id author title date pages extension mime words sentences flesch summary cache txt cord-255365-fog62qdu Goldstein, Neal D. On the importance of early testing even when imperfect in a pandemic such as COVID-19 2020-08-03 .txt text/plain 1482 83 49 bias in identified cases of SARS-CoV-2 infections will vary in the face of unknown data surrounding test sensitivity and specificity. The true prevalence of COVID-19 will vary in the tested population (e.g., whether a drive-thru public event, clinical referral, group home, etc.), therefore we allowed for a hypothetical range from 0% to 50%. When the true prevalence of COVID-19 infection is low, as at the start of a pandemic, there will be a greater number of false positives, even under excellent specificity. If we assume 25% prevalence of disease in the tested population, we could realistically anticipate between 0 and 75 false positive results, and between 0 and 100 false negative results per 1000 tests. Serosurveys employing antibody assays can thereby inform public health surveillance regarding the extent of the population who have been infected at any point with SARS-CoV-2, and track herd immunity thresholds. ./cache/cord-255365-fog62qdu.txt ./txt/cord-255365-fog62qdu.txt