id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-280231-jo3grxd5	Hardenberg, Jan‐Hendrik	Covid‐19, ACE2 and the kidney	2020-08-02		.txt	text/plain	3901	285	55	Corona-virus disease 2019 (Covid-19) is a global pandemic of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). 15 A cryo-electron microscopy structures of full-length human ACE2 in the presence of the neutral amino acid transporter collectrin (also known as B 0 AT1), with or without the receptor SARS-CoV2 binding domain (RBD), of the surface spike glycoprotein (S protein) of SARS-CoV-2, both at an overall resolution of 2.9 angstroms, with a local resolution of 3.5 F I G U R E 1 Evolution of the "anginotensin converting enzyme" (ACE) family. 25 That Covid-19 patients develop acute kidney injury (AKI) would not be a surprise. Progressive respiratory failure, not renal failure, is the primary T A B L E 1 A brief overview of Covid-19 patients, acute kidney injury (AKI) and renal-replacement therapies (RRT) Stepwise multivariate binary logistic regression analyses showed that severity of pneumonia was the risk factor most commonly associated with lower odds of proteinuric or haematuric remission and recovery from AKI.	./cache/cord-280231-jo3grxd5.txt	./txt/cord-280231-jo3grxd5.txt