id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-298989-qk0k2lmz	, Umesh	Identification of new anti-nCoV drug chemical compounds from Indian spices exploiting SARS-CoV-2 main protease as target	2020-05-13		.txt	text/plain	3226	179	52	title: Identification of new anti-nCoV drug chemical compounds from Indian spices exploiting SARS-CoV-2 main protease as target Carnosol exhibited highest binding affinity -8.2 Kcal/mol and strong and stable interactions with the amino acid residues present on the active site of SARS-CoV-2 Mpro. Our virtual screening results suggest that these small chemical molecules can be used as potential inhibitors against SARS-CoV-2 Mpro and may have an anti-viral effect on nCoV. SARS-CoV-2 main protease, a potential drug target, crystal structure (PDB-ID: 6Y84) was available and used for docking simulation and identification of potential drug molecule form Indian spices. Details of various kinds of interaction shown between the amino acids near the active site of SARS-CoV-2 main protease along with their respective inhibitor constant (Ki) and biological source and binding energy. Potential inhibitor of COVID-19 main protease (Mpro) from several medicinal plant compounds by molecular docking study	./cache/cord-298989-qk0k2lmz.txt	./txt/cord-298989-qk0k2lmz.txt