id author title date pages extension mime words sentences flesch summary cache txt cord-256862-038rrdtp Oland, Gabriel Prospective Clinical Validation of 3D Printed Nasopharyngeal Swabs for Diagnosis of COVID-19 2020-10-22 .txt text/plain 2003 106 46 70 adult patients (37 COVID-positive and 33 COVID-negative) underwent consecutive diagnostic RT-PCR testing, with a flocked swab followed by one or two 3D printed swabs. The decision to use 3D printed nasopharyngeal swabs during the COVID-19 pandemic should be strongly considered by clinical and research laboratories. In the span of days-to-weeks, numerous 3D printing companies went through an iterative design process (6, 7) to meet the requirements of the NP swab: 1) to collect an adequate patient specimen from the nasopharyngeal mucosa, and 2) to elute the sample into a reverse transcription polymerase chain reaction (RT-PCR) assay without affecting the quality of results. A minimum sample size of 30 COVID-positive and 30 COVID-negative patients for each NP swab type was chosen based on the FDA's recommendation for clinical evaluation of new diagnostics eligible for emergency use authorization (EUA). ./cache/cord-256862-038rrdtp.txt ./txt/cord-256862-038rrdtp.txt