord-017784-4r3fpmlb	111	34	involved	involve	VBN
cord-017784-4r3fpmlb	111	35	.	.	.
cord-017784-4r3fpmlb	112	1	In	in	IN
cord-017784-4r3fpmlb	112	2	most	most	JJS
cord-017784-4r3fpmlb	112	3	guidelines	guideline	NNS
cord-017784-4r3fpmlb	112	4	,	,	,
cord-017784-4r3fpmlb	112	5	β	β	NN
cord-017784-4r3fpmlb	112	6	-	-	HYPH
cord-017784-4r3fpmlb	112	7	lactam	lactam	NNP
cord-017784-4r3fpmlb	112	8	/	/	SYM
cord-017784-4r3fpmlb	112	9	β	β	NN
cord-017784-4r3fpmlb	112	10	-	-	HYPH
cord-017784-4r3fpmlb	112	11	lactamase	lactamase	NNP
cord-017784-4r3fpmlb	112	12	inhibitors	inhibitor	NNS
cord-017784-4r3fpmlb	112	13	(	(	-LRB-
cord-017784-4r3fpmlb	112	14	amoxicillin	amoxicillin	NNP
cord-017784-4r3fpmlb	112	15	-	-	HYPH
cord-017784-4r3fpmlb	112	16	clavulanate	clavulanate	NNP
cord-017784-4r3fpmlb	112	17	,	,	,
cord-017784-4r3fpmlb	112	18	ampicillin	ampicillin	NN
cord-017784-4r3fpmlb	112	19	/	/	SYM
cord-017784-4r3fpmlb	112	20	sulbactam	sulbactam	NNP
cord-017784-4r3fpmlb	112	21	/	/	SYM
cord-017784-4r3fpmlb	112	22	piperacillin	piperacillin	NNP
cord-017784-4r3fpmlb	112	23	/	/	SYM
cord-017784-4r3fpmlb	112	24	tazobactam	tazobactam	NNP
cord-017784-4r3fpmlb	112	25	)	)	-RRB-
cord-017784-4r3fpmlb	112	26	are	be	VBP
cord-017784-4r3fpmlb	112	27	considered	consider	VBN
cord-017784-4r3fpmlb	112	28	to	to	TO
cord-017784-4r3fpmlb	112	29	be	be	VB
cord-017784-4r3fpmlb	112	30	the	the	DT
cord-017784-4r3fpmlb	112	31	antibiotics	antibiotic	NNS
cord-017784-4r3fpmlb	112	32	of	of	IN
cord-017784-4r3fpmlb	112	33	choice	choice	NN
cord-017784-4r3fpmlb	112	34	.	.	.
cord-017784-4r3fpmlb	113	1	Ceftriaxone	Ceftriaxone	NNP
cord-017784-4r3fpmlb	113	2	plus	plus	CC
cord-017784-4r3fpmlb	113	3	clindamycin	clindamycin	NN
cord-017784-4r3fpmlb	113	4	or	or	CC
cord-017784-4r3fpmlb	113	5	metronidazole	metronidazole	NN
cord-017784-4r3fpmlb	113	6	and	and	CC
cord-017784-4r3fpmlb	113	7	respiratory	respiratory	JJ
cord-017784-4r3fpmlb	113	8	fluoroquinolone	fluoroquinolone	NN
cord-017784-4r3fpmlb	113	9	are	be	VBP
cord-017784-4r3fpmlb	113	10	the	the	DT
cord-017784-4r3fpmlb	113	11	alternative	alternative	NN
cord-017784-4r3fpmlb	113	12	.	.	.
cord-017784-4r3fpmlb	114	1	For	for	IN
cord-017784-4r3fpmlb	114	2	patients	patient	NNS
cord-017784-4r3fpmlb	114	3	at	at	IN
cord-017784-4r3fpmlb	114	4	the	the	DT
cord-017784-4r3fpmlb	114	5	increasing	increase	VBG
cord-017784-4r3fpmlb	114	6	rise	rise	NN
cord-017784-4r3fpmlb	114	7	of	of	IN
cord-017784-4r3fpmlb	114	8	resistances	resistance	NNS
cord-017784-4r3fpmlb	114	9	of	of	IN
cord-017784-4r3fpmlb	114	10	Enterobacteriaceae	Enterobacteriaceae	NNP
cord-017784-4r3fpmlb	114	11	ertapenem	ertapenem	NN
cord-017784-4r3fpmlb	114	12	this	this	DT
cord-017784-4r3fpmlb	114	13	therapeutic	therapeutic	JJ
cord-017784-4r3fpmlb	114	14	option	option	NN
cord-017784-4r3fpmlb	114	15	is	be	VBZ
cord-017784-4r3fpmlb	114	16	valid	valid	JJ
cord-017784-4r3fpmlb	114	17	mainly	mainly	RB
cord-017784-4r3fpmlb	114	18	for	for	IN
cord-017784-4r3fpmlb	114	19	its	-PRON-	PRP$
cord-017784-4r3fpmlb	114	20	sensitivity	sensitivity	NN
cord-017784-4r3fpmlb	114	21	versus	versus	IN
cord-017784-4r3fpmlb	114	22	anaerobes	anaerobe	NNS
cord-017784-4r3fpmlb	114	23	,	,	,
cord-017784-4r3fpmlb	114	24	S.	S.	NNP
cord-017784-4r3fpmlb	114	25	pneumoniae	pneumoniae	NN
cord-017784-4r3fpmlb	114	26	,	,	,
cord-017784-4r3fpmlb	114	27	and	and	CC
cord-017784-4r3fpmlb	114	28	all	all	PDT
cord-017784-4r3fpmlb	114	29	the	the	DT
cord-017784-4r3fpmlb	114	30	Enterobacteriaceae	Enterobacteriaceae	NNP
cord-017784-4r3fpmlb	114	31	,	,	,
cord-017784-4r3fpmlb	114	32	including	include	VBG
cord-017784-4r3fpmlb	114	33	extended	extend	VBN
cord-017784-4r3fpmlb	114	34	-	-	HYPH
cord-017784-4r3fpmlb	114	35	spectrum	spectrum	NN
cord-017784-4r3fpmlb	114	36	β	β	NN
cord-017784-4r3fpmlb	114	37	-	-	HYPH
cord-017784-4r3fpmlb	114	38	Lactamase	Lactamase	NNP
cord-017784-4r3fpmlb	114	39	-	-	HYPH
cord-017784-4r3fpmlb	114	40	producing	produce	VBG
cord-017784-4r3fpmlb	114	41	(	(	-LRB-
cord-017784-4r3fpmlb	114	42	ESBL	ESBL	NNP
cord-017784-4r3fpmlb	114	43	)	)	-RRB-
cord-017784-4r3fpmlb	114	44	.	.	.
cord-017784-4r3fpmlb	115	1	Antibiotic	antibiotic	JJ
cord-017784-4r3fpmlb	115	2	agents	agent	NNS
cord-017784-4r3fpmlb	115	3	with	with	IN
cord-017784-4r3fpmlb	115	4	specific	specific	JJ
cord-017784-4r3fpmlb	115	5	anaerobic	anaerobic	JJ
cord-017784-4r3fpmlb	115	6	activity	activity	NN
cord-017784-4r3fpmlb	115	7	(	(	-LRB-
cord-017784-4r3fpmlb	115	8	metronidazole	metronidazole	NN
cord-017784-4r3fpmlb	115	9	or	or	CC
cord-017784-4r3fpmlb	115	10	clindamycin	clindamycin	NN
cord-017784-4r3fpmlb	115	11	)	)	-RRB-
cord-017784-4r3fpmlb	115	12	are	be	VBP
cord-017784-4r3fpmlb	115	13	not	not	RB
cord-017784-4r3fpmlb	115	14	routinely	routinely	RB
cord-017784-4r3fpmlb	115	15	warranted	warrant	VBN
cord-017784-4r3fpmlb	115	16	and	and	CC
cord-017784-4r3fpmlb	115	17	may	may	MD
cord-017784-4r3fpmlb	115	18	be	be	VB
cord-017784-4r3fpmlb	115	19	indicated	indicate	VBN
cord-017784-4r3fpmlb	115	20	only	only	RB
cord-017784-4r3fpmlb	115	21	in	in	IN
cord-017784-4r3fpmlb	115	22	patients	patient	NNS
cord-017784-4r3fpmlb	115	23	with	with	IN
cord-017784-4r3fpmlb	115	24	severe	severe	JJ
cord-017784-4r3fpmlb	115	25	periodontal	periodontal	JJ
cord-017784-4r3fpmlb	115	26	disease	disease	NN
cord-017784-4r3fpmlb	115	27	,	,	,
cord-017784-4r3fpmlb	115	28	putrid	putrid	JJ
cord-017784-4r3fpmlb	115	29	sputum	sputum	NN
cord-017784-4r3fpmlb	115	30	,	,	,
cord-017784-4r3fpmlb	115	31	or	or	CC
cord-017784-4r3fpmlb	115	32	evidence	evidence	NN
cord-017784-4r3fpmlb	115	33	of	of	IN
cord-017784-4r3fpmlb	115	34	necrotizing	necrotize	VBG
cord-017784-4r3fpmlb	115	35	pneumonia	pneumonia	NN
cord-017784-4r3fpmlb	115	36	or	or	CC
cord-017784-4r3fpmlb	115	37	lung	lung	NN
cord-017784-4r3fpmlb	115	38	abscess	abscess	NN
cord-017784-4r3fpmlb	115	39	on	on	IN
cord-017784-4r3fpmlb	115	40	radiographs	radiograph	NNS
cord-017784-4r3fpmlb	115	41	of	of	IN
cord-017784-4r3fpmlb	115	42	the	the	DT
cord-017784-4r3fpmlb	115	43	chest	chest	NN
cord-017784-4r3fpmlb	115	44	.	.	.
cord-017784-4r3fpmlb	116	1	Antiviral	antiviral	JJ
cord-017784-4r3fpmlb	116	2	treatment	treatment	NN
cord-017784-4r3fpmlb	116	3	is	be	VBZ
cord-017784-4r3fpmlb	116	4	recommended	recommend	VBN
cord-017784-4r3fpmlb	116	5	as	as	RB
cord-017784-4r3fpmlb	116	6	early	early	RB
cord-017784-4r3fpmlb	116	7	as	as	IN
cord-017784-4r3fpmlb	116	8	possible	possible	JJ
cord-017784-4r3fpmlb	116	9	for	for	IN
cord-017784-4r3fpmlb	116	10	any	any	DT
cord-017784-4r3fpmlb	116	11	patient	patient	NN
cord-017784-4r3fpmlb	116	12	with	with	IN
cord-017784-4r3fpmlb	116	13	confirmed	confirm	VBN
cord-017784-4r3fpmlb	116	14	or	or	CC
cord-017784-4r3fpmlb	116	15	suspected	suspect	VBN
cord-017784-4r3fpmlb	116	16	influenza	influenza	NN
cord-017784-4r3fpmlb	116	17	pneumonia	pneumonia	NN
cord-017784-4r3fpmlb	116	18	and	and	CC
cord-017784-4r3fpmlb	116	19	should	should	MD
cord-017784-4r3fpmlb	116	20	not	not	RB
cord-017784-4r3fpmlb	116	21	be	be	VB
cord-017784-4r3fpmlb	116	22	delayed	delay	VBN
cord-017784-4r3fpmlb	116	23	by	by	IN
cord-017784-4r3fpmlb	116	24	confirmatory	confirmatory	JJ
cord-017784-4r3fpmlb	116	25	laboratory	laboratory	NN
cord-017784-4r3fpmlb	116	26	testing	testing	NN
cord-017784-4r3fpmlb	116	27	results	result	NNS
cord-017784-4r3fpmlb	116	28	.	.	.
cord-017784-4r3fpmlb	117	1	Neuraminidase	Neuraminidase	NNP
cord-017784-4r3fpmlb	117	2	inhibitors	inhibitor	NNS
cord-017784-4r3fpmlb	117	3	,	,	,
cord-017784-4r3fpmlb	117	4	oseltamivir	oseltamivir	FW
cord-017784-4r3fpmlb	117	5	and	and	CC
cord-017784-4r3fpmlb	117	6	zanamivir	zanamivir	NNP
cord-017784-4r3fpmlb	117	7	,	,	,
cord-017784-4r3fpmlb	117	8	are	be	VBP
cord-017784-4r3fpmlb	117	9	the	the	DT
cord-017784-4r3fpmlb	117	10	agents	agent	NNS
cord-017784-4r3fpmlb	117	11	of	of	IN
cord-017784-4r3fpmlb	117	12	choice	choice	NN
cord-017784-4r3fpmlb	117	13	.	.	.
cord-017784-4r3fpmlb	118	1	The	the	DT
cord-017784-4r3fpmlb	118	2	usual	usual	JJ
cord-017784-4r3fpmlb	118	3	dosing	dosing	NN
cord-017784-4r3fpmlb	118	4	of	of	IN
cord-017784-4r3fpmlb	118	5	oseltamivir	oseltamivir	NN
cord-017784-4r3fpmlb	118	6	for	for	IN
cord-017784-4r3fpmlb	118	7	the	the	DT
cord-017784-4r3fpmlb	118	8	treatment	treatment	NN
cord-017784-4r3fpmlb	118	9	of	of	IN
cord-017784-4r3fpmlb	118	10	influenza	influenza	NN
cord-017784-4r3fpmlb	118	11	is	be	VBZ
cord-017784-4r3fpmlb	118	12	75	75	CD
cord-017784-4r3fpmlb	118	13	mg	mg	PRP
cord-017784-4r3fpmlb	118	14	orally	orally	RB
cord-017784-4r3fpmlb	118	15	twice	twice	RB
cord-017784-4r3fpmlb	118	16	daily	daily	RB
cord-017784-4r3fpmlb	118	17	and	and	CC
cord-017784-4r3fpmlb	118	18	of	of	IN
cord-017784-4r3fpmlb	118	19	zanamivir	zanamivir	NNP
cord-017784-4r3fpmlb	119	1	is	be	VBZ
cord-017784-4r3fpmlb	119	2	10	10	CD
cord-017784-4r3fpmlb	119	3	mg	mg	NN
cord-017784-4r3fpmlb	119	4	(	(	-LRB-
cord-017784-4r3fpmlb	119	5	2	2	CD
cord-017784-4r3fpmlb	119	6	inhalations	inhalations	NNPS
cord-017784-4r3fpmlb	119	7	)	)	-RRB-
cord-017784-4r3fpmlb	119	8	twice	twice	RB
cord-017784-4r3fpmlb	119	9	daily	daily	RB
cord-017784-4r3fpmlb	119	10	.	.	.
cord-017784-4r3fpmlb	120	1	The	the	DT
cord-017784-4r3fpmlb	120	2	recommended	recommend	VBN
cord-017784-4r3fpmlb	120	3	duration	duration	NN
cord-017784-4r3fpmlb	120	4	for	for	IN
cord-017784-4r3fpmlb	120	5	antiviral	antiviral	JJ
cord-017784-4r3fpmlb	120	6	treatment	treatment	NN
cord-017784-4r3fpmlb	120	7	is	be	VBZ
cord-017784-4r3fpmlb	120	8	5	5	CD
cord-017784-4r3fpmlb	120	9	days	day	NNS
cord-017784-4r3fpmlb	120	10	.	.	.
cord-017784-4r3fpmlb	121	1	The	the	DT
cord-017784-4r3fpmlb	121	2	optimal	optimal	JJ
cord-017784-4r3fpmlb	121	3	duration	duration	NN
cord-017784-4r3fpmlb	121	4	of	of	IN
cord-017784-4r3fpmlb	121	5	antibiotic	antibiotic	JJ
cord-017784-4r3fpmlb	121	6	therapy	therapy	NN
cord-017784-4r3fpmlb	121	7	is	be	VBZ
cord-017784-4r3fpmlb	121	8	not	not	RB
cord-017784-4r3fpmlb	121	9	yet	yet	RB
cord-017784-4r3fpmlb	121	10	known	know	VBN
cord-017784-4r3fpmlb	121	11	.	.	.
cord-017784-4r3fpmlb	122	1	BTS	BTS	NNP
cord-017784-4r3fpmlb	122	2	guidelines	guideline	NNS
cord-017784-4r3fpmlb	122	3	[	[	-LRB-
cord-017784-4r3fpmlb	122	4	26	26	CD
cord-017784-4r3fpmlb	122	5	]	]	-RRB-
cord-017784-4r3fpmlb	122	6	propose	propose	VB
cord-017784-4r3fpmlb	122	7	7	7	CD
cord-017784-4r3fpmlb	122	8	-	-	SYM
cord-017784-4r3fpmlb	122	9	10	10	CD
cord-017784-4r3fpmlb	122	10	days	day	NNS
cord-017784-4r3fpmlb	122	11	treatment	treatment	NN
cord-017784-4r3fpmlb	122	12	for	for	IN
cord-017784-4r3fpmlb	122	13	most	most	JJS
cord-017784-4r3fpmlb	122	14	patients	patient	NNS
cord-017784-4r3fpmlb	122	15	with	with	IN
cord-017784-4r3fpmlb	122	16	severe	severe	JJ
cord-017784-4r3fpmlb	122	17	CAP	cap	NN
cord-017784-4r3fpmlb	122	18	,	,	,
cord-017784-4r3fpmlb	122	19	whereas	whereas	IN
cord-017784-4r3fpmlb	122	20	European	european	JJ
cord-017784-4r3fpmlb	122	21	guidelines	guideline	NNS
cord-017784-4r3fpmlb	122	22	[	[	-LRB-
cord-017784-4r3fpmlb	122	23	27	27	CD
cord-017784-4r3fpmlb	122	24	]	]	-RRB-
cord-017784-4r3fpmlb	122	25	suggest	suggest	VBP
cord-017784-4r3fpmlb	122	26	that	that	IN
cord-017784-4r3fpmlb	122	27	the	the	DT
cord-017784-4r3fpmlb	122	28	duration	duration	NN
cord-017784-4r3fpmlb	122	29	of	of	IN
cord-017784-4r3fpmlb	122	30	treatment	treatment	NN
cord-017784-4r3fpmlb	122	31	should	should	MD
cord-017784-4r3fpmlb	122	32	generally	generally	RB
cord-017784-4r3fpmlb	122	33	not	not	RB
cord-017784-4r3fpmlb	122	34	exceed	exceed	VB
cord-017784-4r3fpmlb	122	35	8	8	CD
cord-017784-4r3fpmlb	122	36	days	day	NNS
cord-017784-4r3fpmlb	122	37	in	in	IN
cord-017784-4r3fpmlb	122	38	a	a	DT
cord-017784-4r3fpmlb	122	39	patient	patient	NN
cord-017784-4r3fpmlb	122	40	who	who	WP
cord-017784-4r3fpmlb	122	41	responds	respond	VBZ
cord-017784-4r3fpmlb	122	42	to	to	IN
cord-017784-4r3fpmlb	122	43	initial	initial	JJ
cord-017784-4r3fpmlb	122	44	therapy	therapy	NN
cord-017784-4r3fpmlb	122	45	.	.	.
cord-017784-4r3fpmlb	123	1	The	the	DT
cord-017784-4r3fpmlb	123	2	use	use	NN
cord-017784-4r3fpmlb	123	3	of	of	IN
cord-017784-4r3fpmlb	123	4	biomarkers	biomarker	NNS
cord-017784-4r3fpmlb	123	5	such	such	JJ
cord-017784-4r3fpmlb	123	6	as	as	IN
cord-017784-4r3fpmlb	123	7	procalcitonin	procalcitonin	NNS
cord-017784-4r3fpmlb	123	8	or	or	CC
cord-017784-4r3fpmlb	123	9	the	the	DT
cord-017784-4r3fpmlb	123	10	C	C	NNP
cord-017784-4r3fpmlb	123	11	-	-	HYPH
cord-017784-4r3fpmlb	123	12	reactive	reactive	JJ
cord-017784-4r3fpmlb	123	13	protein	protein	NN
cord-017784-4r3fpmlb	123	14	may	may	MD
cord-017784-4r3fpmlb	123	15	be	be	VB
cord-017784-4r3fpmlb	123	16	useful	useful	JJ
cord-017784-4r3fpmlb	123	17	to	to	TO
cord-017784-4r3fpmlb	123	18	shorten	shorten	VB
cord-017784-4r3fpmlb	123	19	the	the	DT
cord-017784-4r3fpmlb	123	20	duration	duration	NN
cord-017784-4r3fpmlb	123	21	of	of	IN
cord-017784-4r3fpmlb	123	22	antibiotic	antibiotic	JJ
cord-017784-4r3fpmlb	123	23	treatment	treatment	NN
cord-017784-4r3fpmlb	123	24	[	[	-LRB-
cord-017784-4r3fpmlb	123	25	28	28	CD
cord-017784-4r3fpmlb	123	26	]	]	-RRB-
cord-017784-4r3fpmlb	123	27	.	.	.
cord-017784-4r3fpmlb	124	1	The	the	DT
cord-017784-4r3fpmlb	124	2	duration	duration	NN
cord-017784-4r3fpmlb	124	3	of	of	IN
cord-017784-4r3fpmlb	124	4	antibiotic	antibiotic	JJ
cord-017784-4r3fpmlb	124	5	treatment	treatment	NN
cord-017784-4r3fpmlb	124	6	may	may	MD
cord-017784-4r3fpmlb	124	7	be	be	VB
cord-017784-4r3fpmlb	124	8	prolonged	prolong	VBN
cord-017784-4r3fpmlb	124	9	in	in	IN
cord-017784-4r3fpmlb	124	10	patients	patient	NNS
cord-017784-4r3fpmlb	124	11	receiving	receive	VBG
cord-017784-4r3fpmlb	124	12	initial	initial	JJ
cord-017784-4r3fpmlb	124	13	inadequate	inadequate	JJ
cord-017784-4r3fpmlb	124	14	antibiotic	antibiotic	JJ
cord-017784-4r3fpmlb	124	15	therapy	therapy	NN
cord-017784-4r3fpmlb	124	16	,	,	,
cord-017784-4r3fpmlb	124	17	patients	patient	NNS
cord-017784-4r3fpmlb	124	18	with	with	IN
cord-017784-4r3fpmlb	124	19	extrapulmonary	extrapulmonary	JJ
cord-017784-4r3fpmlb	124	20	infection	infection	NN
cord-017784-4r3fpmlb	124	21	(	(	-LRB-
cord-017784-4r3fpmlb	124	22	e.g.	e.g.	RB
cord-017784-4r3fpmlb	124	23	,	,	,
cord-017784-4r3fpmlb	124	24	endocarditis	endocarditis	NN
cord-017784-4r3fpmlb	124	25	,	,	,
cord-017784-4r3fpmlb	124	26	meningitis	meningitis	NN
cord-017784-4r3fpmlb	124	27	)	)	-RRB-
cord-017784-4r3fpmlb	124	28	,	,	,
cord-017784-4r3fpmlb	124	29	patients	patient	NNS
cord-017784-4r3fpmlb	124	30	infected	infect	VBN
cord-017784-4r3fpmlb	124	31	with	with	IN
cord-017784-4r3fpmlb	124	32	multi	multi	JJ
cord-017784-4r3fpmlb	124	33	-	-	JJ
cord-017784-4r3fpmlb	124	34	drugresistant	drugresistant	JJ
cord-017784-4r3fpmlb	124	35	organism	organism	NN
cord-017784-4r3fpmlb	124	36	(	(	-LRB-
cord-017784-4r3fpmlb	124	37	e.g.	e.g.	RB
cord-017784-4r3fpmlb	124	38	,	,	,
cord-017784-4r3fpmlb	124	39	S.	S.	NNP
cord-017784-4r3fpmlb	124	40	aureus	aureus	NN
cord-017784-4r3fpmlb	124	41	)	)	-RRB-
cord-017784-4r3fpmlb	124	42	and	and	CC
cord-017784-4r3fpmlb	124	43	patients	patient	NNS
cord-017784-4r3fpmlb	124	44	with	with	IN
cord-017784-4r3fpmlb	124	45	necrotizing	necrotize	VBG
cord-017784-4r3fpmlb	124	46	pneumonia	pneumonia	NN
cord-017784-4r3fpmlb	124	47	.	.	.
cord-017784-4r3fpmlb	125	1	Regarding	regard	VBG
cord-017784-4r3fpmlb	125	2	the	the	DT
cord-017784-4r3fpmlb	125	3	dosing	dosing	NN
cord-017784-4r3fpmlb	125	4	(	(	-LRB-
cord-017784-4r3fpmlb	125	5	Table	table	NN
cord-017784-4r3fpmlb	125	6	5	5	CD
cord-017784-4r3fpmlb	125	7	.	.	.
cord-017784-4r3fpmlb	125	8	3	3	LS
cord-017784-4r3fpmlb	125	9	)	)	-RRB-
cord-017784-4r3fpmlb	125	10	,	,	,
cord-017784-4r3fpmlb	125	11	there	there	EX
cord-017784-4r3fpmlb	125	12	are	be	VBP
cord-017784-4r3fpmlb	125	13	many	many	JJ
cord-017784-4r3fpmlb	125	14	considerations	consideration	NNS
cord-017784-4r3fpmlb	125	15	to	to	TO
cord-017784-4r3fpmlb	125	16	be	be	VB
cord-017784-4r3fpmlb	125	17	made	make	VBN
cord-017784-4r3fpmlb	125	18	when	when	WRB
cord-017784-4r3fpmlb	125	19	caring	care	VBG
cord-017784-4r3fpmlb	125	20	for	for	IN
cord-017784-4r3fpmlb	125	21	elderly	elderly	JJ
cord-017784-4r3fpmlb	125	22	patients	patient	NNS
cord-017784-4r3fpmlb	125	23	:	:	:
cord-017784-4r3fpmlb	125	24	multiple	multiple	JJ
cord-017784-4r3fpmlb	125	25	comorbidities	comorbiditie	NNS
cord-017784-4r3fpmlb	125	26	,	,	,
cord-017784-4r3fpmlb	125	27	polypharmacy	polypharmacy	FW
cord-017784-4r3fpmlb	125	28	potentially	potentially	RB
cord-017784-4r3fpmlb	125	29	resulting	result	VBG
cord-017784-4r3fpmlb	125	30	in	in	IN
cord-017784-4r3fpmlb	125	31	drug	drug	NN
cord-017784-4r3fpmlb	125	32	interactions	interaction	NNS
cord-017784-4r3fpmlb	125	33	,	,	,
cord-017784-4r3fpmlb	125	34	pharmacokinetic	pharmacokinetic	JJ
cord-017784-4r3fpmlb	125	35	and	and	CC
cord-017784-4r3fpmlb	125	36	pharmacodynamic	pharmacodynamic	JJ
cord-017784-4r3fpmlb	125	37	changes	change	NNS
cord-017784-4r3fpmlb	125	38	that	that	WDT
cord-017784-4r3fpmlb	125	39	can	can	MD
cord-017784-4r3fpmlb	125	40	result	result	VB
cord-017784-4r3fpmlb	125	41	in	in	IN
cord-017784-4r3fpmlb	125	42	altered	altered	JJ
cord-017784-4r3fpmlb	125	43	drug	drug	NN
cord-017784-4r3fpmlb	125	44	metabolism	metabolism	NN
cord-017784-4r3fpmlb	125	45	and	and	CC
cord-017784-4r3fpmlb	125	46	subsequent	subsequent	JJ
cord-017784-4r3fpmlb	125	47	toxic	toxic	JJ
cord-017784-4r3fpmlb	125	48	effects	effect	NNS
cord-017784-4r3fpmlb	125	49	of	of	IN
cord-017784-4r3fpmlb	125	50	drug	drug	NN
cord-017784-4r3fpmlb	125	51	accumulation	accumulation	NN
cord-017784-4r3fpmlb	125	52	[	[	-LRB-
cord-017784-4r3fpmlb	125	53	29	29	CD
cord-017784-4r3fpmlb	125	54	]	]	-RRB-
cord-017784-4r3fpmlb	125	55	.	.	.
cord-017784-4r3fpmlb	126	1	Despite	despite	IN
cord-017784-4r3fpmlb	126	2	the	the	DT
cord-017784-4r3fpmlb	126	3	complexity	complexity	NN
cord-017784-4r3fpmlb	126	4	of	of	IN
cord-017784-4r3fpmlb	126	5	all	all	DT
cord-017784-4r3fpmlb	126	6	of	of	IN
cord-017784-4r3fpmlb	126	7	these	these	DT
cord-017784-4r3fpmlb	126	8	changes	change	NNS
cord-017784-4r3fpmlb	126	9	,	,	,
cord-017784-4r3fpmlb	126	10	however	however	RB
cord-017784-4r3fpmlb	126	11	,	,	,
cord-017784-4r3fpmlb	126	12	the	the	DT
cord-017784-4r3fpmlb	126	13	singular	singular	JJ
cord-017784-4r3fpmlb	126	14	impairment	impairment	NN
cord-017784-4r3fpmlb	126	15	that	that	WDT
cord-017784-4r3fpmlb	126	16	most	most	RBS
cord-017784-4r3fpmlb	126	17	significantly	significantly	RB
cord-017784-4r3fpmlb	126	18	influences	influence	VBZ
cord-017784-4r3fpmlb	126	19	the	the	DT
cord-017784-4r3fpmlb	126	20	medical	medical	JJ
cord-017784-4r3fpmlb	126	21	management	management	NN
cord-017784-4r3fpmlb	126	22	of	of	IN
cord-017784-4r3fpmlb	126	23	infection	infection	NN
cord-017784-4r3fpmlb	126	24	in	in	IN
cord-017784-4r3fpmlb	126	25	older	old	JJR
cord-017784-4r3fpmlb	126	26	patients	patient	NNS
cord-017784-4r3fpmlb	126	27	is	be	VBZ
cord-017784-4r3fpmlb	126	28	the	the	DT
cord-017784-4r3fpmlb	126	29	decline	decline	NN
cord-017784-4r3fpmlb	126	30	in	in	IN
cord-017784-4r3fpmlb	126	31	renal	renal	JJ
cord-017784-4r3fpmlb	126	32	function	function	NN
cord-017784-4r3fpmlb	126	33	commonly	commonly	RB
cord-017784-4r3fpmlb	126	34	observed	observe	VBD
cord-017784-4r3fpmlb	126	35	in	in	IN
cord-017784-4r3fpmlb	126	36	this	this	DT
cord-017784-4r3fpmlb	126	37	group	group	NN
cord-017784-4r3fpmlb	126	38	.	.	.
cord-017784-4r3fpmlb	127	1	In	in	IN
cord-017784-4r3fpmlb	127	2	patients	patient	NNS
cord-017784-4r3fpmlb	127	3	with	with	IN
cord-017784-4r3fpmlb	127	4	impaired	impaired	JJ
cord-017784-4r3fpmlb	127	5	renal	renal	JJ
cord-017784-4r3fpmlb	127	6	function	function	NN
cord-017784-4r3fpmlb	127	7	,	,	,
cord-017784-4r3fpmlb	127	8	antibiotics	antibiotic	NNS
cord-017784-4r3fpmlb	127	9	should	should	MD
cord-017784-4r3fpmlb	127	10	always	always	RB
cord-017784-4r3fpmlb	127	11	be	be	VB
cord-017784-4r3fpmlb	127	12	started	start	VBN
cord-017784-4r3fpmlb	127	13	at	at	IN
cord-017784-4r3fpmlb	127	14	full	full	JJ
cord-017784-4r3fpmlb	127	15	initial	initial	JJ
cord-017784-4r3fpmlb	127	16	doses	dose	NNS
cord-017784-4r3fpmlb	127	17	and	and	CC
cord-017784-4r3fpmlb	127	18	then	then	RB
cord-017784-4r3fpmlb	127	19	adjusted	adjust	VBN
cord-017784-4r3fpmlb	127	20	based	base	VBN
cord-017784-4r3fpmlb	127	21	on	on	IN
cord-017784-4r3fpmlb	127	22	renal	renal	JJ
cord-017784-4r3fpmlb	127	23	function	function	NN
cord-017784-4r3fpmlb	127	24	.	.	.
cord-017784-4r3fpmlb	128	1	Lower	low	JJR
cord-017784-4r3fpmlb	128	2	respiratory	respiratory	JJ
cord-017784-4r3fpmlb	128	3	tract	tract	NN
cord-017784-4r3fpmlb	128	4	infections	infection	NNS
cord-017784-4r3fpmlb	128	5	,	,	,
cord-017784-4r3fpmlb	128	6	including	include	VBG
cord-017784-4r3fpmlb	128	7	pneumonia	pneumonia	NN
cord-017784-4r3fpmlb	128	8	and	and	CC
cord-017784-4r3fpmlb	128	9	exacerbation	exacerbation	NN
cord-017784-4r3fpmlb	128	10	of	of	IN
cord-017784-4r3fpmlb	128	11	chronic	chronic	JJ
cord-017784-4r3fpmlb	128	12	obstructive	obstructive	JJ
cord-017784-4r3fpmlb	128	13	pulmonary	pulmonary	JJ
cord-017784-4r3fpmlb	128	14	disease	disease	NN
cord-017784-4r3fpmlb	128	15	,	,	,
cord-017784-4r3fpmlb	128	16	are	be	VBP
cord-017784-4r3fpmlb	128	17	among	among	IN
cord-017784-4r3fpmlb	128	18	the	the	DT
cord-017784-4r3fpmlb	128	19	most	most	RBS
cord-017784-4r3fpmlb	128	20	common	common	JJ
cord-017784-4r3fpmlb	128	21	causes	cause	NNS
cord-017784-4r3fpmlb	128	22	of	of	IN
cord-017784-4r3fpmlb	128	23	ARF	arf	NN
cord-017784-4r3fpmlb	128	24	in	in	IN
cord-017784-4r3fpmlb	128	25	elderly	elderly	JJ
cord-017784-4r3fpmlb	128	26	people	people	NNS
cord-017784-4r3fpmlb	128	27	and	and	CC
cord-017784-4r3fpmlb	128	28	the	the	DT
cord-017784-4r3fpmlb	128	29	most	most	RBS
cord-017784-4r3fpmlb	128	30	important	important	JJ
cord-017784-4r3fpmlb	128	31	cause	cause	NN
cord-017784-4r3fpmlb	128	32	of	of	IN
cord-017784-4r3fpmlb	128	33	hospitalization	hospitalization	NN
cord-017784-4r3fpmlb	128	34	.	.	.
cord-017784-4r3fpmlb	129	1	Moreover	moreover	RB
cord-017784-4r3fpmlb	129	2	pulmonary	pulmonary	JJ
cord-017784-4r3fpmlb	129	3	infection	infection	NN
cord-017784-4r3fpmlb	129	4	is	be	VBZ
cord-017784-4r3fpmlb	129	5	also	also	RB
cord-017784-4r3fpmlb	129	6	the	the	DT
cord-017784-4r3fpmlb	129	7	most	most	RBS
cord-017784-4r3fpmlb	129	8	frequent	frequent	JJ
cord-017784-4r3fpmlb	129	9	single	single	JJ
cord-017784-4r3fpmlb	129	10	cause	cause	NN
cord-017784-4r3fpmlb	129	11	of	of	IN
cord-017784-4r3fpmlb	129	12	ARDS	ARDS	NNP
cord-017784-4r3fpmlb	129	13	.	.	.
cord-017784-4r3fpmlb	130	1	In	in	IN
cord-017784-4r3fpmlb	130	2	the	the	DT
cord-017784-4r3fpmlb	130	3	management	management	NN
cord-017784-4r3fpmlb	130	4	of	of	IN
cord-017784-4r3fpmlb	130	5	respiratory	respiratory	JJ
cord-017784-4r3fpmlb	130	6	failure	failure	NN
cord-017784-4r3fpmlb	130	7	,	,	,
cord-017784-4r3fpmlb	130	8	it	-PRON-	PRP
cord-017784-4r3fpmlb	130	9	is	be	VBZ
cord-017784-4r3fpmlb	130	10	mandatory	mandatory	JJ
cord-017784-4r3fpmlb	130	11	reversing	reversing	NN
cord-017784-4r3fpmlb	130	12	and/or	and/or	CC
cord-017784-4r3fpmlb	130	13	preventing	prevent	VBG
cord-017784-4r3fpmlb	130	14	tissue	tissue	NN
cord-017784-4r3fpmlb	130	15	hypoxia	hypoxia	NN
cord-017784-4r3fpmlb	130	16	through	through	IN
cord-017784-4r3fpmlb	130	17	conventional	conventional	JJ
cord-017784-4r3fpmlb	130	18	oxygen	oxygen	NN
cord-017784-4r3fpmlb	130	19	therapy	therapy	NN
cord-017784-4r3fpmlb	130	20	or	or	CC
cord-017784-4r3fpmlb	130	21	invasive	invasive	JJ
cord-017784-4r3fpmlb	130	22	or	or	CC
cord-017784-4r3fpmlb	130	23	non	non	JJ
cord-017784-4r3fpmlb	130	24	-	-	JJ
cord-017784-4r3fpmlb	130	25	invasive	invasive	JJ
cord-017784-4r3fpmlb	130	26	mechanical	mechanical	JJ
cord-017784-4r3fpmlb	130	27	ventilation	ventilation	NN
cord-017784-4r3fpmlb	130	28	.	.	.
cord-017784-4r3fpmlb	131	1	Besides	besides	RB
cord-017784-4r3fpmlb	131	2	,	,	,
cord-017784-4r3fpmlb	131	3	early	early	JJ
cord-017784-4r3fpmlb	131	4	administration	administration	NN
cord-017784-4r3fpmlb	131	5	of	of	IN
cord-017784-4r3fpmlb	131	6	appropriate	appropriate	JJ
cord-017784-4r3fpmlb	131	7	antimicrobials	antimicrobial	NNS
cord-017784-4r3fpmlb	131	8	has	have	VBZ
cord-017784-4r3fpmlb	131	9	been	be	VBN
cord-017784-4r3fpmlb	131	10	postulated	postulate	VBN
cord-017784-4r3fpmlb	131	11	as	as	IN
cord-017784-4r3fpmlb	131	12	a	a	DT
cord-017784-4r3fpmlb	131	13	key	key	JJ
cord-017784-4r3fpmlb	131	14	strategy	strategy	NN
cord-017784-4r3fpmlb	131	15	in	in	IN
cord-017784-4r3fpmlb	131	16	the	the	DT
cord-017784-4r3fpmlb	131	17	survival	survival	NN
cord-017784-4r3fpmlb	131	18	of	of	IN
cord-017784-4r3fpmlb	131	19	patients	patient	NNS
cord-017784-4r3fpmlb	131	20	with	with	IN
cord-017784-4r3fpmlb	131	21	very	very	RB
cord-017784-4r3fpmlb	131	22	severe	severe	JJ
cord-017784-4r3fpmlb	131	23	infections	infection	NNS
cord-017784-4r3fpmlb	131	24	requiring	require	VBG
cord-017784-4r3fpmlb	131	25	intensive	intensive	JJ
cord-017784-4r3fpmlb	131	26	care	care	NN
cord-017784-4r3fpmlb	131	27	unit	unit	NN
cord-017784-4r3fpmlb	131	28	admission	admission	NN
cord-017784-4r3fpmlb	131	29	taking	take	VBG
cord-017784-4r3fpmlb	131	30	into	into	IN
cord-017784-4r3fpmlb	131	31	account	account	NN
cord-017784-4r3fpmlb	131	32	the	the	DT
cord-017784-4r3fpmlb	131	33	most	most	JJS
cord-017784-4r3fpmlb	131	34	risk	risk	NN
cord-017784-4r3fpmlb	131	35	of	of	IN
cord-017784-4r3fpmlb	131	36	adverse	adverse	JJ
cord-017784-4r3fpmlb	131	37	events	event	NNS
cord-017784-4r3fpmlb	131	38	of	of	IN
cord-017784-4r3fpmlb	131	39	an	an	DT
cord-017784-4r3fpmlb	131	40	antimicrobial	antimicrobial	NN
cord-017784-4r3fpmlb	131	41	in	in	IN
cord-017784-4r3fpmlb	131	42	a	a	DT
cord-017784-4r3fpmlb	131	43	frail	frail	JJ
cord-017784-4r3fpmlb	131	44	elderly	elderly	JJ
cord-017784-4r3fpmlb	131	45	patient	patient	NN
cord-017784-4r3fpmlb	131	46	.	.	.
cord-017784-4r3fpmlb	132	1	1	1	LS
cord-017784-4r3fpmlb	132	2	.	.	.
cord-017784-4r3fpmlb	133	1	Acute	acute	JJ
cord-017784-4r3fpmlb	133	2	respiratory	respiratory	JJ
cord-017784-4r3fpmlb	133	3	failure	failure	NN
cord-017784-4r3fpmlb	133	4	is	be	VBZ
cord-017784-4r3fpmlb	133	5	a	a	DT
cord-017784-4r3fpmlb	133	6	frequent	frequent	JJ
cord-017784-4r3fpmlb	133	7	complication	complication	NN
cord-017784-4r3fpmlb	133	8	in	in	IN
cord-017784-4r3fpmlb	133	9	elderly	elderly	JJ
cord-017784-4r3fpmlb	133	10	patients	patient	NNS
cord-017784-4r3fpmlb	133	11	.	.	.
cord-017784-4r3fpmlb	134	1	2	2	LS
cord-017784-4r3fpmlb	134	2	.	.	.
cord-017784-4r3fpmlb	135	1	Infections	infection	NNS
cord-017784-4r3fpmlb	135	2	(	(	-LRB-
cord-017784-4r3fpmlb	135	3	CAP	cap	NN
cord-017784-4r3fpmlb	135	4	and	and	CC
cord-017784-4r3fpmlb	135	5	AECOPD	AECOPD	NNP
cord-017784-4r3fpmlb	135	6	)	)	-RRB-
cord-017784-4r3fpmlb	135	7	are	be	VBP
cord-017784-4r3fpmlb	135	8	among	among	IN
cord-017784-4r3fpmlb	135	9	the	the	DT
cord-017784-4r3fpmlb	135	10	most	most	RBS
cord-017784-4r3fpmlb	135	11	frequent	frequent	JJ
cord-017784-4r3fpmlb	135	12	triggering	trigger	VBG
cord-017784-4r3fpmlb	135	13	causes	cause	NNS
cord-017784-4r3fpmlb	135	14	of	of	IN
cord-017784-4r3fpmlb	135	15	ARF	arf	NN
cord-017784-4r3fpmlb	135	16	in	in	IN
cord-017784-4r3fpmlb	135	17	advanced	advanced	JJ
cord-017784-4r3fpmlb	135	18	aged	aged	JJ
cord-017784-4r3fpmlb	135	19	patients	patient	NNS
cord-017784-4r3fpmlb	135	20	.	.	.
cord-017784-4r3fpmlb	136	1	3	3	LS
cord-017784-4r3fpmlb	136	2	.	.	.
cord-017784-4r3fpmlb	137	1	Antimicrobials	antimicrobial	NNS
cord-017784-4r3fpmlb	137	2	are	be	VBP
cord-017784-4r3fpmlb	137	3	the	the	DT
cord-017784-4r3fpmlb	137	4	cornerstone	cornerstone	NN
cord-017784-4r3fpmlb	137	5	of	of	IN
cord-017784-4r3fpmlb	137	6	therapy	therapy	NN
cord-017784-4r3fpmlb	137	7	for	for	IN
cord-017784-4r3fpmlb	137	8	CAP	CAP	NNP
cord-017784-4r3fpmlb	137	9	and	and	CC
cord-017784-4r3fpmlb	137	10	in	in	IN
cord-017784-4r3fpmlb	137	11	COPD	COPD	NNP
cord-017784-4r3fpmlb	137	12	exacerbations	exacerbation	NNS
cord-017784-4r3fpmlb	137	13	when	when	WRB
cord-017784-4r3fpmlb	137	14	patients	patient	NNS
cord-017784-4r3fpmlb	137	15	have	have	VBP
cord-017784-4r3fpmlb	137	16	clinical	clinical	JJ
cord-017784-4r3fpmlb	137	17	signs	sign	NNS
cord-017784-4r3fpmlb	137	18	of	of	IN
cord-017784-4r3fpmlb	137	19	a	a	DT
cord-017784-4r3fpmlb	137	20	bacterial	bacterial	JJ
cord-017784-4r3fpmlb	137	21	infection	infection	NN
cord-017784-4r3fpmlb	137	22	.	.	.
cord-017784-4r3fpmlb	138	1	4	4	LS
cord-017784-4r3fpmlb	138	2	.	.	.
cord-017784-4r3fpmlb	139	1	Antibiotic	antibiotic	JJ
cord-017784-4r3fpmlb	139	2	duration	duration	NN
cord-017784-4r3fpmlb	139	3	should	should	MD
cord-017784-4r3fpmlb	139	4	be	be	VB
cord-017784-4r3fpmlb	139	5	as	as	RB
cord-017784-4r3fpmlb	139	6	shorter	short	JJR
cord-017784-4r3fpmlb	139	7	as	as	IN
cord-017784-4r3fpmlb	139	8	possible	possible	JJ
cord-017784-4r3fpmlb	139	9	,	,	,
cord-017784-4r3fpmlb	139	10	based	base	VBN
cord-017784-4r3fpmlb	139	11	on	on	IN
cord-017784-4r3fpmlb	139	12	the	the	DT
cord-017784-4r3fpmlb	139	13	pathogen	pathogen	NN
cord-017784-4r3fpmlb	139	14	,	,	,
cord-017784-4r3fpmlb	139	15	clinical	clinical	JJ
cord-017784-4r3fpmlb	139	16	response	response	NN
cord-017784-4r3fpmlb	139	17	,	,	,
cord-017784-4r3fpmlb	139	18	and	and	CC
cord-017784-4r3fpmlb	139	19	presence	presence	NN
cord-017784-4r3fpmlb	139	20	of	of	IN
cord-017784-4r3fpmlb	139	21	complications	complication	NNS
cord-017784-4r3fpmlb	139	22	.	.	.
cord-017784-4r3fpmlb	140	1	5	5	LS
cord-017784-4r3fpmlb	140	2	.	.	.
cord-017784-4r3fpmlb	141	1	A	a	DT
cord-017784-4r3fpmlb	141	2	judicious	judicious	JJ
cord-017784-4r3fpmlb	141	3	use	use	NN
cord-017784-4r3fpmlb	141	4	of	of	IN
cord-017784-4r3fpmlb	141	5	antibiotic	antibiotic	JJ
cord-017784-4r3fpmlb	141	6	therapy	therapy	NN
cord-017784-4r3fpmlb	141	7	in	in	IN
cord-017784-4r3fpmlb	141	8	the	the	DT
cord-017784-4r3fpmlb	141	9	respiratory	respiratory	JJ
cord-017784-4r3fpmlb	141	10	tract	tract	NN
cord-017784-4r3fpmlb	141	11	infections	infection	NNS
cord-017784-4r3fpmlb	141	12	is	be	VBZ
cord-017784-4r3fpmlb	141	13	critical	critical	JJ
cord-017784-4r3fpmlb	141	14	in	in	IN
cord-017784-4r3fpmlb	141	15	the	the	DT
cord-017784-4r3fpmlb	141	16	era	era	NN
cord-017784-4r3fpmlb	141	17	of	of	IN
cord-017784-4r3fpmlb	141	18	antibiotic	antibiotic	JJ
cord-017784-4r3fpmlb	141	19	resistance	resistance	NN
cord-017784-4r3fpmlb	141	20	.	.	.
cord-017784-4r3fpmlb	142	1	The	the	DT
cord-017784-4r3fpmlb	142	2	impact	impact	NN
cord-017784-4r3fpmlb	142	3	of	of	IN
cord-017784-4r3fpmlb	142	4	immunosenescence	immunosenescence	NN
cord-017784-4r3fpmlb	142	5	on	on	IN
cord-017784-4r3fpmlb	142	6	pulmonary	pulmonary	JJ
cord-017784-4r3fpmlb	142	7	disease	disease	NN
cord-017784-4r3fpmlb	142	8	Acute	acute	JJ
cord-017784-4r3fpmlb	142	9	respiratory	respiratory	JJ
cord-017784-4r3fpmlb	142	10	failure	failure	NN
cord-017784-4r3fpmlb	142	11	in	in	IN
cord-017784-4r3fpmlb	142	12	the	the	DT
cord-017784-4r3fpmlb	142	13	elderly	elderly	JJ
cord-017784-4r3fpmlb	142	14	:	:	:
cord-017784-4r3fpmlb	142	15	etiology	etiology	NN
cord-017784-4r3fpmlb	142	16	,	,	,
cord-017784-4r3fpmlb	142	17	emergency	emergency	NN
cord-017784-4r3fpmlb	142	18	diagnosis	diagnosis	NN
cord-017784-4r3fpmlb	142	19	and	and	CC
cord-017784-4r3fpmlb	142	20	prognosis	prognosis	NN
cord-017784-4r3fpmlb	142	21	Respiratory	respiratory	JJ
cord-017784-4r3fpmlb	142	22	failure	failure	NN
cord-017784-4r3fpmlb	143	1	Acute	acute	JJ
cord-017784-4r3fpmlb	143	2	respiratory	respiratory	JJ
cord-017784-4r3fpmlb	143	3	failure	failure	NN
cord-017784-4r3fpmlb	143	4	in	in	IN
cord-017784-4r3fpmlb	143	5	the	the	DT
cord-017784-4r3fpmlb	143	6	elderly	elderly	JJ
cord-017784-4r3fpmlb	143	7	:	:	:
cord-017784-4r3fpmlb	144	1	diagnosis	diagnosis	NN
cord-017784-4r3fpmlb	144	2	and	and	CC
cord-017784-4r3fpmlb	144	3	prognosis	prognosis	NN
cord-017784-4r3fpmlb	144	4	acute	acute	JJ
cord-017784-4r3fpmlb	144	5	respiratory	respiratory	JJ
cord-017784-4r3fpmlb	144	6	distress	distress	NN
cord-017784-4r3fpmlb	144	7	syndrome	syndrome	NN
cord-017784-4r3fpmlb	144	8	,	,	,
cord-017784-4r3fpmlb	144	9	and	and	CC
cord-017784-4r3fpmlb	144	10	early	early	JJ
cord-017784-4r3fpmlb	144	11	immune	immune	JJ
cord-017784-4r3fpmlb	144	12	-	-	HYPH
cord-017784-4r3fpmlb	144	13	modulator	modulator	NN
cord-017784-4r3fpmlb	144	14	therapy	therapy	NN
cord-017784-4r3fpmlb	145	1	The	the	DT
cord-017784-4r3fpmlb	145	2	acute	acute	JJ
cord-017784-4r3fpmlb	145	3	respiratory	respiratory	JJ
cord-017784-4r3fpmlb	145	4	distress	distress	NN
cord-017784-4r3fpmlb	145	5	syndrome	syndrome	NN
cord-017784-4r3fpmlb	145	6	Acute	acute	JJ
cord-017784-4r3fpmlb	145	7	respiratory	respiratory	JJ
cord-017784-4r3fpmlb	145	8	distress	distress	NN
cord-017784-4r3fpmlb	145	9	syndrome	syndrome	NN
cord-017784-4r3fpmlb	145	10	Acute	acute	JJ
cord-017784-4r3fpmlb	145	11	respiratory	respiratory	JJ
cord-017784-4r3fpmlb	145	12	distress	distress	NN
cord-017784-4r3fpmlb	145	13	syndrome	syndrome	NN
cord-017784-4r3fpmlb	145	14	:	:	:
cord-017784-4r3fpmlb	145	15	the	the	DT
cord-017784-4r3fpmlb	145	16	Berlin	Berlin	NNP
cord-017784-4r3fpmlb	145	17	definition	definition	NN
cord-017784-4r3fpmlb	145	18	Antibiotic	antibiotic	JJ
cord-017784-4r3fpmlb	145	19	therapy	therapy	NN
cord-017784-4r3fpmlb	145	20	and	and	CC
cord-017784-4r3fpmlb	145	21	treatment	treatment	NN
cord-017784-4r3fpmlb	145	22	failure	failure	NN
cord-017784-4r3fpmlb	145	23	in	in	IN
cord-017784-4r3fpmlb	145	24	patients	patient	NNS
cord-017784-4r3fpmlb	145	25	hospitalized	hospitalize	VBN
cord-017784-4r3fpmlb	145	26	for	for	IN
cord-017784-4r3fpmlb	145	27	acute	acute	JJ
cord-017784-4r3fpmlb	145	28	exacerbations	exacerbation	NNS
cord-017784-4r3fpmlb	145	29	of	of	IN
cord-017784-4r3fpmlb	145	30	chronic	chronic	JJ
cord-017784-4r3fpmlb	145	31	obstructive	obstructive	JJ
cord-017784-4r3fpmlb	145	32	pulmonary	pulmonary	JJ
cord-017784-4r3fpmlb	145	33	disease	disease	NN
cord-017784-4r3fpmlb	145	34	Global	Global	NNP
cord-017784-4r3fpmlb	145	35	Initiative	Initiative	NNP
cord-017784-4r3fpmlb	145	36	for	for	IN
cord-017784-4r3fpmlb	145	37	Chronic	Chronic	NNP
cord-017784-4r3fpmlb	145	38	Obstructive	Obstructive	NNP
cord-017784-4r3fpmlb	145	39	Lung	Lung	NNP
cord-017784-4r3fpmlb	145	40	Diseases	Diseases	NNPS
cord-017784-4r3fpmlb	145	41	.	.	.
cord-017784-4r3fpmlb	146	1	Global	global	JJ
cord-017784-4r3fpmlb	146	2	strategy	strategy	NN
cord-017784-4r3fpmlb	146	3	for	for	IN
cord-017784-4r3fpmlb	146	4	the	the	DT
cord-017784-4r3fpmlb	146	5	diagnosis	diagnosis	NN
cord-017784-4r3fpmlb	146	6	,	,	,
cord-017784-4r3fpmlb	146	7	management	management	NN
cord-017784-4r3fpmlb	146	8	and	and	CC
cord-017784-4r3fpmlb	146	9	prevention	prevention	NN
cord-017784-4r3fpmlb	146	10	of	of	IN
cord-017784-4r3fpmlb	146	11	chronic	chronic	JJ
cord-017784-4r3fpmlb	146	12	obstructive	obstructive	JJ
cord-017784-4r3fpmlb	146	13	pulmonary	pulmonary	JJ
cord-017784-4r3fpmlb	146	14	disease	disease	NN
cord-017784-4r3fpmlb	146	15	Infection	infection	NN
cord-017784-4r3fpmlb	146	16	in	in	IN
cord-017784-4r3fpmlb	146	17	the	the	DT
cord-017784-4r3fpmlb	146	18	pathogenesis	pathogenesis	NN
cord-017784-4r3fpmlb	146	19	and	and	CC
cord-017784-4r3fpmlb	146	20	course	course	NN
cord-017784-4r3fpmlb	146	21	of	of	IN
cord-017784-4r3fpmlb	146	22	chronic	chronic	JJ
cord-017784-4r3fpmlb	146	23	obstructive	obstructive	JJ
cord-017784-4r3fpmlb	146	24	pulmonary	pulmonary	JJ
cord-017784-4r3fpmlb	146	25	disease	disease	NN
cord-017784-4r3fpmlb	146	26	Infective	Infective	NNP
cord-017784-4r3fpmlb	146	27	exacerbations	exacerbation	NNS
cord-017784-4r3fpmlb	146	28	of	of	IN
cord-017784-4r3fpmlb	146	29	chronic	chronic	JJ
cord-017784-4r3fpmlb	146	30	bronchitis	bronchitis	NN
cord-017784-4r3fpmlb	146	31	:	:	:
cord-017784-4r3fpmlb	146	32	relation	relation	NN
cord-017784-4r3fpmlb	146	33	between	between	IN
cord-017784-4r3fpmlb	146	34	bacteriologic	bacteriologic	JJ
cord-017784-4r3fpmlb	146	35	etiology	etiology	NN
cord-017784-4r3fpmlb	146	36	and	and	CC
cord-017784-4r3fpmlb	146	37	lung	lung	NN
cord-017784-4r3fpmlb	146	38	function	function	NN
cord-017784-4r3fpmlb	147	1	The	the	DT
cord-017784-4r3fpmlb	147	2	role	role	NN
cord-017784-4r3fpmlb	147	3	of	of	IN
cord-017784-4r3fpmlb	147	4	atypical	atypical	JJ
cord-017784-4r3fpmlb	147	5	pathogens	pathogen	NNS
cord-017784-4r3fpmlb	147	6	in	in	IN
cord-017784-4r3fpmlb	147	7	exacerbations	exacerbation	NNS
cord-017784-4r3fpmlb	147	8	of	of	IN
cord-017784-4r3fpmlb	147	9	chronic	chronic	JJ
cord-017784-4r3fpmlb	147	10	obstructive	obstructive	JJ
cord-017784-4r3fpmlb	147	11	pulmonary	pulmonary	JJ
cord-017784-4r3fpmlb	147	12	disease	disease	NN
cord-017784-4r3fpmlb	147	13	Infectious	infectious	JJ
cord-017784-4r3fpmlb	147	14	etiology	etiology	NN
cord-017784-4r3fpmlb	147	15	of	of	IN
cord-017784-4r3fpmlb	147	16	acute	acute	JJ
cord-017784-4r3fpmlb	147	17	exacerbations	exacerbation	NNS
cord-017784-4r3fpmlb	147	18	of	of	IN
cord-017784-4r3fpmlb	147	19	chronic	chronic	JJ
cord-017784-4r3fpmlb	147	20	bronchitis	bronchitis	NN
cord-017784-4r3fpmlb	147	21	Prevalence	prevalence	NN
cord-017784-4r3fpmlb	147	22	of	of	IN
cord-017784-4r3fpmlb	147	23	viral	viral	JJ
cord-017784-4r3fpmlb	147	24	infection	infection	NN
cord-017784-4r3fpmlb	147	25	detected	detect	VBN
cord-017784-4r3fpmlb	147	26	by	by	IN
cord-017784-4r3fpmlb	147	27	PCR	PCR	NNP
cord-017784-4r3fpmlb	147	28	and	and	CC
cord-017784-4r3fpmlb	147	29	RT	RT	NNP
cord-017784-4r3fpmlb	147	30	-	-	HYPH
cord-017784-4r3fpmlb	147	31	PCR	PCR	NNP
cord-017784-4r3fpmlb	147	32	in	in	IN
cord-017784-4r3fpmlb	147	33	patients	patient	NNS
cord-017784-4r3fpmlb	147	34	with	with	IN
cord-017784-4r3fpmlb	147	35	acute	acute	JJ
cord-017784-4r3fpmlb	147	36	exacerbation	exacerbation	NN
cord-017784-4r3fpmlb	147	37	of	of	IN
cord-017784-4r3fpmlb	147	38	COPD	COPD	NNP
cord-017784-4r3fpmlb	147	39	:	:	:
cord-017784-4r3fpmlb	147	40	a	a	DT
cord-017784-4r3fpmlb	147	41	systematic	systematic	JJ
cord-017784-4r3fpmlb	147	42	review	review	NN
cord-017784-4r3fpmlb	147	43	Sputum	sputum	NN
cord-017784-4r3fpmlb	147	44	colour	colour	NN
cord-017784-4r3fpmlb	147	45	and	and	CC
cord-017784-4r3fpmlb	147	46	bacteria	bacteria	NNS
cord-017784-4r3fpmlb	147	47	in	in	IN
cord-017784-4r3fpmlb	147	48	chronic	chronic	JJ
cord-017784-4r3fpmlb	147	49	bronchitis	bronchitis	NN
cord-017784-4r3fpmlb	147	50	exacerbations	exacerbation	NNS
cord-017784-4r3fpmlb	147	51	:	:	:
cord-017784-4r3fpmlb	147	52	a	a	DT
cord-017784-4r3fpmlb	147	53	pooled	pool	VBN
cord-017784-4r3fpmlb	147	54	analysis	analysis	NN
cord-017784-4r3fpmlb	147	55	Pathogen	pathogen	NN
cord-017784-4r3fpmlb	147	56	-	-	HYPH
cord-017784-4r3fpmlb	147	57	directed	direct	VBN
cord-017784-4r3fpmlb	147	58	therapy	therapy	NN
cord-017784-4r3fpmlb	147	59	in	in	IN
cord-017784-4r3fpmlb	147	60	acute	acute	JJ
cord-017784-4r3fpmlb	147	61	exacerbations	exacerbation	NNS
cord-017784-4r3fpmlb	147	62	of	of	IN
cord-017784-4r3fpmlb	147	63	COPD	COPD	NNP
cord-017784-4r3fpmlb	147	64	Pneumonia	Pneumonia	NNP
cord-017784-4r3fpmlb	147	65	in	in	IN
cord-017784-4r3fpmlb	147	66	the	the	DT
cord-017784-4r3fpmlb	147	67	very	very	RB
cord-017784-4r3fpmlb	147	68	old	old	JJ
cord-017784-4r3fpmlb	147	69	Community	community	NN
cord-017784-4r3fpmlb	147	70	-	-	HYPH
cord-017784-4r3fpmlb	147	71	acquired	acquire	VBN
cord-017784-4r3fpmlb	147	72	pneumonia	pneumonia	NN
cord-017784-4r3fpmlb	147	73	in	in	IN
cord-017784-4r3fpmlb	147	74	very	very	RB
cord-017784-4r3fpmlb	147	75	elderly	elderly	JJ
cord-017784-4r3fpmlb	147	76	patients	patient	NNS
cord-017784-4r3fpmlb	147	77	:	:	:
cord-017784-4r3fpmlb	147	78	causative	causative	JJ
cord-017784-4r3fpmlb	147	79	organisms	organism	NNS
cord-017784-4r3fpmlb	147	80	,	,	,
cord-017784-4r3fpmlb	147	81	clinical	clinical	JJ
cord-017784-4r3fpmlb	147	82	characteristics	characteristic	NNS
cord-017784-4r3fpmlb	147	83	,	,	,
cord-017784-4r3fpmlb	147	84	and	and	CC
cord-017784-4r3fpmlb	147	85	outcomes	outcome	NNS
cord-017784-4r3fpmlb	148	1	Bacterial	bacterial	JJ
cord-017784-4r3fpmlb	148	2	pneumonia	pneumonia	NN
cord-017784-4r3fpmlb	148	3	in	in	IN
cord-017784-4r3fpmlb	148	4	the	the	DT
cord-017784-4r3fpmlb	148	5	elderly	elderly	JJ
cord-017784-4r3fpmlb	148	6	:	:	:
cord-017784-4r3fpmlb	149	1	the	the	DT
cord-017784-4r3fpmlb	149	2	observations	observation	NNS
cord-017784-4r3fpmlb	149	3	of	of	IN
cord-017784-4r3fpmlb	149	4	Sir	Sir	NNP
cord-017784-4r3fpmlb	149	5	William	William	NNP
cord-017784-4r3fpmlb	149	6	Osler	Osler	NNP
cord-017784-4r3fpmlb	149	7	in	in	IN
cord-017784-4r3fpmlb	149	8	retrospect	retrospect	JJ
cord-017784-4r3fpmlb	149	9	Community	Community	NNP
cord-017784-4r3fpmlb	149	10	-	-	HYPH
cord-017784-4r3fpmlb	149	11	acquired	acquire	VBN
cord-017784-4r3fpmlb	149	12	pneumonia	pneumonia	NN
cord-017784-4r3fpmlb	149	13	requiring	require	VBG
cord-017784-4r3fpmlb	149	14	hospitalization	hospitalization	NN
cord-017784-4r3fpmlb	149	15	among	among	IN
cord-017784-4r3fpmlb	149	16	U.S.	U.S.	NNP
cord-017784-4r3fpmlb	149	17	adults	adult	NNS
cord-017784-4r3fpmlb	150	1	Pneumonia	pneumonia	NN
cord-017784-4r3fpmlb	150	2	in	in	IN
cord-017784-4r3fpmlb	150	3	the	the	DT
cord-017784-4r3fpmlb	150	4	elderly	elderly	JJ
cord-017784-4r3fpmlb	150	5	:	:	:
cord-017784-4r3fpmlb	150	6	a	a	DT
cord-017784-4r3fpmlb	150	7	review	review	NN
cord-017784-4r3fpmlb	150	8	of	of	IN
cord-017784-4r3fpmlb	150	9	the	the	DT
cord-017784-4r3fpmlb	150	10	epidemiology	epidemiology	NN
cord-017784-4r3fpmlb	150	11	,	,	,
cord-017784-4r3fpmlb	150	12	pathogenesis	pathogenesis	NN
cord-017784-4r3fpmlb	150	13	,	,	,
cord-017784-4r3fpmlb	150	14	microbiology	microbiology	NN
cord-017784-4r3fpmlb	150	15	,	,	,
cord-017784-4r3fpmlb	150	16	and	and	CC
cord-017784-4r3fpmlb	150	17	clinical	clinical	JJ
cord-017784-4r3fpmlb	150	18	features	feature	VBZ
cord-017784-4r3fpmlb	150	19	Aspiration	aspiration	NN
cord-017784-4r3fpmlb	150	20	-	-	HYPH
cord-017784-4r3fpmlb	150	21	related	relate	VBN
cord-017784-4r3fpmlb	150	22	pulmonary	pulmonary	JJ
cord-017784-4r3fpmlb	150	23	syndromes	syndrome	NNS
cord-017784-4r3fpmlb	151	1	Guidelines	guideline	NNS
cord-017784-4r3fpmlb	151	2	for	for	IN
cord-017784-4r3fpmlb	151	3	the	the	DT
cord-017784-4r3fpmlb	151	4	management	management	NN
cord-017784-4r3fpmlb	151	5	of	of	IN
cord-017784-4r3fpmlb	151	6	community	community	NN
cord-017784-4r3fpmlb	151	7	-	-	HYPH
cord-017784-4r3fpmlb	151	8	acquired	acquire	VBN
cord-017784-4r3fpmlb	151	9	pneumonia	pneumonia	NN
cord-017784-4r3fpmlb	151	10	in	in	IN
cord-017784-4r3fpmlb	151	11	the	the	DT
cord-017784-4r3fpmlb	151	12	elderly	elderly	JJ
cord-017784-4r3fpmlb	151	13	patient	patient	NN
cord-017784-4r3fpmlb	151	14	Infectious	Infectious	NNP
cord-017784-4r3fpmlb	151	15	Diseases	Diseases	NNPS
cord-017784-4r3fpmlb	151	16	Society	Society	NNP
cord-017784-4r3fpmlb	151	17	of	of	IN
cord-017784-4r3fpmlb	151	18	America/	america/	JJ
cord-017784-4r3fpmlb	151	19	American	American	NNP
cord-017784-4r3fpmlb	151	20	Thoracic	Thoracic	NNP
cord-017784-4r3fpmlb	151	21	Society	Society	NNP
cord-017784-4r3fpmlb	151	22	consensus	consensus	NN
cord-017784-4r3fpmlb	151	23	guidelines	guideline	NNS
cord-017784-4r3fpmlb	151	24	on	on	IN
cord-017784-4r3fpmlb	151	25	the	the	DT
cord-017784-4r3fpmlb	151	26	management	management	NN
cord-017784-4r3fpmlb	151	27	of	of	IN
cord-017784-4r3fpmlb	151	28	community	community	NN
cord-017784-4r3fpmlb	151	29	-	-	HYPH
cord-017784-4r3fpmlb	151	30	acquired	acquire	VBN
cord-017784-4r3fpmlb	151	31	pneumonia	pneumonia	NN
cord-017784-4r3fpmlb	151	32	in	in	IN
cord-017784-4r3fpmlb	151	33	adults	adult	NNS
cord-017784-4r3fpmlb	151	34	Guidelines	Guidelines	NNPS
cord-017784-4r3fpmlb	151	35	for	for	IN
cord-017784-4r3fpmlb	151	36	the	the	DT
cord-017784-4r3fpmlb	151	37	management	management	NN
cord-017784-4r3fpmlb	151	38	of	of	IN
cord-017784-4r3fpmlb	151	39	communityacquired	communityacquired	JJ
cord-017784-4r3fpmlb	151	40	pneumonia	pneumonia	NN
cord-017784-4r3fpmlb	151	41	in	in	IN
cord-017784-4r3fpmlb	151	42	adults	adult	NNS
cord-017784-4r3fpmlb	152	1	:	:	:
cord-017784-4r3fpmlb	152	2	update	update	VB
cord-017784-4r3fpmlb	152	3	Guidelines	guideline	NNS
cord-017784-4r3fpmlb	152	4	for	for	IN
cord-017784-4r3fpmlb	152	5	the	the	DT
cord-017784-4r3fpmlb	152	6	management	management	NN
cord-017784-4r3fpmlb	152	7	of	of	IN
cord-017784-4r3fpmlb	152	8	adult	adult	NN
cord-017784-4r3fpmlb	152	9	lower	low	JJR
cord-017784-4r3fpmlb	152	10	respiratory	respiratory	JJ
cord-017784-4r3fpmlb	152	11	tract	tract	NN
cord-017784-4r3fpmlb	152	12	infections	infection	NNS
cord-017784-4r3fpmlb	152	13	Blood	blood	NN
cord-017784-4r3fpmlb	152	14	biomarkers	biomarker	NNS
cord-017784-4r3fpmlb	152	15	for	for	IN
cord-017784-4r3fpmlb	152	16	personalized	personalized	JJ
cord-017784-4r3fpmlb	152	17	treatment	treatment	NN
cord-017784-4r3fpmlb	152	18	and	and	CC
cord-017784-4r3fpmlb	152	19	patient	patient	NN
cord-017784-4r3fpmlb	152	20	management	management	NN
cord-017784-4r3fpmlb	152	21	decisions	decision	NNS
cord-017784-4r3fpmlb	152	22	in	in	IN
cord-017784-4r3fpmlb	152	23	community	community	NN
cord-017784-4r3fpmlb	152	24	-	-	HYPH
cord-017784-4r3fpmlb	152	25	acquired	acquire	VBN
cord-017784-4r3fpmlb	152	26	pneumonia	pneumonia	NN
cord-017784-4r3fpmlb	152	27	Antibacterial	antibacterial	JJ
cord-017784-4r3fpmlb	152	28	agents	agent	NNS
cord-017784-4r3fpmlb	152	29	in	in	IN
cord-017784-4r3fpmlb	152	30	the	the	DT
cord-017784-4r3fpmlb	152	31	elderly	elderly	JJ