id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-279115-eyk8sxk7	Cecconi, Maurizio	Ten things we learned about COVID-19	2020-06-05		.txt	text/plain	1621	106	51	The infection starts with the competition between the SARS-CoV-2 virions arrived in the respiratory mucosa that express high levels of ACE2 receptors and the barrier made by mucus secreted by goblet cells and moved by hair-like cilia and innate immunity reactions. Evidence from SARS-CoV-1 suggests that these viruses may block interferon-mediated antiviral immunity (Fig. 1 ). Inflammation plays a key role in the development of COVID-19 from a SARS-CoV-2 infection. Unsurprisingly for a disease characterised by an inflammatory state in response to a viral infection, venous and arterial thromboembolic complications are common in hospitalised patients [6] . Given the timing and characteristics of the antibody response (see above), appropriately validated assays are instrumental for epidemiological studies, evaluation of plasma donations (see below), assessment of memory and response to vaccine, and as a companion diagnostic in RT-PCR-negative patients. Baseline characteristics and outcomes of 1591 patients infected with SARS-CoV-2 admitted to ICUs of the Lombardy Region	./cache/cord-279115-eyk8sxk7.txt	./txt/cord-279115-eyk8sxk7.txt