id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-264673-67zopf7s	Shi, Hongbo	The inhibition of IL-2/IL-2R gives rise to CD8(+) T cell and lymphocyte decrease through JAK1-STAT5 in critical patients with COVID-19 pneumonia	2020-06-08		.txt	text/plain	3359	209	55	The count and percentage of lymphocytes were significantly decreased in critical patients compared to common and severe patients with COVID-19 pneumonia. The absolute lymphocyte count in patients with COVID-19 pneumonia was remarkably decreased compared with normal controls (Fig. 1a) . In addition, the percentage of lymphocyte in white blood cells (WBC) decreased in turn in common, severe, and critical patients, and the differences among them were statistically significant (Fig. 1d) . In addition, the expression of IL-2Rβ and IL-2Rγc in common, severe, and critical patients was significantly lower than that in normal Table 1 Clinical categorization of the patients with COVID-19 pneumonia by National Health Commission of China. The most significant finding of this study was the low level of IL-2 in plasma and low expression of IL-2R in PBMC of critical patients, which may result in the remarkable decrease of CD8 + T cell and lymphocytes in critical patients with COVID-19 pneumonia.	./cache/cord-264673-67zopf7s.txt	./txt/cord-264673-67zopf7s.txt