id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-253124-s3pa4n8a	Dhamad, Ahmed E.	COVID-19: molecular and serological detection methods	2020-10-07		.txt	text/plain	3370	188	50	Since COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was declared as a pandemic disease by the World Health Organization in early 2020, many countries, organizations and companies have tried to find the best way to diagnose the virus and contain its spreading. And the top keywords that searched were: COVID-19, SARS-CoV-2, coronavirus, genomic RNA, protein structure, ACE2, transmission, symptoms, molecular detection methods, serological detection methods, rRT-PCR, ID NOW COVID-19, isothermal amplification, CRISPR, SARS-CoV-2 DETECTR, LAMP, recombinase polymerase amplification (RPA), Lateral flow assay (LFA) and Enzyme-linked immunosorbent assay (ELISA). In this method (e.g., SARS-CoV-2 DETECTR), the RNA virus is extracted from a specimen and designated regions of N2, E, RP genes are amplified at 62 C for 20 min by specific primes through Reverse Transcription Loop-mediated Isothermal Amplification (RT-LAMP) approach Lamb et al., 2020; Hong et al., 2004) . Unlike molecular methods, serological methods (also called antibody tests) can be applied to detect past and current SARS-CoV-2 infection and monitor the progress of the disease periods and immune response.	./cache/cord-253124-s3pa4n8a.txt	./txt/cord-253124-s3pa4n8a.txt