id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-256309-hbdrobn1	Kow, Chia Siang	Meta-analysis of Effectiveness of Statins in Patients with Severe COVID-19	2020-08-12		.txt	text/plain	962	52	44	Some researchers [6] have also argued that statins might promote the development of a more severe course of COVID-19 due to activation of the inflammasome pathway in acute respiratory distress syndrome, leading to increased pro-inflammatory interleukin-18 (IL-18) levels and subsequent cytokine storm [7, 8] . Individual observational studies [9] [10] [11] [12] have since reported on this area and we carried out a meta-analysis to summarise the existing evidence on the effect of statins on the clinical outcomes of COVID-19 from adjusted analyses. We searched PubMed, Google Scholar, and medRxiv (preprint repository) databases, up to 27 July 2020, for studies evaluating the risk of severe illness and/or mortality in COVID-19 among statin users compared to non-statin users, with the following keywords and their MeSH terms: Studies were included if they are of cohort or case-control design, included patients with confirmed COVID-19, and with data available to compare the risk of severe illness and/or mortality among statin users compared to non-statin users in adjusted analyses.	./cache/cord-256309-hbdrobn1.txt	./txt/cord-256309-hbdrobn1.txt