id author title date pages extension mime words sentences flesch summary cache txt cord-262780-ilu5oskk Sattui, Sebastian E. Swinging the pendulum: lessons learned from public discourse concerning hydroxychloroquine and COVID-19 2020-08-11 .txt text/plain 4653 251 48 The use of chloroquine (CQ) and hydroxychloroquine (HCQ) for COVID-19 exemplifies the risks of both overinterpreting and amplifying preliminary data by those outside of the scientific community and was followed by swift corrective measures by researchers. By early March, interest in HCQ abruptly transitioned from mechanistic plausibility that would support its study in a clinical trial setting to rapid off-label use in patients with COVID-19, primarily fueled by promotion on social media, lay press, and celebrity influence [8] . By late March, two new studies became publicly available: a second study from the group of IHU-Méditerranée Infection using HCQ and AZM in 80 patients with mild COVID-19 infection released on their webpage, and a preprint of the first randomized controlled trial of 62 patients from Wuhan reporting a difference in clinical time to recovery and radiologic findings with HCQ treatment [22, 23] . ./cache/cord-262780-ilu5oskk.txt ./txt/cord-262780-ilu5oskk.txt