id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-011793-hlktpla4	Rice, Todd W.	In Defense of Evidence-based Medicine for the Treatment of COVID-19 Acute Respiratory Distress Syndrome	2020-07-17		.txt	text/plain	1828	81	42	Although the desire to try to treat these patients with already approved drugs is understandable, what is less understandable is the desire in medical publications and on social media to abandon the principles of evidence-based critical care that we have established over the last 3 decades (9), because "I have never seen patients with ARDS act like this." Large, well-designed, multicenter randomized trials have set the foundation of an evidence-based practice of how to produce the best outcomes for critically ill patients. Instead, improved outcomes are seen through understanding and implementing best practices derived via strong scientific evidence generated from well-designed randomized controlled trials into the routine care of critically ill patients. Maintaining other principles of good critical care, as demonstrated in large, multicenter randomized trials, will also improve outcomes in these critically ill patients with COVID-19, even if "COVID-19 is completely different from other intensive care unit syndromes." Conservative fluid management once out of shock and without renal failure increases time alive and free from ventilation (15) .	./cache/cord-011793-hlktpla4.txt	./txt/cord-011793-hlktpla4.txt