id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-273644-m6cub4sx	Zhang, Yimin	A Promising Anti-Cytokine-Storm Targeted Therapy for COVID-19: The Artificial-Liver Blood-Purification System	2020-03-20		.txt	text/plain	1653	76	41	A previous study revealed high levels of pro-inflammatory cytokines/chemokines (e.g., IL-2, IL-7, IL-10, granulocyte-colony stimulating factor (GCSF), IP-10, MCP-1, macrophage inflammatory protein 1 a (MIP1A), and TNF-a) in severely and critically ill patients with COVID-19 infection; furthermore, the presence of cytokine storm was correlated with disease severity [3] . The experience gained in the treatment of critically ill patients with H7N9 influenza infection and cytokine storm revealed the high efficacy of plasma-exchange modules in artificial-liver blood-purification systems, based on the extent of cytokine clearance [19] . The artificial-liver blood-purification system was applied in Zhejiang province, China, and showed good prognosis in the treatment of severely or critically ill COVID-19 patients with cytokine storm [22] . This work recommends artificial-liver blood purification for the treatment of patients with COVID-19 infection who exhibit cytokine storm and rapid disease progression, as confirmed by lung imaging.	./cache/cord-273644-m6cub4sx.txt	./txt/cord-273644-m6cub4sx.txt