id author title date pages extension mime words sentences flesch summary cache txt cord-026764-eag13h3p Sumner, O. Age-appropriate antibiotics 2020-06-12 .txt text/plain 833 61 53 Several recent clinical studies have investigated hydroxychloroquine for COVID-19 patients but these have been at high risk of bias, hence the need for large randomised placebo-controlled clinical trials to determine the potential benefits and harms before any role can be recommended. Hydroxychloroquine is one such drug with hypothesised mechanisms of action and in vitro evidence supporting the inhibition of severe acute respiratory syndrome coronavirus 2. Treating paediatric patients in an Urgent Dental Care Centre at Newcastle Dental Hospital, we have worryingly seen a shocking proportion of children who have been prescribed age-inappropriate, suboptimal doses of antibiotics and subsequently referred for treatment as 'unresponsive to antibiotics' . 4 The Centre for Evidence Based Medicine's commentary on PPE in primary care concerns general medical practice. In vitro antiviral activity and projection of optimized dosing design of hydroxychloroquine for the treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) ./cache/cord-026764-eag13h3p.txt ./txt/cord-026764-eag13h3p.txt