id author title date pages extension mime words sentences flesch summary cache txt cord-261577-h86kidhs Páramo, José A. Pulmonary Embolism, Pulmonary Microvascular Thrombosis, or Both in COVID-19? 2020-07-22 .txt text/plain 361 28 36 authors: Páramo, José A. lar damage with focal fibrin clusters mixed with mononuclear inflammatory cells as the primary mechanism of respiratory distress associated with COVID-19 and, therefore, disseminated fibrin deposits occur in the pulmonary microcirculation as a consequence of the ongoing inflammatory stimuli leading to acute lung injury and respiratory damage. 5, 6 Indeed, it has been suggested the acronym MicroCLOTS (microvascular COVID-19 lung vessels obstructive thromboinflammatory syndrome) as the pathophysiological mechanism for the acute respiratory distress syndrome caused by this coronavirus. 7 In line with this pathophysiological approach, a recent study indicates direct viral infection of endothelial cells and diffuse endothelial inflammation in lungs in patients who developed progressive respiratory failure. Acute pulmonary embolism in COVID-19 patients on CT angiography and Microvascular COVID-19 lung vessels obstructive thromboinflammatory syndrome (MicroCLOTS): an atypical acute respiratory distress syndrome working hypothesis ./cache/cord-261577-h86kidhs.txt ./txt/cord-261577-h86kidhs.txt