id author title date pages extension mime words sentences flesch summary cache txt cord-277774-kec1o4ys Wang, Shangqian The need for urogenital tract monitoring in COVID-19 2020-04-20 .txt text/plain 1528 84 48 Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2, which invades a cell through binding to the ACE2 receptor and TMPRSS2 priming. Most patients with severe COVID-19 present with pneumonia-related symptoms, but some patients with severe disease could develop serious urinary complications including acute kidney injury (AKI), which requires continuous renal replacement therapy (CRRT) 1 . Furthermore, male reproductive systems are vulnerable to infection; dramatic changes in sex hormones in patients with COVID-19 have been observed, suggesting gonadal function impairment 2 . Similar findings were also observed in autopsy kidney samples from patients with MERS-CoV infection 4 , which showed degeneration of the renal tubules, including ectasia changes and necrosis, sloughing, and loss of brush surface in the proximal tubular epithelial cells. Human kidney is a target for novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection ./cache/cord-277774-kec1o4ys.txt ./txt/cord-277774-kec1o4ys.txt