id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-033778-u2r0neyc	Taban, EM	Observational study of therapeutic bronchoscopy in critical hypoxaemic ventilated patients with COVID-19 at Mediclinic Midstream Private Hospital in Pretoria, South Africa	2020-10-13		.txt	text/plain	2577	146	48	Flexible fibreoptic bronchoscopy (FFB) has been used for years as a diagnostic and therapeutic adjunct for the diagnosis of potential airway obstruction as a cause of acute respiratory failure or in the management of hypoxaemia ventilated patients. To evaluate the use of FFB as a rescue therapy in mechanically ventilated patients with severe hypoxaemic respiratory failure caused by COVID-19. Patients with severe COVID-19 pneumonia who have persistent hypoxaemia despite the resolution of inflammatory parameters may respond to FFB with removal of mucus plugs. These patients had severe COVID-19 pneumonia with the following characteristics: severe refractory hypoxaemia despite maximal mechanical ventilatory support, including proning and significant deterioration from previous minimal ventilator settings. We have demonstrated that some patients with severe COVID-19 pneumonia and persistent hypoxaemia despite resolution of inflammatory parameters may respond to FFB following removal of mucus plugs.	./cache/cord-033778-u2r0neyc.txt	./txt/cord-033778-u2r0neyc.txt