id author title date pages extension mime words sentences flesch summary cache txt cord-260723-y4ow6n8r Dorey-Stein, Zachariah L. Case Series: Failure of imaging & biochemical markers to capture disease progression in COVID-19 2020-09-19 .txt text/plain 1595 90 44 We report four individuals admitted for acute respiratory failure due to COVID-19 who demonstrated significant clinical improvement prior to discharge and subsequently were readmitted with worsening respiratory failure, elevated inflammatory markers and worsening chest imaging. In this case series we report four individuals admitted for acute respiratory failure due to COVID-19 who demonstrated significant clinical improvement prior to discharge and subsequently were readmitted with worsening respiratory failure and significant new findings on admission computed tomography (CT) of the chest. Due to an increasing oxygen requirement, rising inflammatory markers, and a worsening left upper lobe opacity she was treated with methylprednisolone 500 mg daily and hydroxychloroquine for presumed cytokine storm. His oxygen requirement was weaned to 3 liters and inflammatory markers trended down, and he was discharged on the sixth day of his admission back to a skilled nursing facility to complete a 6-day course of prednisone 40 mg daily. ./cache/cord-260723-y4ow6n8r.txt ./txt/cord-260723-y4ow6n8r.txt