id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-252279-0gozdv43	Pal, Amit	Hydroxychloroquine and Covid-19: A Cellular and Molecular Biology Based Update	2020-06-10		.txt	text/plain	3858	207	39	Without a therapeutic vaccine or specific antiviral drugs, and with a desperate attempt to find a cure against novel Corona Virus Disease 2019 (Covid-19) [1] , the limelight was shifted to hydoxychloroquine (derivative of chloroquine that has antimalarial, antiinflammatory, immunosuppressive and antiautophagy activities [2, 3] ; upon a tweet by US president Mr. Donald J. The main aim of this review is to discuss the mode of action of hydroxychloroquine at cellular and molecular levels, that potentially support the clinical efficacy and few adverse side effects observed in Covid-19 patients treated with hydroxychloroquine, which may further help in improving the clinical outcomes by modifying or altering the drug itself or its restricted use in certain individuals by enforcing strict inclusion and exclusion criteria. Due to its cellular and molecular effects as discussed in previous sections, quite a few clinical trials are studying the effectiveness and safety of hydroxychloroquine (also chloroquine) for Covid-19 (https://clinicaltrials.gov/ct2/ results?cond=%22wuhan?coronavirus%22).	./cache/cord-252279-0gozdv43.txt	./txt/cord-252279-0gozdv43.txt