id author title date pages extension mime words sentences flesch summary cache txt cord-252374-obl6pfpf Zaninotto, Martina Cardiac troponin I in SARS-CoV-2-patients: the additional prognostic value of serial monitoring 2020-10-01 .txt text/plain 2956 156 40 Aim of our study has been to investigate in COVID-19 patients the kinetics of release of cardiac troponin I and time course of its concentrations, measured with a high-sensitivity method (hs-TnI), in order to verify if serial measurements may provide additional and clinically useful information in identifying the underlying mechanisms of release and patients' risk stratification and prognosis. Several papers in the recent literature have highlighted the complex interaction between the cardiovascular system and COVID-19, showing myocardial injury in 20 to 40% of hospitalized patients (14, 15) : heart failure, acute coronary syndrome (ACS), arrhythmia and myocarditis, the most frequent complications, are all associated with elevated cardiac troponins, evidenced in particular by high-sensitivity immunoassays (16, 17) . These results seem to provide clinically relevant and specific informations regarding the type and the severity of myocardial injury associated to COVID 19 disease (21, 22) , thus assuring additional clinical data for stratifying risk, establishing the prognosis, managing patients and gaining important epidemiological insight on cardiac involvement in SARS-CoV-2 patients (23, 24) . ./cache/cord-252374-obl6pfpf.txt ./txt/cord-252374-obl6pfpf.txt