id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-264462-4vfk99f5	Piscoya, A.	Efficacy and harms of remdesivir for the treatment of COVID-19: a systematic review and meta-analysis	2020-05-27		.txt	text/plain	3555	240	57	Methods: Systematic review in five engines, pre-print webpages and RCT registries until May 22, 2020 for randomized controlled trials (RCTs) and observational studies evaluating remdesivir on confirmed, COVID-19 adults with pneumonia and/or respiratory insufficiency. We performed a systematic review of RCTs and observational studies (cohort studies, case series) evaluating the effects of remdesivir in adult hospitalized COVID-19 confirmed patients. In adult, hospitalized, RT-PCR confirmed COVID-19 patients with respiratory insufficiency or pneumonia, there was scarce data on efficacy and safety associated with the use of 10-day remdesivir regimens. 6 There is paucity of adequately powered and fully reported RCTs evaluating efficacy and harms of remdesivir use in adult, hospitalized, severely-ill COVID-19 patients. Evaluation of the Efficacy and Safety of Intravenous Remdesivir in Adult Patients with Severe Pneumonia caused by COVID-19 virus Infection: study protocol for a Phase 3 Randomized, Double-blind, Placebo-controlled, Multicentre trial	./cache/cord-264462-4vfk99f5.txt	./txt/cord-264462-4vfk99f5.txt