id author title date pages extension mime words sentences flesch summary cache txt cord-013212-lx614fy4 Nobel, Yael R. Reply to GASTRO-D-20-01179 2020-10-14 .txt text/plain 588 37 55 1 In their letter titled "Focusing on gastrointestinal symptoms in COVID-19 is far from enough", the authors suggest that in patients with COVID-19, stool-based testing for leukocytes and erythrocytes/occult blood, rather than patient-reported gastrointestinal symptoms, should be considered. We reviewed their data with interest but remain unconvinced that stool-based testing adds value to the clinical diagnosis of diarrhea among patients with known or suspected COVID-19. In our study, conducted among outpatients with respiratory symptoms being evaluated for COVID-19 during the height of the pandemic, the presence of gastrointestinal symptoms (diarrhea or nausea/vomiting) was associated with a 70% increased risk of testing positive for SARS-CoV-2. In sum, our study found that the presence of gastrointestinal symptoms (diarrhea with or without nausea/vomiting) predicted a positive test for SARS-CoV-2 among patients with respiratory symptoms at the height of the COVID-19 pandemic. ./cache/cord-013212-lx614fy4.txt ./txt/cord-013212-lx614fy4.txt