id author title date pages extension mime words sentences flesch summary cache txt cord-273618-klj6asdz Jain, Ankur Potential ‘significance’ of monoclonal gammopathy of ‘undetermined significance’ during COVID-19 pandemic 2020-07-24 .txt text/plain 1723 116 49 9, 11 In the NY studies, ICU admission rates of COVID-19 positive MM patients were higher as compared to the general COVID-19 population (24-30% vs 14.2%). 38 @ Patients with severe renal impairment (estimated glomerular filtration rate <30 ml/minutes/1.73m 2 , on hemodialysis, or peritoneal dialysis) were excluded from the recent Remdesivir trials 33 Review of the nation-wide hospital data of COVID-19 cases to identify patients with concurrent MGUS, and comparison of disease severity, outcomes, and differences in the immunological indices between MGUS, and non-MGUS groups. In-vitro studies based on lymphocyte-stimulation by SARS-CoV-2 antigens to assess the immune-responsiveness of people with MGUS to COVID-19 vaccines. 39 ** Since people with MGUS may have an impaired anti-viral antibody response, 4 a lower SARS-CoV-2-specific IgG in the MGUS population as compared to the HC in the serology-based epidemiological studies would suggest an increased susceptibility of people with MGUS to COVID-19 ./cache/cord-273618-klj6asdz.txt ./txt/cord-273618-klj6asdz.txt