id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-274666-0d8oz51l	Han, Yi	Lactate dehydrogenase, an independent risk factor of severe COVID-19 patients: a retrospective and observational study	2020-06-24		.txt	text/plain	3807	197	54	Conclusions: This study showed that LDH could be identified as a powerful predictive factor for early recognition of lung injury and severe COVID-19 cases. To assess the risk factors of the demographics, characteristics, and laboratory indicators on the severity of COVID-19 patients, logistic regression analysis was performed on the parameters of significant difference using t test. Apart from the risk factors above, patient age, white blood cell count, neutrophil count, serum AST, ALT, LDH, Urea, CRP, and D-dimer level were all associated with the severity of COVID-19 patients. As a result, serum lymphocytes (OR:0.2, 95% CI:0.04-0.96, P < 0.05), CRP (OR:1.026, 95% CI:1.006-1.046, P < 0.05), and LDH (OR:1.009, 95% CI:1.002-1.016, P < 0.05) were found to be independent risk factors for the severity of COVID-19 patients ( Table 3) . And importantly, lymphocytes, especially CD3 + , CD4 + , and CD8 + T cells in the peripheral blood of COVID-19 patients, which was relevant with serum LDH, were also dynamically correlated with the severity of the disease.	./cache/cord-274666-0d8oz51l.txt	./txt/cord-274666-0d8oz51l.txt