id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-278068-3kg71nf4	Chivese, T.	A meta-review of systematic reviews and an updated meta-analysis on the efficacy of chloroquine and hydroxychloroquine in treating COVID19 infection	2020-07-30		.txt	text/plain	9798	582	53	Objective To synthesize the findings presented in systematic reviews and meta-analyses as well as to update the evidence using a meta-analysis in evaluating the efficacy and safety of CQ and HCQ with or without Azithromycin for the treatment of COVID19 infection. A comprehensive search included several electronic databases in identifying all systematic reviews and meta-analyses as well as experimental studies which investigated the efficacy and safety of CQ, HCQ with or without antibiotics as COVID19 treatment. To synthesize the findings presented in systematic reviews and meta-analyses as well as to update the evidence using a meta-analysis in evaluating the efficacy and safety of CQ and HCQ with or without Azithromycin for the treatment of COVID19 infection. In this respect, we conducted this umbrella review with two broad aims; (1) to assess the efficacy and safety of each of HCQ and CQ, with or without Azithromycin in the treatment of COVID19 by assessing the evidence from existing systematic reviews and metaanalyses, and (2) to carry out an updated meta-analysis of the existing experimental studies to assess the efficacy of these drugs.	./cache/cord-278068-3kg71nf4.txt	./txt/cord-278068-3kg71nf4.txt