id author title date pages extension mime words sentences flesch summary cache txt cord-031061-48xwfr9i Abdullah, Abdullah Innate Immune-mediated Antiviral Response to SARS-CoV-2 and Convalescent sera a potential Prophylactic and Therapeutic Agent to Tackle COVID-19 2020-08-16 .txt text/plain 2530 153 43 title: Innate Immune-mediated Antiviral Response to SARS-CoV-2 and Convalescent sera a potential Prophylactic and Therapeutic Agent to Tackle COVID-19 The convalescent sera of the recovered COVID-19 patients are containing antiviral neutralizing antibodies and is used therapeutically for infected individuals by SARS-CoV-2 and for the purpose of prophylaxis in exposed individuals. Three SARS-CoV-1 infected patients were treated with 500ml of convalescent sera, the reduction in viral titer and mortality were recorded (39) . Three MERS infected patients were also treated with Convalescent or Passive antibody therapy, two of them produce nAbs and remaining one not (40) , this study highlights the limitation in using of convalescent sera it means that the recovered individual may not have enough titer of nAbs (41) . The available information on the use of convalescent sera or passive immunization for the treatment of SARS-CoV-2 suggests that early administration of convalescent serum reduces viral abundance and was found safe. ./cache/cord-031061-48xwfr9i.txt ./txt/cord-031061-48xwfr9i.txt