id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-268453-87b298uk	Ibáñez, Sebastián	Hydroxychloroquine and chloroquine in COVID-19: should they be used as standard therapy?	2020-06-03		.txt	text/plain	3500	150	48	In the absence of a vaccine and specifically designed antivirals, the medical community has proposed the use of various previously available medications in order to reduce the number of patients requiring prolonged hospitalizations, oxygen therapy, and mechanical ventilation and to decrease mortality from coronavirus disease 2019 (COVID-19). HCQ was, in vitro, at least as effective as chloroquine in inhibiting SARS-CoV-2 infection, although it should be noted that studies on its mechanisms of action are not as extensive as with CQ [30] . The evidence for the use of hydroxychloroquine or chloroquine in COVID-19 is not good so far, not only because of the negative results of most of the studies but also because of their design, when publishing results of a very low number of patients, when reporting favorable results but without having a control group that allows comparison, when choosing results for which it will be very difficult to find significant differences, such as mortality, or for which their clinical relevance is uncertain.	./cache/cord-268453-87b298uk.txt	./txt/cord-268453-87b298uk.txt