id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-266394-ehh61x5c	Katsoulis, M.	Obesity during the COVID-19 pandemic: cause of high risk or an effect of lockdown? A population-based electronic health record analysis in 1 958 184 individuals.	2020-06-23		.txt	text/plain	3883	184	51	Methods: In population-based electronic health records for 1 958 638 individuals in England, we estimated 1-year mortality risk('direct' and 'indirect' effects) for obese individuals, incorporating: (i)pre-COVID-19 risk by age, sex and comorbidities, (ii)population infection rate, and (iii)relative impact on mortality(relative risk, RR: 1.2, 1.5, 2.0 and 3.0). Using causal inference models, we estimated impact of change in body-mass index(BMI) and physical activity during 3-month lockdown on 1-year incidence for high-risk conditions(cardiovascular diseases, CVD; diabetes; chronic obstructive pulmonary disease, COPD and chronic kidney disease, CKD), accounting for confounders. Using population-based electronic health records (EHR) in England, we estimated: (i) background mortality in severe obesity by underlying risk factors; (ii) direct and indirect excess deaths in individuals with severe obesity; and (iii) impact of BMI gain and physical activity on the incidence of the most common high-risk diseases for COVID-19, and mortality.	./cache/cord-266394-ehh61x5c.txt	./txt/cord-266394-ehh61x5c.txt