id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-261471-3msk5ggc	Whyte, Martin B.	The contribution of diabetic micro-angiopathy to adverse outcomes in COVID-19	2020-05-13		.txt	text/plain	1175	77	39	Increasing evidence points to endothelial cell dysfunction as a key pathophysiological factor in severe coronavirus disease-19 (COVID-19), manifested by platelet aggregation, microthrombi and altered vasomotor tone. Major risk groups identified for adverse outcomes in COVID-19 are diabetes, and those from the Black, Asian and ethnic minority (BAME) populations. Major risk groups identified for adverse outcomes in are diabetes, and those from the Black, Asian and ethnic minority (BAME) populations. In this article, we propose that pre-existing endothelial dysfunction of microangiopathy, more commonly evident in diabetes and BAME groups, makes an individual vulnerable to the subsequent 'endothelitis' of COVID-19 infection. In this article, we propose that pre-existing endothelial dysfunction of microangiopathy, more commonly evident in diabetes and BAME groups, makes an individual vulnerable to the subsequent 'endothelitis' of COVID-19 infection. [10; 20] Microvascular disease and endothelial dysfunction may underlie adverse outcomes in COVID-19 and may represent the pathophysiological key missing link that identifies susceptible populations and may require specific treatment.	./cache/cord-261471-3msk5ggc.txt	./txt/cord-261471-3msk5ggc.txt