id author title date pages extension mime words sentences flesch summary cache txt cord-257781-ybpliz32 Jones, Eben Subcutaneous Emphysema, Pneumomediastinum, and Pneumothorax in Critically Ill Patients With Coronavirus Disease 2019: A Retrospective Cohort Study 2020-09-17 .txt text/plain 3472 190 44 IMPORTANCE: Management of severe coronavirus disease 2019 relies on advanced respiratory support modalities including invasive mechanical ventilation, continuous positive airway pressure, and noninvasive ventilation, all of which are associated with the development of subcutaneous emphysema, pneumomediastinum, and pneumothorax (herein collectively termed barotrauma). Barotrauma cases had longer illness duration prior to critical care admission (10 vs 7 d; interquartile range, 8–14 and 6–10, respectively; p = 0.073) and were more often treated with continuous positive airway pressure or noninvasive ventilation as the initial modality of advanced respiratory support (87.5% vs 36.0%; p = 0.007). Subcutaneous emphysema, pneumomediastinum, and pneumothorax-herein collectively termed "barotrauma" (referring to the manifestation, rather than etiologic mechanism, of airway tract damage and resultant extra-alveolar air)-are known complications of all forms of positive pressure respiratory support and are associated with multiple organ failure and death (6) . ./cache/cord-257781-ybpliz32.txt ./txt/cord-257781-ybpliz32.txt