id author title date pages extension mime words sentences flesch summary cache txt cord-018497-oy7hsrpt Beutels, Philippe P.A. Economic aspects of vaccines and vaccination: a global perspective 2005 .txt text/plain 6370 285 47 The share of health-care expenditures in the Gross Domestic Product (GDP) of most industrialised countries has increased from 3%-5% in the early sixties to 7%-11% in 2001 (from 5% to 14% in the USA) [1] This rise has been attributed to medical advances (increasing the number and technological complexity of medical interventions), population aging, sociological changes (more, but smaller families and less familial support for the elderly) and insufficient productivity increases in the services sector. Because of the very long time spans over which benefits accrue, the analysis of most vaccination programs is very sensitive to discounting (of costs as well as health effects). It seems clear, though, that the smallpox eradication program and the establishment of the EPI have generated enormous benefits, not only by directly protecting against important vaccine-preventable diseases, but also by providing opportunities for health education and infrastructure in developing countries [30] . ./cache/cord-018497-oy7hsrpt.txt ./txt/cord-018497-oy7hsrpt.txt