id author title date pages extension mime words sentences flesch summary cache txt cord-269417-dtu7711x Hirashima, Tomonori Factors significantly associated with COVID-19 severity in symptomatic patients: A retrospective single-center study 2020-10-10 .txt text/plain 4080 225 51 CONCLUSIONS: The illness severity of Japanese COVID-Pts was associated with older age, hypertension and/or diabetes, low serum albumin, high neutrophil-to-lymphocyte ratio, and C-reactive protein. Therefore, we undertook this study, among mainly Japanese patients, to examine factors significantly associated with COVID-19 severity in symptomatic patients. As specified in the National Institutes of Health (NIH) COVID-19 Treatment Guidelines [12] , in this study, the illness severity of patients with COVID-19 at the time of hospitalization was stratified into the following four categories: asymptomatic or presymptomatic infection, mild/moderate, severe, and critical illness. To the best of our knowledge, this is the first study to describe in detail, the factors associated with both disease severity and the treatment approach, including tocilizumab and IHDMPPT among Japanese COVID-19-pts. A recent study [17] reported the clinical characteristics of COVID-19 in 104 people with SARS-CoV-2 infection on a cruise ship in Japan. ./cache/cord-269417-dtu7711x.txt ./txt/cord-269417-dtu7711x.txt