id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-275506-3t5gf66c	Agbuduwe, Charles	Hematolological Manifestations of COVID‐19: From Cytopenia to Coagulopathy	2020-07-14		.txt	text/plain	4280	265	39	[45] A retrospective study of COVID-19 patients admitted to ICU identified DVT in 25% with advanced age, lower lymphocyte counts and elevated D-dimers being significant risk factors. [63] Currently, the evidence base for the clinical management of COVID-19 is mostly limited to case series and other relatively small observational studies of hospitalised patients. Similar to findings in SARS patients, [64] lymphopenia is the most commonly reported hematological abnormality in COVID-19 and recent data shows that it can be predictive of disease severity. The use of convalescent plasma may, in addition, provide neutralising antibodies against SARS-CoV-2 and a small-scale clinical trial has reported modest but encouraging results in severely-ill but not in critical COVID-19 patients. In view of the increased thrombotic risk associated with COVID-19, prophylactic anticoagulation with low Accepted Article molecular weight heparin is recommended for all hospitalised patients with the disease and clinical trials are needed to investigate the role of more intensive anticoagulation and other experimental therapies.	./cache/cord-275506-3t5gf66c.txt	./txt/cord-275506-3t5gf66c.txt