id author title date pages extension mime words sentences flesch summary cache txt cord-252328-ov4r3ple Ortoleva, Jamel Consider Adjunctive Ketamine in Mechanically Ventilated COVID-19 Patients 2020-04-28 .txt text/plain 482 45 40 authors: Ortoleva, Jamel title: Consider Adjunctive Ketamine in Mechanically Ventilated COVID-19 Patients 1 The predominant cause of critical illness and death in coronavirus patients is acute respiratory distress syndrome (ARDS). 2 Another important cause which is frequently present with ARDS is cytokine storm can result in vasodilatory shock and multiorgan dysfunction. 4, 5 Anesthesiologists are in a unique position to blend a unique skill set of knowledge in mechanical ventilation, hemodynamic management, procedural expertise, and pharmacology to treat the most critically ill COVID-19 patients. 6 It would be exciting to study ketamine as part of a sedation regimen, in double blindrandomized fashion, for patients with respiratory failure due to COVID-19. COVID-19: consider cytokine storm syndromes and immunosuppression. Evaluation of the Efficacy and Safety of Sarilumab in Hospitalized Patients with COVID-19 A Study to Evaluate the Safety and Efficacy of Tocilizumab in Patients with Severe COVID-19 Pneumonia (COVACTA) ./cache/cord-252328-ov4r3ple.txt ./txt/cord-252328-ov4r3ple.txt