id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-269563-2979u47a	Caetano Silva-Filho, José	The influence of ABO blood groups on COVID-19 susceptibility and severity: a molecular hypothesis based on carbohydrate-carbohydrate interactions	2020-08-02		.txt	text/plain	4614	218	40	Based on this survey, we hypothesize that the correlation between the ABO blood system and susceptibility to SARS-CoV-2 infection can be presumably explained by the modulation of sialic acid-containing receptors distribution on host cell surface induced by ABO antigens through carbohydrate-carbohydrate interactions, which could maximize or minimize the virus Spike protein binding to the host cell. to cell receptors, as well as (ii) the biochemical aspects of ABO blood group system and its association to infection and some circulatory conditions, we hypothesize that the influence of blood type on COVID-19 severity relies on the differential clustering of glycoproteins receptors to SARS-CoV-2 on host cell surface, induced by ABH antigens through carbohydrate-carbohydrate interactions with the glycan portions of these receptors, which could modulate virus binding to the target cell.	./cache/cord-269563-2979u47a.txt	./txt/cord-269563-2979u47a.txt