id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-261070-cvj1t0gi	Zhang, Xue	ACEI/ARB Use and Risk of Infection or Severity or Mortality of COVID-19: A Systematic Review and Meta-analysis	2020-05-15		.txt	text/plain	2982	166	49	title: ACEI/ARB Use and Risk of Infection or Severity or Mortality of COVID-19: A Systematic Review and Meta-analysis To provide a quantitative estimate of the association of ACEI/ARB use with critical or mortal risk in COVID-19 patients, the ORs (most adjusted, if available) and the corresponding 95% CIs were abstracted from published articles. In subgroup analyses by type of data, no significant higher risk of mortality was When our analysis limited to the studies only included patient with antihypertensive indication, a significant lower risk of mortality was observed among those with ACEI/ARB use (OR=0.62, 95%CI 0.38-1.02, P=0.059; Figure 3 ). After excluded studies enrolled patients with hypertension but without antihypertensive treatment, the meta-analysis of four studies also found that ACEI/ARB exposure was associated with a lower risk of mortality compared those with non-ACEI/ARB antihypertensive drugs (OR=0.48, 95% CI 0.29-0.81, P=0.006; I 2 =0%). Further analysis limited to studies only included patients with drug indication found a lower risk of mortality among those with ACEI/ARB use.	./cache/cord-261070-cvj1t0gi.txt	./txt/cord-261070-cvj1t0gi.txt