id author title date pages extension mime words sentences flesch summary cache txt cord-268062-f03acrrd Weaver, Michael COVID-19 and Jaundice 2020-10-08 .txt text/plain 769 45 46 This is sclerosing cholangitis in critically ill patients (SC-CIP) and biliary cast syndrome likely as sequelae of SARS-CoV-2 (COVID-19) infection. 2 Secondary sclerosing cholangitis is characterized by multifocal biliary stricturing and can be due to a variety of causes including infection and ischemic cholangitis among others. 3 Here we postulate that our patient developed SC-CIP and biliary cast syndrome as sequelae of COVID-19 infection. The resultant hypotension and shock from the initial COVID-19 infection likely precipitated biliary ischemia and subsequent sclerosing cholangitis with biliary cast formation. Furthermore, it is plausible that the patient may have developed local microthrombi and microangiopathy, akin to the pulmonary vascular thrombosis and microangiopathy observed in COVID-19 autopsy specimens, 2 resulting in biliary ischemia, especially in a prothrombotic patient who developed bilateral DVTs who could not be anticoagulated. ./cache/cord-268062-f03acrrd.txt ./txt/cord-268062-f03acrrd.txt