id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-270528-3rsv3jlh	Yazdanpanah, Fereshteh	The immune system and COVID-19: Friend or foe?	2020-06-02		.txt	text/plain	3134	192	48	The pathogenesis of this virus is not yet clearly understood, but there is evidence of a hyper-inflammatory immune response in critically ill patients, which leads to acute respiratory distress syndrome (ARDS) and multi-organ failure. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes the coronavirus disease 2019 (COVID19) , and has affected people's lives globally, since first observed in Wuhan, China in the last days of 2019 (1, 2) . On the other hand, the hyper-inflammatory and cytokine release syndrome (CRS) typical of COVID-19 causes tissue damage to the lung epithelium and ARDS (32); therefore, immunosuppressive drugs may be useful as there is some evidence that an anti-IL-6 approach is effective in critically ill patients in the ICU (33) . Also, due to the overexpression of ACE2 in islet cells of the pancreas, SARS-CoV-2 may be a diabetogenic virus that causes severe instability in the blood glucose levels of diabetes patients, which worsens the inflammatory imbalance (37) .	./cache/cord-270528-3rsv3jlh.txt	./txt/cord-270528-3rsv3jlh.txt