id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-251945-v077hhgk	Titanji, Boghuma K	Response to Correspondence: Baricitinib as Treatment of COVID-19 Friend or Foe of the Pancreas? Cerda-Contreras et.al	2020-08-14		.txt	text/plain	728	53	44	The cytopathic effects from local virus replication and significant inflammation associated with severe disease may contribute to pancreatic tissue damage in patients with COVID-19. New onset type I diabetes mellitus and worsening type II diabetes mellitus have been linked to damage of pancreatic islet cells in patients with COVID-19 3 , further supporting the tropism of SARS-CoV2 for the pancreas and the potential damaging effects to that organ. We also note that in addition, the patient received treatment with steroids and propofol, both of which have been independently associated with acute pancreatitis 4-6 . In targeting the hyper-inflammation that is associated with severe COVID-19, timing of immunomodulatory therapy is key, and combining potent immuno-modulators requires caution to avoid tipping the balance in favor of enhanced viral replication. Coronavirus Disease-19 (COVID-19) associated with severe acute pancreatitis: Case report on three family members	./cache/cord-251945-v077hhgk.txt	./txt/cord-251945-v077hhgk.txt