id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-335137-5qt286kc	Chatterjee, Swapan K.	Molecular Pathogenesis, Immunopathogenesis and Novel Therapeutic Strategy Against COVID-19	2020-08-11		.txt	text/plain	7124	369	47	It is believed that interaction between angiotensin converting enzyme 2 (ACE2) cell receptor and viral Spike protein mediates the coronavirus entry into human respiratory epithelial cells and establishes the host tropism. The most significant surface protein is spike glycoprotein which interferes in establishing the association between the human respiratory epithelial cells to the virus via cell surface membrane receptor angiotensin-converting enzyme 2 (ACE2) and finally establishes the host tropism (Li et al., 2003) . A recent study suggests that prediction of SARS-CoV-2 spike glycoprotein structure, glycan shield pattern and pattern of glycosylation has great inference on understanding the viral camouflage as well as the outline of cell entry, and also facilitate the development of new small-molecule drugs, vaccines, antibodies, and screening of the human host targets (Song et al., 2018) . Various studies have proved that SARS-CoV-2 infection initiation and spread of disease into the host cells mainly depends upon S protein priming by TMPRSS2 (Transmembrane protease serine type 2), the serine protease.	./cache/cord-335137-5qt286kc.txt	./txt/cord-335137-5qt286kc.txt