id author title date pages extension mime words sentences flesch summary cache txt cord-256255-wqpndl46 Wang, Lang Prolonged prothrombin time at admission predicts poor clinical outcome in COVID-19 patients 2020-10-06 .txt text/plain 3707 216 51 CONCLUSION: Prothrombin time, concentration of fibrin degradation products, respiration rate and age were predictive factors for clinical outcomes of COVID-19 patients. The elevation of D-dimer and fibrin degradation products (FDP), shortened or prolonged prothrombin time (PT), abnormal platelet count, occurrence of thrombosis or bleeding and complication of disseminated intravascular coagulation (DIC) were observed in COVID-19 patients in different clinical stages [6, 7] . The factors with significant differences between the death and survival groups, including age, sex, comorbidities, respiration rate, platelet count, PT, APTT, D-dimer and FDP, were included in the regression. Univariate analysis showed that age, sex, hypertension, cerebrovascular disease, chronic kidney disease, COPD, respiration rate, PT, concentrations of D-dimer and FDP may contribute to the death risk of COVID-19 patients. As the platelet count and several parameters of coagulation were significantly different between those who died and survivors, the prognostic value of these factors for COVID-19 was analyzed using logistic regression. ./cache/cord-256255-wqpndl46.txt ./txt/cord-256255-wqpndl46.txt