id author title date pages extension mime words sentences flesch summary cache txt cord-275136-7atkrkhd Dolin, Raphael Remdesivir — An Important First Step 2020-05-27 .txt text/plain 996 49 46 have provided in the Journal the first report of an effective treatment for Covid-19, resulting from a rigorously designed and conducted clinical trial. On May 1, 2020, the Food and Drug Administration issued an Emergency Use Authorization for remdesivir to treat adults and children with severe Covid-19. However, the effect on time to recovery was observed largely in patients who entered the study in the severe disease stratum (12 days in remdesivir recipients, as compared with 18 days in placebo recipients). The findings in the trial suggest that the timing of initiation of treatment with an antiviral such as remdesivir, as well as the underlying clinical status of the patient, may have important effects on the outcomes of therapy. In an accompanying article by Goldman et al., investigators studied the effects of remdesivir on Covid-19 outcomes when treatment was given for 5 days as compared with 10 days. shows that remdesivir provides moderate clinical benefit in the treatment of patients with Covid-19. ./cache/cord-275136-7atkrkhd.txt ./txt/cord-275136-7atkrkhd.txt