id author title date pages extension mime words sentences flesch summary cache txt cord-279913-lgdmlies Katz, D. H. Proteomic Profiling in Biracial Cohorts Implicates DC-SIGN as a Mediator of Genetic Risk in COVID-19 2020-06-11 .txt text/plain 4032 229 52 To understand how these loci might confer risk and whether this differs by race, we utilized proteomic profiling and genetic information from three cohorts including black and white participants to identify proteins influenced by these loci. We tested for associations between genetic variants at the ABO and 3p21.31 loci and protein levels in the three cohorts to identify possible mediators of disease. Table 1 shows the 56 proteins that associate with variants within 1MB of the transcription start site (TSS) of the ABO gene in either JHS or FHS/MDCS or both at a p-value < 5×10 -8 . . https://doi.org/10.1101/2020.06.09.20125690 doi: medRxiv preprint Proteins associated with any variant within 1MB of transcription start site of ABO gene in either Jackson Heart Study (JHS) or Framingham Heart Study (FHS)/Malmö Diet and Cancer Study (MDCS). Proteins associated with any variant within chr3:45800446-46135604 of hg38 in either Jackson Heart Study (JHS) or Framingham Heart Study (FHS)/Malmö Diet and Cancer Study (MDCS) meta-analysis. ./cache/cord-279913-lgdmlies.txt ./txt/cord-279913-lgdmlies.txt