id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-272452-tfj8j9ww	Berger, Jeffrey S.	Prevalence and Outcomes of D-Dimer Elevation in Hospitalized Patients With COVID-19	2020-08-25		.txt	text/plain	3368	190	41	CONCLUSIONS: Abnormal D-dimer was frequently observed at admission with COVID-19 and was associated with higher incidence of critical illness, thrombotic events, acute kidney injury, and death. Given that widespread microthrombi have been observed in COVID-19 in multiple organ systems, 20, 21 we hypothesized that elevated D-dimer levels would be associated with increased risk of clinically diagnosed thrombotic events, acute kidney injury, critical illness, and death among patients hospitalized with COVID-19. We analyzed data from a large health system in New York City to examine the prevalence of D-dimer elevation at presentation and over time, and the association of the biomarker with incident thrombosis as well as acute kidney injury, critical illness, all-cause mortality, and likelihood of being discharged. D-dimer levels were independently associated with a higher risk of critical illness, thrombosis, acute kidney injury, and all-cause mortality among patients with COVID-19, independent of previously identified risk factors.	./cache/cord-272452-tfj8j9ww.txt	./txt/cord-272452-tfj8j9ww.txt